17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid from Cayman Chemical

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17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid

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Description

A metabolite of lipoxygenase-mediated oxidation of DPA; activates Nrf2-dependent antioxidant gene expression, acts as a PPARγ agonist (EC50 = ~200 nM), and inhibits pro-inflammatory cytokine and nitric oxide production at biological concentration ranges (5-25 µM)