Recombinant Human CD14 Protein, CF 383-CD-050/CF from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human CD14 Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $412.00Supplier Page View Company Product Page
Catalog Number383-CD-050/CF
Size50 ug
ApplicationsBioactivity
FormatLyophilized from a 0.2 µm filtered solution in PBS
Purity>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 43-58 kDa, reducing conditions
Theoretical: 35.8 kDa
Conjugate/TagUnconjugated
SpeciesHuman
Molecule NameCD14
Source/Expression SystemCHO-derived Recombinant Human CD14 Protein, CF
NCBI Full Gene NameCD14 molecule
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

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(2) The soluble cytoplasmic tail of CD45 regulates T-cell activation via TLR4 signalingEuropean journal of immunologyDecember 1, 2021Puck A, Künig S, Modak M, May L, Fritz P, Battin C, Radakovics K, Steinberger P, Reipert BM, Crowe BA, et al.

(3) Immunologic biomarkers, morbidity and mortality among HIV patients hospitalised in a Tertiary Care Hospital in the Brazilian AmazonBMC infectious diseasesAugust 26, 2021Gama WM, Frank CHM, Almeida TVR, Dos Santos DS, Chaves YO, da Silva DF, Orlandi PP, Pereira FR, Magalhães GF, Baptista BJ, et al.

(4) HIV-1 Tat - TLR4/MD2 interaction drives the expression of IDO-1 in monocytes derived dendritic cells through NF-κB dependent pathwayScientific reportsMay 18, 2020Bahraoui E, Serrero M, Planès R.

(5) Inorganic polyphosphate potentiates lipopolysaccharide-induced macrophage inflammatory responseThe Journal of biological chemistryMarch 20, 2020Ito T, Yamamoto S, Yamaguchi K, Sato M, Kaneko Y, Goto S, Goto Y, Narita I.

(6) Role of TLR4 Receptor Complex in the Regulation of the Innate Immune Response by FibronectinCellsJanuary 15, 2020Zheng M, Ambesi A, McKeown-Longo PJ.

(7) Tie2 protects the vasculature against thrombus formation in systemic inflammationThe Journal of clinical investigationApril 2, 2018Higgins SJ, De Ceunynck K, Kellum JA, Chen X, Gu X, Chaudhry SA, Schulman S, Libermann TA, Lu S, Shapiro NI, et al.

(8) Estradiol alters the immune-responsiveness of cervical epithelial cells stimulated with ligands of Toll-like receptors 2 and 4PloS oneJanuary 1, 2017S Lashkari B, Anumba DO.

(9) Granzymes A and K differentially potentiate LPS-induced cytokine responseCell death discoveryJanuary 1, 2016Wensink AC, Kok HM, Meeldijk J, Fermie J, Froelich CJ, Hack CE, Bovenschen N.

(10) CD14 Is a Co-Receptor for TLR4 in the S100A9-Induced Pro-Inflammatory Response in MonocytesPloS oneJanuary 1, 2016He Z, Riva M, Björk P, Swärd K, Mörgelin M, Leanderson T, Ivars F.through standard amine coupling. Then recombinant human CD14, derived from CHO cells (R&D Systems cat no 383-CD-050/CF), was injected (for 2 min at a flow rate of 30 μl/min) in 10 mM HEPES, 0.15 M NaCl, pH 7.4, containing

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(12) Recombinant thrombomodulin inhibits lipopolysaccharide-induced inflammatory response by blocking the functions of CD14Journal of immunology (Baltimore, Md. : 1950)February 15, 2015Ma CY, Chang WE, Shi GY, Chang BY, Cheng SE, Shih YT, Wu HL.

(13) Plasticity-related gene 5 promotes spine formation in murine hippocampal neuronsThe Journal of biological chemistrySeptember 5, 2014Coiro P, Stoenica L, Strauss U, Bräuer AU.

(14) Directed evolution of an LBP/CD14 inhibitory peptide and its anti-endotoxin activityPloS oneJanuary 1, 2014Fang L, Xu Z, Wang GS, Ji FY, Mei CX, Liu J, Wu GM.

(15) Proteasome proteolysis supports stimulated platelet function and thrombosisArteriosclerosis, thrombosis, and vascular biologyJanuary 1, 2014Gupta N, Li W, Willard B, Silverstein RL, McIntyre TM.

(16) Outer membrane vesicles derived from Escherichia coli up-regulate expression of endothelial cell adhesion molecules in vitro and in vivoPloS oneJanuary 1, 2013Kim JH, Yoon YJ, Lee J, Choi EJ, Yi N, Park KS, Park J, Lötvall J, Kim YK, Gho YS.

(17) E-selectin mediated adhesion and migration of endothelial colony forming cells is enhanced by SDF-1α/CXCR4PloS oneJanuary 1, 2013Sun J, Li Y, Graziani GM, Filion L, Allan DS.

(18) Cd14 SNPs regulate the innate immune responseMolecular ImmunologyJune 1, 2012Hong-Hsing Liu et al.re-suspended in DC stimulation media in the presence or absence of 1–5 ug/ml sCD14 (R&D Systems, cat# 383-CD-050-CF) at 1 × 106 cells/ml overnight at 37°C/10%CO2. The DC stimulation media contained different TLR agonists

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(20) Iris pigment epithelial cells express a functional lipopolysaccharide receptor complexInvestigative ophthalmology & visual scienceMay 1, 2010Chui JJ, Li MW, Di Girolamo N, Chang JH, McCluskey PJ, Wakefield D.

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(1)

4/16/2019383-CD (CD14) Prevents LPS Binding to TLR4 Anonymous ReviewThe protein shows desired binding interactions and neutralizes TLR4 interactions with LPS.

Recombinant Human CD14 Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human CD14 Protein, CF from R&D Systems, a Bio-Techne Brand

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