Recombinant Mouse CCL11/Eotaxin Protein 420-ME-020 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Mouse CCL11/Eotaxin Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $312.00Supplier Page View Company Product Page
Catalog Number420-ME-020
SpeciesMouse
Molecule NameCCL11/Eotaxin
Size20 ug (also 100 ug)
NCBI Full Gene Namechemokine (C-C motif) ligand 11
NCBI Gene AliasesScya11, eotaxin
FormatLyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein
Purity>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular Weight8.4 kDa
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemE. coli-derived Recombinant Mouse CCL11/Eotaxin Protein
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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(1) Reduced ccl11/eotaxin mediates the beneficial effects of environmental stimulation on the aged hippocampusBrain, behavior, and immunityNovember 1, 2021Scabia G, Testa G, Scali M, Del Turco S, Desiato G, Berardi N, Sale A, Matteoli M, Maffei L, Maffei M, et al.

(2) Muscle Stem Cells Give Rise to Rhabdomyosarcomas in a Severe Mouse Model of Duchenne Muscular DystrophyCell reportsJanuary 15, 2019Boscolo Sesillo F, Fox D, Sacco A.in 96 wells plates and treated either with 100 ng/mL of Ccl11 recombinant protein (catalog number: 420-ME-020, R&D Systems) or with 50 ng/mL of Flt3l recombinant protein (catalog number: 427-FL-005, R&D Systems).

(3) CCL11, a novel mediator of inflammatory bone resorptionScientific reportsJuly 13, 2017Kindstedt E, Holm CK, Sulniute R, Martinez-Carrasco I, Lundmark R, Lundberg P.

(4) Rapid transport of CCL11 across the blood-brain barrier: regional variation and importance of blood cellsThe Journal of pharmacology and experimental therapeuticsJune 1, 2014Erickson MA, Morofuji Y, Owen JB, Banks WA.

(5) The ageing systemic milieu negatively regulates neurogenesis and cognitive functionNatureAugust 31, 2011Villeda SA, Luo J, Mosher KI, Zou B, Britschgi M, Bieri G, Stan TM, Fainberg N, Ding Z, Eggel A, et al.

(6) Impaired basophil induction leads to an age-dependent innate defect in type 2 immunity during helminth infection in miceJournal of immunology (Baltimore, Md. : 1950)April 15, 2011Nel HJ, Hams E, Saunders SP, Mangan NE, Smith P, Atzberger A, Flavell RA, Akira S, McKenzie AN, Fallon PG.

(7) Resolution of allergic inflammation and airway hyperreactivity is dependent upon disruption of the T1/ST2-IL-33 pathwayAmerican journal of respiratory and critical care medicineMay 1, 2009Kearley J, Buckland KF, Mathie SA, Lloyd CM.

(9) Sequential ELISA to profile multiple cytokines from small volumesJournal of immunological methodsJuly 1, 2005Osuchowski MF, Siddiqui J, Copeland S, Remick DG.

(10) Discovery of CC chemokine receptor-3 (CCR3) antagonists with picomolar potencyJournal of medicinal chemistryMarch 24, 2005De Lucca GV, Kim UT, Vargo BJ, Duncia JV, Santella JB 3rd, Gardner DS, Zheng C, Liauw A, Wang Z, Emmett G, et al.

(11) The role of CCL21 in recruitment of T-precursor cells to fetal thymiBloodJanuary 1, 2005Liu C, Ueno T, Kuse S, Saito F, Nitta T, Piali L, Nakano H, Kakiuchi T, Lipp M, Hollander GA, et al.

(13) P-selectin mediates IL-13-induced eosinophil transmigration but not eotaxin generation in vivo: a comparative study with IL-4-elicited responsesJournal of leukocyte biologyJanuary 1, 2003Larbi KY, Dangerfield JP, Culley FJ, Marshall D, Haskard DO, Jose PJ, Williams TJ, Nourshargh S.

(14) Identification of full, partial and inverse CC chemokine receptor 3 agonists using [35S]GTPgammaS bindingEuropean journal of pharmacologyDecember 5, 2002Wan Y, Jakway JP, Qiu H, Shah H, Garlisi CG, Tian F, Ting P, Hesk D, Egan RW, Billah MM, et al.

(15) AMD3100, a CxCR4 antagonist, attenuates allergic lung inflammation and airway hyperreactivityThe American journal of pathologyApril 1, 2002Lukacs NW, Berlin A, Schols D, Skerlj RT, Bridger GJ.

Recombinant Mouse CCL11/Eotaxin Protein from R&D Systems, a Bio-Techne Brand