Osteoprotegerin/TNFRSF11B Protein 185-OS-025 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemOsteoprotegerin/TNFRSF11B Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $445.00Supplier Page View Company Product Page
Catalog Number185-OS-025
SpeciesHuman
Size25 ug
Molecule NameOsteoprotegerin/TNFRSF11B
FormatLyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein
Purity>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemNS0-derived Recombinant Human Osteoprotegerin/TNFRSF11B Protein
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Full Gene NameTNF receptor superfamily member 11b
NCBI Gene AliasesOCIF, OPG, PDB5, TR1

Specifications/Features

Available conjugates: Sizes Available: 25 ug

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Collagen networks within 3D PEG hydrogels support valvular interstitial cell matrix mineralizationActa BiomaterialiaJanuary 1, 2021Megan E. Schroeder, Andrea Gonzalez Gonzalez Rodriguez, Kelly F. Speckl, Cierra J. Walker, Firaol S. Midekssa, Joseph C. Grim, Robert M. Weiss, Kristi S. AnsethSML0223), rosmarinic acid (Sigma-Aldrich R4033), and recombinant human osteoprotegerin (Novus Biologicals, 185-OS-025). These therapeutics were all soluble in either H2O or PBS. 2.6 mRNA Isolation and RT-qPCR Assessment

(2) Effects of osteoprotegerin/TNFRSF11B in two models of abdominal aortic aneurysmsMolecular medicine reportsJuly 1, 2018Vorkapic E, Kunath A, Wågsäter D.

(3) Mutations in osteoprotegerin account for the CCAL1 locus in calcium pyrophosphate deposition diseaseOsteoarthritis and cartilageJune 1, 2018Williams CJ, Qazi U, Bernstein M, Charniak A, Gohr C, Mitton-Fitzgerald E, Ortiz A, Cardinal L, Kaell AT, Rosenthal AK.

(4) Modeling human pancreatic beta cell dedifferentiationMolecular metabolismApril 1, 2018Diedisheim M, Oshima M, Albagli O, Huldt CW, Ahlstedt I, Clausen M, Menon S, Aivazidis A, Andreasson AC, Haynes WG, et al.

(5) Microenvironment-Induced Non-sporadic Expression of the AXL and cKIT Receptors Are Related to Epithelial Plasticity and Drug ResistanceFrontiers in cell and developmental biologyJanuary 1, 2018Jokela TA, Engelsen AST, Rybicka A, Pelissier Vatter FA, Garbe JC, Miyano M, Tiron C, Ferariu D, Akslen LA, Stampfer MR, et al.,Novus Biologicals,NBC1-21056,"1 μg/ml, (Insua-Rodriguez and Oskarsson, 2016)" Osteoprotegerin (OPG),R&D systems,185-OS-025,"1 μg/ml, (Weichhaus et al., 2015)" Stem cell factor (SCF),R&D systems,255-SC-010,"1 μg/ml, (Mimeault

(6) RANKL-mediated harmonious dialogue between fetus and mother guarantees smooth gestation by inducing decidual M2 macrophage polarizationCell death & diseaseOctober 12, 2017Meng YH, Zhou WJ, Jin LP, Liu LB, Chang KK, Mei J, Li H, Wang J, Li DJ, Li MQ.addition, 5 μg/ml anti-human RANKL neutralizing antibody (AB626, R&D Systems), 100 ng/ml rhOPG protein (185-OS-025, R&D Systems), 10 μM LY294002 (Cells Signal Technology, Danvers, MA, USA) or 21 nM STAT6 signal inhibitor

(7) Osteoprotegerin promotes the proliferation of chondrocytes and affects the expression of ADAMTS-5 and TIMP-4 through MEK/ERK signalingMolecular medicine reportsDecember 1, 2013Feng ZY, He ZN, Zhang B, Chen Z.

(8) Osteoprotegerin (OPG) activates integrin, focal adhesion kinase (FAK), and Akt signaling in ovarian cancer cells to attenuate TRAIL-induced apoptosisJournal of ovarian researchNovember 23, 2013Lane D, Matte I, Laplante C, Garde-Granger P, Rancourt C, Piché A.

(9) Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitorsNatureJuly 26, 2012Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, Peng J, Lin E, Wang Y, Sosman J, et al.

(10) Interleukin-32 promotes osteoclast differentiation but not osteoclast activationPloS oneJanuary 1, 2009Mabilleau G, Sabokbar A.

(11) Osteoprotegerin decreases human osteoclast apoptosis by inhibiting the TRAIL pathwayJournal of cellular physiologyAugust 1, 2008Chamoux E, Houde N, L'Eriger K, Roux S.

(12) Activation of the p53 pathway down-regulates the osteoprotegerin expression and release by vascular endothelial cellsBloodFebruary 1, 2008Secchiero P, Corallini F, Rimondi E, Chiaruttini C, di Iasio MG, Rustighi A, Del Sal G, Zauli G.

(13) Selective targeting of death receptor 5 circumvents resistance of MG-63 osteosarcoma cells to TRAIL-induced apoptosisMolecular cancer therapeuticsDecember 1, 2007Locklin RM, Federici E, Espina B, Hulley PA, Russell RG, Edwards CM.

(14) Impairment of the antifibrotic effect of hepatocyte growth factor in lung fibroblasts from African Americans: possible role in systemic sclerosisArthritis and rheumatismJuly 1, 2007Bogatkevich GS, Ludwicka-Bradley A, Highland KB, Hant F, Nietert PJ, Singleton CB, Feghali-Bostwick CA, Silver RM.

(15) Attenuation of bone mass and increase of osteoclast formation in decoy receptor 3 transgenic miceThe Journal of biological chemistryJanuary 26, 2007Tang CH, Hsu TL, Lin WW, Lai MZ, Yang RS, Hsieh SL, Fu WM.

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Osteoprotegerin/TNFRSF11B Protein from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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Osteoprotegerin/TNFRSF11B Protein from R&D Systems, a Bio-Techne Brand

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