Description
Apolipoprotein B is the dominant protein constituent of LDL. Apo B in normal plasma is 90 mg/dl. Apo B is thought to stabilize lipid emulsions, serve as a cofactor and modulator of enzymatic reactions, manage export of lipids out of cells and direct lipids to target organs. Apo B levels are positively correlated with the risk of coronary disease. Apo B levels may be a more sensitive predictor of cardiovascular risk than LDL levels and do not involve fasting for accurate measurement. Two forms of Apo B exist: Apo B-100 and Apo B-48. The 1st is found in VLDL and LDL and produced by the liver. The 2nd found in chylomicrons, originates in the intestine