Recombinant Mouse B7-1/CD80 Fc Chimera His-tag Protein, CF 740-B1-100 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Mouse B7-1/CD80 Fc Chimera His-tag Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $454.00Supplier Page View Company Product Page
Catalog Number740-B1-100
SpeciesMouse
Molecule NameB7-1/CD80
FormatLyophilized from a 0.2 µm filtered solution in PBS
Size100 ug (also 1 mg)
NCBI Full Gene NameCD80 antigen
NCBI Gene AliasesB71, Ly53, Ly-53, MIC17, TSA1, Cd28l
Purity>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 80-90 kDa, reducing conditions
Theoretical: 51.3 kDa (monomer)
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemNS0-derived Recombinant Mouse B7-1/CD80 Fc Chimera His-tag Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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(1) Aire suppresses CTLA-4 expression from the thymic stroma to control autoimmunityCell reportsFebruary 15, 2022Morimoto J, Matsumoto M, Miyazawa R, Yoshida H, Tsuneyama K, Matsumoto M.

(2) Dual and Opposite Costimulatory Targeting with a Novel Human Fusion Recombinant Protein Effectively Prevents Renal Warm Ischemia Reperfusion Injury and Allograft Rejection in Murine ModelsInternational journal of molecular sciencesJanuary 26, 2021Guiteras J, De Ramon L, Crespo E, Bolaños N, Barcelo-Batllori S, Martinez-Valenzuela L, Fontova P, Jarque M, Torija A, Bestard O, et al.

(3) Activity of murine surrogate antibodies for durvalumab and tremelimumab lacking effector function and the ability to deplete regulatory T cells in mouse models of cancermAbsJanuary 1, 2021Schofield DJ, Percival-Alwyn J, Rytelewski M, Hood J, Rothstein R, Wetzel L, McGlinchey K, Adjei G, Watkins A, Machiesky L, et al.catalog #1021-PE-100), recombinant mouse B7-1/CD80 Fc chimera His-tag protein (R&D Systems, catalog #740-B1-100), and purified anti-mouse PD-L1 clone 10 F.9G2 (BioLegend, catalog #124302) were conjugated with DyLight-650

(4) Self-Assembled Multivalent Aptamer Nanoparticles with Potential CAR-like Characteristics Could Activate T Cells and Inhibit Melanoma GrowthMolecular therapy oncolyticsJune 26, 2020Bai C, Gao S, Hu S, Liu X, Li H, Dong J, Huang A, Zhu L, Zhou P, Li S, et al.anti-CD3 antibodies (0.025 μg/well) and anti-CD28 antibodies (0.5 μg/well), B7.1 protein (R&D systems, 740-B1-100; 400 ng/well) was added to inhibit T cell proliferation before aptamers (200 pmol/well) or anti-CTLA-4

(8) Soluble production of a biologically active single-chain antibody against murine PD-L1 in Escherichia coliProtein expression and purificationFebruary 1, 2014Drees JJ, Augustin LB, Mertensotto MJ, Schottel JL, Leonard AS, Saltzman DA.

(11) B7-1 and B7-2 selectively recruit CTLA-4 and CD28 to the immunological synapseImmunitySeptember 1, 2004Pentcheva-Hoang T, Egen JG, Wojnoonski K, Allison JP.

(12) Cooperative B7-1/2 (CD80/CD86) and B7-DC costimulation of CD4+ T cells independent of the PD-1 receptorThe Journal of experimental medicineJuly 7, 2003Shin T, Kennedy G, Gorski K, Tsuchiya H, Koseki H, Azuma M, Yagita H, Chen L, Powell J, Pardoll D, et al.

Recombinant Mouse B7-1/CD80 Fc Chimera His-tag Protein, CF from R&D Systems, a Bio-Techne Brand