Lefty-A Protein 746-LF-025 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemLefty-A Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $449.00Supplier Page View Company Product Page
Catalog Number746-LF-025
SpeciesHuman
Size25 ug
Molecule NameLefty-A
NCBI Full Gene Nameleft right determination factor 1, left-right determination factor 2
NCBI Gene AliasesEbaf, TGFB4, lefty-1, Stra3, lefty, EBAF, LEFTA, Leftb, Tgfb4, LEFTYA
FormatLyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein
Purity>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 44 kDa, 38 kDa and 34 kDa, reducing conditions
Theoretical: 39 kDa
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemNS0-derived Recombinant Human Lefty-A Protein
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

Available conjugates: Sizes Available: 25 ug

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

(2) PMN-MDSCs Enhance CTC Metastatic Properties through Reciprocal Interactions via ROS/Notch/Nodal SignalingInternational journal of molecular sciencesApril 18, 2019Sprouse ML, Welte T, Boral D, Liu HN, Yin W, Vishnoi M, Goswami-Sewell D, Li L, Pei G, Jia P, et al.

(3) Novel Regulatory Mechanisms for the SoxC Transcriptional Network Required for Visual Pathway DevelopmentThe Journal of neuroscience : the official journal of the Society for NeuroscienceMay 10, 2017Chang KC, Hertz J, Zhang X, Jin XL, Shaw P, Derosa BA, Li JY, Venugopalan P, Valenzuela DA, Patel RD, et al.

(4) LeftyA decreases Actin Polymerization and Stiffness in Human Endometrial Cancer CellsScientific reportsJuly 11, 2016Salker MS, Schierbaum N, Alowayed N, Singh Y, Mack AF, Stournaras C, Schäffer TE, Lang F.

(5) LEFTYA Activates the Epithelial Na+ Channel (ENaC) in Endometrial Cells via Serum and Glucocorticoid Inducible Kinase SGK1Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacologyJanuary 1, 2016Salker MS, Hosseinzadeh Z, Alowayed N, Zeng N, Umbach AT, Webster Z, Singh Y, Brosens JJ, Lang F.

(6) Role of Lefty in the anti tumor activity of human adult liver stem cellsOncogeneFebruary 14, 2013Cavallari C, Fonsato V, Herrera MB, Bruno S, Tetta C, Camussi G.

(7) Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitorsNatureJuly 26, 2012Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, Peng J, Lin E, Wang Y, Sosman J, et al.

(8) Deregulation of the serum- and glucocorticoid-inducible kinase SGK1 in the endometrium causes reproductive failureNature medicineOctober 16, 2011Salker MS, Christian M, Steel JH, Nautiyal J, Lavery S, Trew G, Webster Z, Al-Sabbagh M, Puchchakayala G, Föller M, et al.

(9) Activin a efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressedStem CellsJanuary 1, 2007McLean AB, D'Amour KA, Jones KL, Krishnamoorthy M, Kulik MJ, Reynolds DM, Sheppard AM, Liu H, Xu Y, Baetge EE, et al.

(10) Immunophenotypic clustering of myelodysplastic syndromesBloodOctober 1, 2002Maynadié M, Picard F, Husson B, Chatelain B, Cornet Y, Le Roux G, Campos L, Dromelet A, Lepelley P, Jouault H, et al.

(11) Nodal Signaling Regulates Germ Cell Development and Establishment of Seminiferous Cords in the Human Fetal TestisCell reportsJanuary 1, 0001"Jørgensen A, Macdonald J, Nielsen JE, Kilcoyne KR, Perlman S, Lundvall L, Langhoff Thuesen L, Juul Hare K, Frederiksen H, Andersson AM, et al."

Lefty-A Protein from R&D Systems, a Bio-Techne Brand