Recombinant Rat Agrin Protein, CF 550-AG-100/CF from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Rat Agrin Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $523.00Supplier Page View Company Product Page
Catalog Number550-AG-100/CF
SpeciesRat
FormatLyophilized from a 0.2 µm filtered solution in PBS
Size100 ug
Molecule NameAgrin
NCBI Full Gene Nameagrin
NCBI Gene AliasesAGR
Purity>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 100 kDa, reducing conditions
Theoretical: 90 kDa
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemSf 21 (baculovirus)-derived Recombinant Rat Agrin Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Localized release of muscle-generated BDNF regulates the initial formation of postsynaptic apparatus at neuromuscular synapsesCell Death & DifferentiationNovember 7, 2024Jinkai Zhang, Hiu-Lam Rachel Kwan, Chi Bun Chan, Chi Wai Leeinduce postsynaptic differentiation, polystyrene latex beads coated with recombinant agrin (R&D Systems, 550-AG-100/CF) or dissociated spinal neurons were added to 2 day-old muscle cultures as previously described [13,

(2) Nerve-independent formation of membrane infoldings at topologically complex postsynaptic apparatus by caveolin-3Science advancesJune 16, 2023Kwan HR, Chan ZC, Bi X, Kutkowska J, Prószyński TJ, Chan CB, Lee CW.co-cultures, dissociated spinal neurons or polystyrene latex beads coated with recombinant agrin (R&D Systems, 550-AG-100/CF) were added to 2-day-old muscle cultures and grown for the specified time before imaging as previously

(3) Neuronal Agrin Promotes Proliferation of Primary Human Myoblasts in an Age-Dependent MannerInternational journal of molecular sciencesOctober 4, 2022Gros K, Matkovič U, Parato G, Miš K, Luin E, Bernareggi A, Sciancalepore M, Marš T, Lorenzon P, Pirkmajer S.

(4) Control of CRK-RAC1 activity by the miR-1/206/133 miRNA family is essential for neuromuscular junction functionNature communicationsJune 8, 2022Klockner I, Schutt C, Gerhardt T, Boettger T, Braun T.

(5) Differential vulnerability of hippocampal CA3-CA1 synapses to AβActa neuropathologica communicationsApril 4, 2022Shipton OA, Tang CS, Paulsen O, Vargas-Caballero M.

(6) Involvement of neuronal and muscular Trk-fused gene (TFG) defects in the development of neurodegenerative diseasesScientific reportsFebruary 4, 2022Yamamotoya T, Hasei S, Akasaka Y, Ohata Y, Nakatsu Y, Kanna M, Fujishiro M, Sakoda H, Ono H, Kushiyama A, et al.

(7) Transport and Secretion of the Wnt3 Ligand by Motor Neuron-like Cells and Developing Motor NeuronsBiomoleculesDecember 17, 2021Pinto C, Pérez V, Mella J, Albistur M, Caprile T, Bronfman FC, Henríquez JP.

(8) Mechanism of disease and therapeutic rescue of Dok7 congenital myastheniaNatureJuly 1, 2021Oury J, Zhang W, Leloup N, Koide A, Corrado AD, Ketavarapu G, Hattori T, Koide S, Burden SJ.

(9) Activation of skeletal muscle-resident glial cells upon nerve injuryJCI insightApril 8, 2021Proietti D, Giordani L, De Bardi M, D'Ercole C, Lozanoska-Ochser B, Amadio S, Volonté C, Marinelli S, Muchir A, Bouché M, et al.

(10) Grp94 Regulates the Recruitment of Aneural AChR Clusters for the Assembly of Postsynaptic Specializations by Modulating ADF/Cofilin Activity and TurnovereNeuroSeptember 1, 2020Chan ZC, Deng L, Lee CW.coculture, dissociated spinal neurons or polystyrene latex beads coated with agrin (R&D Systems, catalog #550-AG-100/CF) were added in 2-d-old muscle cultures and maintained for 1 d before imaging. All the experiments involving

(11) Neuronal MT1-MMP mediates ECM clearance and Lrp4 cleavage for agrin deposition and signaling in presynaptic developmentJournal of cell scienceAugust 5, 2020Oentaryo MJ, Tse AC, Lee CW.

(12) Phosphorylation of α-dystrobrevin is essential for αkap accumulation and acetylcholine receptor stabilityThe Journal of biological chemistryJuly 31, 2020Chen PJ, Zelada D, Belhasan DC, Akaaboune M.

(13) A mechanism in agrin signaling revealed by a prevalent Rapsyn mutation in congenital myasthenic syndromeeLifeSeptember 24, 2019Xing G, Jing H, Zhang L, Cao Y, Li L, Zhao K, Dong Z, Chen W, Wang H, Cao R, et al.

(14) A Role of Agrin in Maintaining the Stability of Vascular Endothelial Growth Factor Receptor-2 during Tumor AngiogenesisCell reportsJuly 23, 2019Njah K, Chakraborty S, Qiu B, Arumugam S, Raju A, Pobbati AV, Lakshmanan M, Tergaonkar V, Thibault G, Wang X, et al.

(15) Characterization of pathogenic monoclonal autoantibodies derived from muscle-specific kinase myasthenia gravis patientsJCI insightJune 20, 2019Takata K, Stathopoulos P, Cao M, Mané-Damas M, Fichtner ML, Benotti ES, Jacobson L, Waters P, Irani SR, Martinez-Martinez P, et al.

(16) Cullin-3 dependent deregulation of ACTN1 represents a new pathogenic mechanism in nemaline myopathyJCI insightApril 16, 2019Blondelle J, Tallapaka K, Seto JT, Ghassemian M, Clark M, Laitila JM, Bournazos A, Singer JD, Lange S.

(17) Three-Dimensional Human iPSC-Derived Artificial Skeletal Muscles Model Muscular Dystrophies and Enable Multilineage Tissue EngineeringCell reportsApril 17, 2018Maffioletti SM, Sarcar S, Henderson ABH, Mannhardt I, Pinton L, Moyle LA, Steele-Stallard H, Cappellari O, Wells KE, Ferrari G, et al.

(18) Preserving neuromuscular synapses in ALS by stimulating MuSK with a therapeutic agonist antibodyeLifeFebruary 20, 2018Cantor S, Zhang W, Delestrée N, Remédio L, Mentis GZ, Burden SJ.

(19) Lack of Fgf18 causes abnormal clustering of motor nerve terminals at the neuromuscular junction with reduced acetylcholine receptor clustersScientific reportsJanuary 11, 2018Ito K, Ohkawara B, Yagi H, Nakashima H, Tsushima M, Ota K, Konishi H, Masuda A, Imagama S, Kiyama H, et al.

(20) Cullin E3 Ligase Activity Is Required for Myoblast DifferentiationJournal of molecular biologyApril 7, 2017Blondelle J, Shapiro P, Domenighetti AA, Lange S.

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Recombinant Rat Agrin Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Rat Agrin Protein, CF from R&D Systems, a Bio-Techne Brand

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