Recombinant Human ErbB3/Her3 Fc Chimera Protein, CF 348-RB-050 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human ErbB3/Her3 Fc Chimera Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $465.00Supplier Page View Company Product Page
Catalog Number348-RB-050
SpeciesHuman
Size50 ug
FormatLyophilized from a 0.2 µm filtered solution in PBS
Molecule NameErbB3/Her3
NCBI Full Gene Nameerb-b2 receptor tyrosine kinase 3
NCBI Gene AliasesMDA-BF-1, LCCS2, p180-ErbB3, VSCN1, c-erbB3, p85-sErbB3, FERLK, erbB3-S, HER3, c-erbB-3, ErbB-3, p45-sErbB3
Purity>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 130-140 kDa, reducing conditions
Theoretical: 96 kDa (monomer)
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemNS0-derived Recombinant Human ErbB3/Her3 Fc Chimera Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Inhibition of HER Receptors Reveals Distinct Mechanisms of Compensatory Upregulation of Other HER Family Members: Basis for Acquired Resistance and for Combination TherapyCellsJanuary 29, 2021Gutsch D, Jenke R, Büch T, Aigner A.

(2) Soluble HER3 predicts survival in bladder cancer patientsOncology lettersFebruary 1, 2018Memon AA, Gilliver SC, Borre M, Sundquist J, Sundquist K, Nexo E, Sorensen BS.

(3) Evaluation of antibody fragment properties for near-infrared fluorescence imaging of HER3-positive cancer xenograftsTheranosticsJanuary 1, 2018El-Sayed A, Bernhard W, Barreto K, Gonzalez C, Hill W, Pastushok L, Fonge H, Geyer CR.

(4) Efficient generation of single domain antibodies with high affinities and enhanced thermal stabilitiesScientific reportsJuly 19, 2017Shinozaki N, Hashimoto R, Fukui K, Uchiyama S.

(5) Neuregulin 1 Allosterically Enhances the Antitumor Effects of the Noncompeting Anti-HER3 Antibody 9F7-F11 by Increasing Its Binding to HER3Molecular cancer therapeuticsJuly 1, 2017Le Clorennec C, Bazin H, Dubreuil O, Larbouret C, Ogier C, Lazrek Y, Garambois V, Poul MA, Mondon P, Barret JM, et al.

(6) Neuregulin-1 type III knockout mice exhibit delayed migration of Schwann cell precursorsBiochemical and biophysical research communicationsApril 29, 2017Miyamoto Y, Torii T, Tanoue A, Kawahara K, Arai M, Tsumura H, Ogata T, Nagao M, Terada N, Yamamoto M, et al.

(7) A Highly Diverse and Functional Naïve Ubiquitin Variant Library for Generation of Intracellular Affinity ReagentsJournal of molecular biologyJanuary 6, 2017Leung I, Jarvik N, Sidhu SS.

(8) A High-Affinity Repebody for Molecular Imaging of EGFR-Expressing Malignant TumorsTheranosticsJanuary 1, 2017Yun M, Kim DY, Lee JJ, Kim HS, Kim HS, Pyo A, Ryu Y, Kim TY, Zheng JH, Yoo SW, et al.

(9) A HER2-specific Modified Fc Fragment (Fcab) Induces Antitumor Effects Through Degradation of HER2 and ApoptosisMolecular therapy : the journal of the American Society of Gene TherapyNovember 1, 2015Leung KM, Batey S, Rowlands R, Isaac SJ, Jones P, Drewett V, Carvalho J, Gaspar M, Weller S, Medcalf M, et al.

(10) Identification of prolidase as a high affinity ligand of the ErbB2 receptor and its regulation of ErbB2 signaling and cell growthCell death & diseaseMay 8, 2014Yang L, Li Y, Zhang Y.Methods Reagents Recombinant chimeras, including human ErbB2/ECD-Fc (1129-ER-050), human ErbB3/ECD-Fc (348-RB-050) and human ErbB4/ECD-Fc (1131-ER-050) as well as recombinant Fc of human IgG1 (110-HG-100) were from

(11) Rapid optimization and prototyping for therapeutic antibody-like moleculesmAbsMarch 1, 2013Xu L, Kohli N, Rennard R, Jiao Y, Razlog M, Zhang K, Baum J, Johnson B, Tang J, Schoeberl B, et al.

(12) Design of an optimized scaffold for affibody moleculesJournal of molecular biologyApril 30, 2010Feldwisch J, Tolmachev V, Lendel C, Herne N, Sjöberg A, Larsson B, Rosik D, Lindqvist E, Fant G, Höidén-Guthenberg I, et al.

(13) Identification of neuregulin as a factor required for formation of aligned spermatogoniaThe Journal of biological chemistryJanuary 5, 2007Hamra FK, Chapman KM, Nguyen D, Garbers DL.

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Recombinant Human ErbB3/Her3 Fc Chimera Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human ErbB3/Her3 Fc Chimera Protein, CF from R&D Systems, a Bio-Techne Brand

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