Caspase-10 Inhibitor Z-AEVD-FMK from R&D Systems, a Bio-Techne Brand

Product Specs
ItemCaspase-10 Inhibitor Z-AEVD-FMK
CompanyR&D Systems, a Bio-Techne Brand
Price $319.00Supplier Page View Company Product Page
Catalog NumberFMK009
NCBI Full Gene Namecaspase 10
NCBI Gene AliasesALPS2, FLICE-2, FLICE2, MCH4
StorageStore the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date
SpeciesMulti-Species
TypePeptides
Quantity1 mg

Specifications/Features

Available conjugates: Sizes Available: 1 mg

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) HOXC8 impacts lung tumorigenesis by preventing pyroptotic cell death through the suppression of caspase-1 expressionCell death & diseaseJuly 23, 2025Padia R, Sun L, Liao YF, Calbay O, Chi C, Akter M, Wu L, Fu Z, Zhang DD, Huang S.

(2) Integrated stress response (ISR) activation and apoptosis through HRI kinase by PG3 and other p53 pathway-restoring cancer therapeuticsOncotargetSeptember 17, 2024Tian X, El-Deiry WS.

(3) TRAF3/p38-JNK Signalling Crosstalk with Intracellular-TRAIL/Caspase-10-Induced Apoptosis Accelerates ROS-Driven Cancer Cell-Specific Death by CD40CellsOctober 18, 2022Ibraheem K, Yhmed AMA, Nasef MM, Georgopoulos NT.

(4) Cell Death Triggers Induce MLKL Cleavage in Multiple Myeloma Cells, Which may Promote Cell DeathFrontiers in oncologyJanuary 1, 2022Chen J, Wang S, Blokhuis B, Ruijtenbeek R, Garssen J, Redegeld F.Caspase-3 inhibitor Z-DEVD-FMK (FMK004), caspase-8 inhibitor Z-IETD-FMK (FMK007), caspase-10 inhibitor Z-AEVD-FMK (FMK009) and MG132 (1748) were obtained from R&D systems. Bis(sulfosuccinimidyl) suberate (BS3) (21586) were

(5) Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancerCellJanuary 14, 2021Elizabeth A. Bowling et al.2018",N/A Z-VAD-FMK,R&D Systems,Cat#FMK001 Z-IETD-FMK,R&D Systems,Cat#FMK007 Z-AEVD-FMK,R&D Systems,Cat#FMK009 Z-LEHD-FMK,R&D Systems,Cat#FMK008 RNase III,Applied Biosystems,Cat#A2290 RNaseOne,Promega,Cat#M4261 SuperScript

(6) The mechanism of how CD95/Fas activates the Type I IFN/STAT1 axis, driving cancer stemness in breast cancerScientific reportsJanuary 28, 2020Qadir AS, Stults AM, Murmann AE, Peter ME.caspase-8 inhibitor zIETD (FMK007), caspase-9 inhibitor zLEHD (FMK008) and caspase-10 inhibitor zAEVD (FMK009) were from R&D Systems. zVAD-fmk (BML-P416) was from Enzo Lifesciences. All caspase inhibitors were

(7) Bacterial Pore-Forming Toxins Promote the Activation of Caspases in Parallel to Necroptosis to Enhance Alarmin Release and Inflammation During PneumoniaScientific reportsApril 11, 2018Gonzalez-Juarbe N, Bradley KM, Riegler AN, Reyes LF, Brissac T, Park SS, Restrepo MI, Orihuela CJ.

(8) Reciprocal amplification of caspase-3 activity by nuclear export of a putative human RNA-modifying protein, PUS10 during TRAIL-induced apoptosisCell death & diseaseOctober 5, 2017Jana S, Hsieh AC, Gupta R.FMK004), -6 (Z-VEID-FMK, FMK006), -8 (Z-IETD-FMK, FMK007), -9 (Z-LEHD-FMK, FMK008) and -10 (Z-AEVD-FMK, FMK009). Immunofluorescence studies Cells were grown on coverslips placed in 60-mm plates and experiments

(9) Synergistic Antitumour Properties of viscumTT in Alveolar RhabdomyosarcomaJournal of immunology researchJanuary 1, 2017Stammer RM, Kleinsimon S, Rolff J, Jäger S, Eggert A, Seifert G, Delebinski CI.

