IL-11 Protein 218-IL-005/CF from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIL-11 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $351.00Supplier Page View Company Product Page
Catalog Number218-IL-005/CF
SpeciesHuman
Molecule NameIL-11
Source/Expression SystemSf 21 (baculovirus)-derived Recombinant Human IL-11 Protein, CF
Size5 ug (also 25 ug)
FormatSupplied as a 0.2 µm filtered solution in PBS and EDTA
NCBI Full Gene Nameinterleukin 11
NCBI Gene AliasesAGIF, IL-11
Purity>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 23 kDa, reducing conditions
Theoretical: 19 kDa
ApplicationsBioactivity
Conjugate/TagUnconjugated
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, 2 to 8 °C as supplied

Available conjugates: Sizes Available: 5 ug (also 25 ug)

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

(1) Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosisEBioMedicineDecember 1, 2022Xu S, Yang X, Chen Q, Liu Z, Chen Y, Yao X, Xiao A, Tian J, Xie L, Zhou M, et al.

(3) Modeling of Fibrotic Lung Disease Using 3D Organoids Derived from Human Pluripotent Stem CellsCell reportsJune 18, 2019Strikoudis A, Cieślak A, Loffredo L, Chen YW, Patel N, Saqi A, Lederer DJ, Snoeck HW.

(4) Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate DependenciesCell reportsApril 9, 2019Mair B, Tomic J, Masud SN, Tonge P, Weiss A, Usaj M, Tong AHY, Kwan JJ, Brown KR, Titus E, et al.

(5) KDM3A histone demethylase functions as an essential factor for activation of JAK2-STAT3 signaling pathwayProceedings of the National Academy of Sciences of the United States of AmericaNovember 13, 2018Kim H, Kim D, Choi SA, Kim CR, Oh SK, Pyo KE, Kim J, Lee SH, Yoon JB, Zhang Y, et al.

(6) BMTP-11 is active in preclinical models of human osteosarcoma and a candidate targeted drug for clinical translationProceedings of the National Academy of Sciences of the United States of AmericaJuly 25, 2017Lewis VO, Devarajan E, Cardó-Vila M, Thomas DG, Kleinerman ES, Marchiò S, Sidman RL, Pasqualini R, Arap W.

(7) Functional interleukin-33 receptors are expressed in early progenitor stages of allergy-related granulocytesImmunologyJanuary 1, 2017Tsuzuki H, Arinobu Y, Miyawaki K, Takaki A, Ota SI, Ota Y, Mitoma H, Akahoshi M, Mori Y, Iwasaki H, et al.

(8) A Novel Small-Molecule Inhibitor Targeting the IL-6 Receptor β Subunit, Glycoprotein 130Journal of immunology (Baltimore, Md. : 1950)July 1, 2015Hong SS, Choi JH, Lee SY, Park YH, Park KY, Lee JY, Kim J, Gajulapati V, Goo JI, Singh S, et al.

(9) IL-11 Induces Th17 Cell Responses in Patients with Early Relapsing-Remitting Multiple SclerosisJournal of immunology (Baltimore, Md. : 1950)June 1, 2015Zhang X, Tao Y, Chopra M, Dujmovic-Basuroski I, Jin J, Tang Y, Drulovic J, Markovic-Plese S.

(10) MTA2 enhances colony formation and tumor growth of gastric cancer cells through IL-11BMC cancerMay 2, 2015Zhou C, Ji J, Cai Q, Shi M, Chen X, Yu Y, Zhu Z, Zhang J.

(12) Vascular niche promotes hematopoietic multipotent progenitor formation from pluripotent stem cellsThe Journal of clinical investigationMarch 2, 2015Gori JL, Butler JM, Chan YY, Chandrasekaran D, Poulos MG, Ginsberg M, Nolan DJ, Elemento O, Wood BL, Adair JE, et al.

(13) Regulation of IL-17A responses in human airway smooth muscle cells by Oncostatin MRespiratory researchFebruary 7, 2015Kwofie K, Scott M, Rodrigues R, Guerette J, Radford K, Nair P, Richards CD.

(14) Endothelial cells translate pathogen signals into G-CSF-driven emergency granulopoiesisBloodAugust 28, 2014Boettcher S, Gerosa RC, Radpour R, Bauer J, Ampenberger F, Heikenwalder M, Kopf M, Manz MG.

(15) Autocrine production of IL-11 mediates tumorigenicity in hypoxic cancer cellsThe Journal of clinical investigationApril 1, 2013Onnis B, Fer N, Rapisarda A, Perez VS, Melillo G.

(16) Interferon-gamma reverses the immunosuppressive and protumoral properties and prevents the generation of human tumor-associated macrophagesInternational journal of cancerJuly 15, 2009Duluc D, Corvaisier M, Blanchard S, Catala L, Descamps P, Gamelin E, Ponsoda S, Delneste Y, Hebbar M, Jeannin P.

(18) Virally mediated MafB transduction induces the monocyte commitment of human CD34+ hematopoietic stem/progenitor cellsCell death and differentiationOctober 1, 2006Gemelli C, Montanari M, Tenedini E, Zanocco Marani T, Vignudelli T, Siena M, Zini R, Salati S, Tagliafico E, Manfredini R, et al.

(20) IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathwaysJournal of immunology (Baltimore, Md. : 1950)September 1, 2004Kao CY, Chen Y, Thai P, Wachi S, Huang F, Kim C, Harper RW, Wu R.

IL-11 Protein