Recombinant Mouse TGF-beta RII/(mouse) Fc Chimera, CF 1600-R2-050 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Mouse TGF-beta RII/(mouse) Fc Chimera, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $504.00Supplier Page View Company Product Page
Catalog Number1600-R2-050
SpeciesMouse
FormatLyophilized from a 0.2 µm filtered solution in PBS
Molecule NameTGF-beta RII
Size50 ug
NCBI Full Gene Nametransforming growth factor, beta receptor II
NCBI Gene AliasesRIIDN, TbetaR-II, 1110020H15Rik, TBR-II, TbetaRII, DNIIR
Purity>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 66 kDa, reducing conditions
Theoretical: 45.2 kDa (monomer)
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemNS0-derived Recombinant Mouse TGF-beta RII/(mouse) Fc Chimera, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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(3) Soluble endoglin specifically binds bone morphogenetic proteins 9 and 10 via its orphan domain, inhibits blood vessel formation, and suppresses tumor growthThe Journal of biological chemistryAugust 26, 2011Castonguay R, Werner ED, Matthews RG, Presman E, Mulivor AW, Solban N, Sako D, Pearsall RS, Underwood KW, Seehra J, et al.

(4) Combined intratumoral regulatory T-cell depletion and transforming growth factor-β neutralization induces regression of established AE17 murine mesothelioma tumorsJournal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine ResearchApril 1, 2009Kissick HT, Ireland DJ, Beilharz MW.

(5) TLR4 enhances TGF-beta signaling and hepatic fibrosisNature medicineNovember 1, 2007Seki E, De Minicis S, Osterreicher CH, Kluwe J, Osawa Y, Brenner DA, Schwabe RF.

Recombinant Mouse TGF-beta RII/(mouse) Fc Chimera, CF from R&D Systems, a Bio-Techne Brand