(10) Lipopolysaccharide (LPS) Promotes Apoptosis in Human Breast Epithelial × Breast Cancer Hybrids, but Not in Parental CellsPloS oneJanuary 1, 2016Fried S, Tosun S, Troost G, Keil S, Zaenker KS, Dittmar T.

(11) Inhibition of cancer cell proliferation and apoptosis-inducing activity of fungal taxol and its precursor baccatin III purified from endophytic Fusarium solaniCancer cell internationalOctober 23, 2013Chakravarthi BV, Sujay R, Kuriakose GC, Karande AA, Jayabaskaran C.

(12) Brahma is essential for Drosophila intestinal stem cell proliferation and regulated by Hippo signalingeLifeOctober 15, 2013Jin Y, Xu J, Yin MX, Lu Y, Hu L, Li P, Zhang P, Yuan Z, Ho MS, Ji H, et al.

(13) Zoledronic acid significantly enhances radiation‑induced apoptosis against human fibrosarcoma cells by inhibiting radioadaptive signalingInternational journal of oncologyFebruary 1, 2013Koto K, Murata H, Kimura S, Sawai Y, Horie N, Matsui T, Ryu K, Ashihara E, Maekawa T, Kubo T, et al.

(14) Caspase-10 Is the Key Initiator Caspase Involved in Tributyltin-Mediated Apoptosis in Human Immune CellsJournal of ToxicologyJanuary 12, 2012Harald F. KrugPI and Hoechst 33342 from Sigma (Deisenhofen, Germany), and the inhibitors of caspase-10 (zAEVD-fmk; FMK009), caspase-9 (zLEHD-fmk; FMK008), and caspase3 (zDEVD-fmk; FMK004) were from R&D Systems (Wiesbaden,

(15) Disruption of occludin function in polarized epithelial cells activates the extrinsic pathway of apoptosis leading to cell extrusion without loss of transepithelial resistanceBMC Cell BiologyDecember 9, 2009Neal E Beeman, Heidi K Baumgartner, Patricia G Webb, Jerome B Schaack, Margaret C Neville100 μM, caspase 8 inhibitor (Z-IETD-FMK Cat.#FMK007), 50 μM, or caspase 10 inhibitor (Z-AEVD-FMK Cat.#FMK009) (R&D systems), 50 μM, was dissolved in medium and incubated with cells for 2 h. LYHY peptide was then

(16) Phosphatidylinositol 3-kinase/Akt signaling mediates interleukin-6 protection against p53-induced apoptosis in M1 myeloid leukemic cellsOncogeneMay 10, 2007Vesely DL, Hoffman B, Liebermann DA.caspase 9 inhibitor Z-LEHD-FMK (R&D Systems, cat. no. FMK008); and caspase 10 inhibitor Z-AEVD-FMK (R&D Systems, cat. no. FMK009). Antagonistic Fas/CD95 pathway blocking antibody was CD95 Fas clone ZB4 monoclonal antibody (blocking)

(17) HIV-1 tat protein and cell proliferation and survival: a brief reviewThe new microbiologicaApril 1, 2005Gibellini D, Vitone F, Schiavone P, Re MC.

(18) Increased sensitivity of early apoptotic cells to complement-mediated lysisEuropean journal of immunologyNovember 1, 2004Attali G, Gancz D, Fishelson Z.

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Caspase-10 Inhibitor Z-AEVD-FMK from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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Caspase-10 Inhibitor Z-AEVD-FMK from R&D Systems, a Bio-Techne Brand

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