Recombinant Human Ephrin-A3 Fc Chimera Protein, CF 359-EA-200 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human Ephrin-A3 Fc Chimera Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $373.00Supplier Page View Company Product Page
Catalog Number359-EA-200
SpeciesHuman
FormatLyophilized from a 0.2 µm filtered solution in PBS
Molecule NameEphrin-A3
Size200 ug
Purity>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 60-70 kDa, reducing conditions
Theoretical: 47.7 kDa (monomer)
ApplicationsBinding Activity
Conjugate/TagUnconjugated
Source/Expression SystemNS0-derived Recombinant Human Ephrin-A3 Fc Chimera Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Full Gene Nameephrin A3
NCBI Gene AliasesEFL2, EPLG3, Ehk1-L, LERK3

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Ephrin-A3 is required for tonotopic map precision and auditory functions in the mouse auditory brainstemThe Journal of comparative neurologyNovember 1, 2021Hoshino N, Altarshan Y, Alzein A, Fernando AM, Nguyen HT, Majewski EF, Chen VC, Rochlin MW, Yu WM.first stripe solutions contained 2–40 μg/ml recombinant ephrin-A3-Fc chimera protein (R&D Systems, 359-EA-200) (human IgG-Fc was added together with 2–20 μg/ml ephrin-A3-Fc to fill in the concentration to 40 μg/ml).

(2) Ephrin A4-ephrin receptor A10 signaling promotes cell migration and spheroid formation by upregulating NANOG expression in oral squamous cell carcinoma cellsScientific reportsJanuary 12, 2021Chen YL, Yen YC, Jang CW, Wang SH, Huang HT, Chen CH, Hsiao JR, Chang JY, Chen YW.

(3) Structural and functional analyses reveal promiscuous and species specific use of ephrin receptors by Cedar virusProceedings of the National Academy of Sciences of the United States of AmericaOctober 8, 2019Laing ED, Navaratnarajah CK, Cheliout Da Silva S, Petzing SR, Xu Y, Sterling SL, Marsh GA, Wang LF, Amaya M, Nikolov DB, et al.

(4) Point mutations in dimerization motifs of the transmembrane domain stabilize active or inactive state of the EphA2 receptor tyrosine kinaseThe Journal of biological chemistryMay 23, 2014Sharonov GV, Bocharov EV, Kolosov PM, Astapova MV, Arseniev AS, Feofanov AV.

(5) Attenuation of eph receptor kinase activation in cancer cells by coexpressed ephrin ligandsPloS oneJanuary 1, 2013Falivelli G, Lisabeth EM, Rubio de la Torre E, Perez-Tenorio G, Tosato G, Salvucci O, Pasquale EB.

(6) Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitorsNatureJuly 26, 2012Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, Peng J, Lin E, Wang Y, Sosman J, et al.

(7) Astrocyte-produced ephrins inhibit schwann cell migration via VAV2 signalingThe Journal of neuroscience : the official journal of the Society for NeuroscienceMarch 24, 2010Afshari FT, Kwok JC, Fawcett JW.

(8) Synaptic activity prompts gamma-secretase-mediated cleavage of EphA4 and dendritic spine formationThe Journal of cell biologyMay 4, 2009Inoue E, Deguchi-Tawarada M, Togawa A, Matsui C, Arita K, Katahira-Tayama S, Sato T, Yamauchi E, Oda Y, Takai Y.

(9) Plasticity of neuron-glial interactions mediated by astrocytic EphARsThe Journal of neuroscience : the official journal of the Society for NeuroscienceNovember 21, 2007Nestor MW, Mok LP, Tulapurkar ME, Thompson SM.

(10) Control of hippocampal dendritic spine morphology through ephrin-A3/EphA4 signalingNature neuroscienceFebruary 1, 2003Murai KK, Nguyen LN, Irie F, Yamaguchi Y, Pasquale EB.

(11) Ephrin stimulation modulates T cell chemotaxisEuropean journal of immunologyDecember 1, 2002Sharfe N, Freywald A, Toro A, Dadi H, Roifman C.

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Recombinant Human Ephrin-A3 Fc Chimera Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human Ephrin-A3 Fc Chimera Protein, CF from R&D Systems, a Bio-Techne Brand

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