Recombinant Mouse B7-2/CD86 Fc Chimera Protein, CF 741-B2-100 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Mouse B7-2/CD86 Fc Chimera Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $465.00Supplier Page View Company Product Page
Catalog Number741-B2-100
SpeciesMouse
Size100 ug
Molecule NameB7-2/CD86
FormatLyophilized from a 0.2 µm filtered solution in PBS
Source/Expression SystemSf 21 (baculovirus)-derived Recombinant Mouse B7-2/CD86 Fc Chimera Protein, CF
NCBI Full Gene NameCD86 antigen
NCBI Gene AliasesB70, B7.2, ETC-1, CLS1, Ly-58, B7-2, B7, MB7-2, Ly58, MB7, TS/A-2, Cd28l2
Purity>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 60-65 kDa, reducing conditions
Theoretical: 51.8 kDa (monomer)
ApplicationsBioactivity
Conjugate/TagUnconjugated
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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(1) Aire suppresses CTLA-4 expression from the thymic stroma to control autoimmunityCell reportsFebruary 15, 2022Morimoto J, Matsumoto M, Miyazawa R, Yoshida H, Tsuneyama K, Matsumoto M.

(2) Inhibition of the kinase Csk in thymocytes reveals a requirement for actin remodeling in the initiation of full TCR signalingNature immunologyFebruary 1, 2014Tan YX, Manz BN, Freedman TS, Zhang C, Shokat KM, Weiss A.(1031-50), rabbit anti-hamster IgG (H+L) (6215-05) are from Southern Biotech; B7.2 Ig (R&D Systems 741-B2-100). Flow Cytometry and data analyses Stained cells were analyzed on a BD Fortessa (BD Biosciences).

(3) Cooperative B7-1/2 (CD80/CD86) and B7-DC costimulation of CD4+ T cells independent of the PD-1 receptorThe Journal of experimental medicineJuly 7, 2003Shin T, Kennedy G, Gorski K, Tsuchiya H, Koseki H, Azuma M, Yagita H, Chen L, Powell J, Pardoll D, et al.

Recombinant Mouse B7-2/CD86 Fc Chimera Protein, CF from R&D Systems, a Bio-Techne Brand