Recombinant Human CTLA-4 Fc Chimera His-tag Protein 325-CT-200 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human CTLA-4 Fc Chimera His-tag Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $504.00Supplier Page View Company Product Page
Catalog Number325-CT-200
SpeciesHuman
Size200 ug
Molecule NameCTLA-4
FormatLyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein
Purity>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular Weight40 kDa (monomer)
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemSf 21 (baculovirus)-derived Recombinant Human CTLA-4 Fc Chimera His-tag Protein
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Full Gene Namecytotoxic T-lymphocyte associated protein 4
NCBI Gene AliasesALPS5, CD, CD152, CELIAC3, CTLA-4, GRD4, GSE, IDDM12

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) CD25(+)FOXP3(+)CD45RA(-) regulatory T-cell infiltration as a prognostic biomarker for endometrial carcinomaBMC cancerSeptember 4, 2024Suto A, Minaguchi T, Qi N, Fujieda K, Itagaki H, Tenjimbayashi Y, Shikama A, Tasaka N, Akiyama A, Nakao S, et al.

(2) TCR ligand potency differentially impacts PD-1 inhibitory effects on diverse signaling pathwaysThe Journal of experimental medicineDecember 4, 2023Chan W, Cao YM, Zhao X, Schrom EC, Jia D, Song J, Sibener LV, Dong S, Fernandes RA, Bradfield CJ, et al.clone MIH1 (53-5983-42; Thermo Fisher Scientific), and recombinant human CTLA-4 Fc chimera protein (325-CT-200; R&D Systems) in combination with APC-labeled mouse anti-human IgG Fc antibodies (FAB110A; R&D Systems). Stimulation

(3) Idelalisib and caffeine reduce suppression of T cell responses mediated by activated chronic lymphocytic leukemia cellsPloS oneJanuary 1, 2017Hock BD, MacPherson SA, McKenzie JL.

(4) Cell-extrinsic CTLA4-mediated regulation of dendritic cell maturation depends on STAT3European journal of immunologyApril 1, 2014Kowalczyk A, D'Souza CA, Zhang L.

(5) MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancersNatureMarch 17, 2011Steidl C, Shah SP, Woolcock BW, Rui L, Kawahara M, Farinha P, Johnson NA, Zhao Y, Telenius A, Neriah SB, et al.

(6) Human gammadelta T lymphocytes induce robust NK cell-mediated antitumor cytotoxicity through CD137 engagementBloodSeptember 9, 2010Maniar A, Zhang X, Lin W, Gastman BR, Pauza CD, Strome SE, Chapoval AI.

(7) Lung myeloid dendritic cells coordinately induce TH1 and TH17 responses in human emphysemaScience translational medicineOctober 28, 2009Shan M, Cheng HF, Song LZ, Roberts L, Green L, Hacken-Bitar J, Huh J, Bakaeen F, Coxson HO, Storness-Bliss C, et al.

(8) The soluble forms of CD28, CD86 and CTLA-4 constitute possible immunological markers in patients with abdominal aortic aneurysmJournal of internal medicineApril 1, 2007Sakthivel P, Shively V, Kakoulidou M, Pearce W, Lefvert AK.

(9) Activity and Safety of CTLA-4 Blockade Combined with Vaccines in Cynomolgus MacaquesThe Journal of ImmunologyDecember 1, 2003Tibor Keler et al.extracellular CTLA-4 fragment was prepared by proteolytic cleavage of the CTLA-4/Fc fusion protein (cat. no. 325-CT-200; R&D Systems) at a factor Xa protease cleavage site located after the C terminus of the CTLA-4 extracellular

(10) Chimeric co-stimulatory molecules that selectively act through CD28 or CTLA-4 on human T cellsThe Journal of biological chemistryOctober 11, 2002Lazetic S, Leong SR, Chang JC, Ong R, Dawes G, Punnonen J.

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CTLA-4 Fc Chimera Protein

CTLA-4 Fc Chimera Protein

CTLA-4 Fc Chimera Protein

CTLA-4 Fc Chimera Protein

Recombinant Human CTLA-4 Fc Chimera His-tag Protein from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human CTLA-4 Fc Chimera His-tag Protein from R&D Systems, a Bio-Techne Brand

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