Recombinant Mouse CXCL10/IP-10/CRG-2 Protein 466-CR-010 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Mouse CXCL10/IP-10/CRG-2 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $338.00Supplier Page View Company Product Page
Catalog Number466-CR-010
SpeciesMouse
Molecule NameCXCL10/IP-10/CRG-2
Size10 ug (also 50 ug)
NCBI Full Gene Namechemokine (C-X-C motif) ligand 10
NCBI Gene AliasesgIP-10, INP10, IP10, IP-10, mob-1, Ifi10, CRG-2, C7, Scyb10
FormatLyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein
Purity>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular Weight8.8 kDa
Conjugate/TagUnconjugated
Source/Expression SystemE. coli-derived Recombinant Mouse CXCL10/IP-10/CRG-2 Protein
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) CXCL10 Secreted by Pericytes Mediates TNFα-Induced Vascular Leakage in Tumors and Enhances Extravasation of Nanoparticle-Based ChemotherapeuticsCancer researchMay 2, 2025Seynhaeve ALB, Liu H, Priester MI, Valentijn M, van Holten-Neelen C, Brouwer RWW, van Brakel M, Dik WA, van IJcken WFJ, Debets R, et al.

(2) PD-1 combination therapy with IL-2 modifies CD8(+) T cell exhaustion programNatureOctober 1, 2022Hashimoto M, Araki K, Cardenas MA, Li P, Jadhav RR, Kissick HT, Hudson WH, McGuire DJ, Obeng RC, Wieland A, et al.

(3) Dissection of α₄β₇ integrin regulation by Rap1 using novel conformation-specific monoclonal anti-β₇ antibodiesScientific reportsAugust 6, 2020Sato T, Ishihara S, Marui R, Takagi J, Katagiri K.

(4) Prion protein N1 cleavage peptides stimulate microglial interaction with surrounding cellsScientific reportsApril 20, 2020Carroll JA, Groveman BR, Williams K, Moore R, Race B, Haigh CL.

(5) Tumor suppressor TET2 promotes cancer immunity and immunotherapy efficacyThe Journal of clinical investigationJuly 16, 2019Xu YP, Lv L, Liu Y, Smith MD, Li WC, Tan XM, Cheng M, Li Z, Bovino M, Aubé J, et al.B16-OVA control or Tet2-KO cells, with or without 100 ng/mL recombinant murine CXCL10 (R&D Systems, catalog 466-CR-010). For blockade of CXCR3, T cells were preincubated in 10 μg/mL anti-CXCR3 (BioLegend, 126517) for 30

(6) Chemokine-Binding Proteins Encoded by Parapoxvirus of Red Deer of New Zealand Display Evidence of Gene Duplication and Divergence of Ligand SpecificityFrontiers in microbiologyJanuary 1, 2019Sharif S, Ueda N, Nakatani Y, Wise LM, Clifton S, Lateef Z, Mercer AA, Fleming SB.

(7) A novel function of CXCL10 in mediating monocyte production of proinflammatory cytokinesJournal of leukocyte biologyNovember 1, 2017Zhao Q, Kim T, Pang J, Sun W, Yang X, Wang J, Song Y, Zhang H, Sun H, Rangan V, et al.

(8) NK cell heparanase controls tumor invasion and immune surveillanceThe Journal of clinical investigationJune 30, 2017Putz EM, Mayfosh AJ, Kos K, Barkauskas DS, Nakamura K, Town L, Goodall KJ, Yee DY, Poon IK, Baschuk N, et al.

(9) Protected graft copolymer-formulated fibroblast growth factors mitigate the lethality of partial body irradiation injuryPloS oneJanuary 1, 2017Castillo GM, Nishimoto-Ashfield A, Jones CC, Kabirov KK, Zakharov A, Lyubimov AV.

(10) Induced Regulatory T Cells Superimpose Their Suppressive Capacity with Effector T Cells in Lymph Nodes via Antigen-Specific S1p1-Dependent Egress BlockageFrontiers in immunologyJanuary 1, 2017Geng S, Zhong Y, Zhou X, Zhao G, Xie X, Pei Y, Liu H, Zhang H, Shi Y, Wang B.

(11) Monocyte- and Neutrophil-Derived CXCL10 Impairs Efficient Control of Blood-Stage Malaria Infection and Promotes Severe DiseaseJournal of immunology (Baltimore, Md. : 1950)February 1, 2016Ioannidis LJ, Nie CQ, Ly A, Ryg-Cornejo V, Chiu CY, Hansen DS.

(12) Interferon-γ Promotes Inflammation and Development of T-Cell Lymphoma in HTLV-1 bZIP Factor Transgenic MicePLoS pathogensAugust 1, 2015Mitagami Y, Yasunaga J, Kinosada H, Ohshima K, Matsuoka M.

(13) CXCL10 triggers early microglial activation in the cuprizone modelJournal of immunology (Baltimore, Md. : 1950)April 1, 2015Clarner T, Janssen K, Nellessen L, Stangel M, Skripuletz T, Krauspe B, Hess FM, Denecke B, Beutner C, Linnartz-Gerlach B, et al.

(14) TRIF-dependent innate immune activation is critical for survival to neonatal gram-negative sepsisJournal of immunology (Baltimore, Md. : 1950)February 1, 2015Cuenca AG, Joiner DN, Gentile LF, Cuenca AL, Wynn JL, Kelly-Scumpia KM, Scumpia PO, Behrns KE, Efron PA, Nacionales D, et al.

(15) CXCR3 promotes plaque formation and behavioral deficits in an Alzheimer's disease modelThe Journal of clinical investigationJanuary 1, 2015Krauthausen M, Kummer MP, Zimmermann J, Reyes-Irisarri E, Terwel D, Bulic B, Heneka MT, Müller M.

(16) Macrophage-inducing FasL on chondrocytes forms immune privilege in cartilage tissue engineering, enhancing in vivo regenerationStem CellsMay 1, 2014Fujihara Y, Takato T, Hoshi K.

(17) Early differentiated CD138(high) MHCII+ IgG+ plasma cells express CXCR3 and localize into inflamed kidneys of lupus micePloS oneJanuary 1, 2013Lacotte S, Decossas M, Le Coz C, Brun S, Muller S, Dumortier H.

(18) TLR2-mediated production of IL-27 and chemokines by respiratory epithelial cells promotes bleomycin-induced pulmonary fibrosis in miceJournal of immunology (Baltimore, Md. : 1950)October 15, 2011Kim HS, Go H, Akira S, Chung DH.

(19) Chemokine receptor CXCR3 promotes growth of gliomaCarcinogenesisFebruary 1, 2011Liu C, Luo D, Reynolds BA, Meher G, Katritzky AR, Lu B, Gerard CJ, Bhadha CP, Harrison JK.

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Recombinant Mouse CXCL10/IP-10/CRG-2 Protein from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Mouse CXCL10/IP-10/CRG-2 Protein from R&D Systems, a Bio-Techne Brand

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