15-deoxy-Δ12,14-Prostaglandin J2 18570 from Cayman Chemical

Product Specs
Item15-deoxy-Δ12,14-Prostaglandin J2
CompanyCayman Chemical
Price $578.00Supplier Page View Company Product Page
Catalog Number18570
Size5 mg
FormatA 1 mg/ml solution in methyl acetate
Molecular Weight316.4
Purity≥95%
Research AreaCyclooxygenase Pathway, Endocrinology & Metabolism, Hormones & Receptors, Lipid Biochemistry, Metabolic Diseases, PPARs
Storage-20
FormulaC20H28O3
OriginUSA

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) Epigenetic silencing of interleukin-10 by host-derived oxidized phospholipids supports a lethal inflammatory response to infectionsImmunitySeptember 9, 2025Marco Di Gioia, Valentina Poli, Piao J. Tan, Roberto Spreafico, Anne Chu, Alex G. Cuenca, Zhongyang Wu, Mehdi Benamar, Laura Pandolfi, Federica Meloni, et al.870606 LysoPC,Avanti Polar Lipids,Cat# 830071 KOdiAPC,Cayman Chemicals,Cat# 62945 15d-PGJ2,Cayman Chemicals,Cat# 18570 2-deoxy-D-Glucose (2-DG),Cayman Chemicals,Cat# 14325 "Escherichia coli LPS (Serotype O555:B5, TLRgrade)",Enzo Life Sciences

(2) Fatty acid binding proteins are novel modulators of synaptic epoxyeicosatrienoic acid signaling in the brainScientific ReportsSeptember 14, 2023Sherrye T. Glaser, Kalani Jayanetti, Saida Oubraim, Andrew Hillowe, Elena Frank, Jason Jong, Liqun Wang, Hehe Wang, Iwao Ojima, Samir Haj-Dahmane, et al.14,15-EET (#50651), PGE2-GE (#10140), PGE2 (#14010), PGF2α (#16010), PGF2α-EA (#16013), 15d-PGJ2 (#18570), LPA (#10010093), and 11-(dansylamino) undecanoic acid (DAUDA, #10005188) were from Cayman Chemical.

(3) Activation of GPR44 decreases severity of myeloid leukemia via specific targeting of leukemia initiating stem cellsCell reportsJuly 25, 2023Qian F, Nettleford SK, Zhou J, Arner BE, Hall MA, Sharma A, Annageldiyev C, Rossi RM, Tukaramrao DB, Sarkar D, et al."13,14-dihydro-15-keto Prostaglandin D2",Cayman Chemical Co.,Cat# 12610 "15-deoxy-Δ12,14-Prostaglandin J2",Cayman Chemical Co.,Cat# 18570 "15-deoxy-Δ12,14-PGJ2 ELISA kit",Enzo,Cat# ADI-900–023 2-Mercaptoethanol (BME),Sigma Aldrich,Cat#

(4) Biosynthesis of prostaglandin 15dPGJ2 -glutathione and -cysteine conjugates in macrophages and mast cells via MGST3: Biosynthesis of 15dPGJ2-conjugatesJournal of Lipid ResearchDecember 1, 2022Julia Steinmetz-Späh, Jianyang Liu, Rajkumar Singh, Maria Ekoff, Sanjaykumar Boddul, Xiao Tang, Filip Bergqvist, Helena Idborg, Pascal Heitel, Elin Rönnberg, et al.metabolites. Material and Methods Materials Prostaglandins including 15-deoxy-Δ12,14-PGJ2 (CAY-18570-1) and 15-deoxy-Δ12,14-PGJ2-GS (CAY-18580-100) were purchased from Cayman Chemicals Co. (Ann Arbor MI).

(5) 15d-PGJ(2) Promotes ROS-Dependent Activation of MAPK-Induced Early Apoptosis in Osteosarcoma Cell In Vitro and in an Ex Ovo CAM AssayInternational journal of molecular sciencesOctober 29, 2021Mikulčić M, Tabrizi-Wizsy NG, Bernhart EM, Asslaber M, Trummer C, Windischhofer W, Sattler W, Malle E, Hrzenjak A.this field. 4. Materials and Methods 4.1. Materials 15d-PGJ2 (15-deoxy-Δ12,14-prostaglandin J2, #18570, Cayman Chemical Company, Ann Arbor, MI, USA) was dissolved under sterile conditions in dimethyl sulfoxide (DMSO

(6) Oxylipin biosynthesis reinforces cellular senescence and allows detection of senolysisCell metabolismJune 1, 2021Wiley CD, Sharma R, Davis SS, Lopez-Dominguez JA, Mitchell KP, Wiley S, Alimirah F, Kim DE, Payne T, Rosko A, et al.,Cayman Chemical Company,16010 Prostaglandin J2,Cayman Chemical Company,18500 "15-deoxy-Δ12,14-Prostaglandin J2",Cayman Chemical Company,18570 "1a,1b-dihomo-15-deoxy-Δ12,14-Prostaglandin J2",Jubilant Chemsys,P1171 "13,14-dihydro-15-keto Prostaglandin D2

(7) Mycolactone toxin induces an inflammatory response by targeting the IL-1β pathway: Mechanistic insight into Buruli ulcer pathophysiologyPLoS pathogensDecember 1, 2020Foulon M, Robbe-Saule M, Manry J, Esnault L, Boucaud Y, Alcaïs A, Malloci M, Fanton d'Andon M, Beauvais T, Labarriere N, et al.MCC950 (InvivoGen inh_mcc), an NLRP3 inhibitor; 15-deoxyΔ12,14-prostaglandin J2 (Cayman Chemicals ref. 18570), an NLRP3/1 inhibitor; N-acetyl-L-cysteine (NAC, Sigma A9165), a ROS inhibitor; and Z-VAD-FMK (InvivoGen

(8) PGE1 and PGA1 bind to Nurr1 and activate its transcriptional functionNature Chemical BiologyAugust 1, 2020Sreekanth Rajan et al.(no. 16950), PGE1 (no. 13010), PGE2 (no. 14010), PGE3 (no. 14990), PGA1 (no. 10010), 15d-PGJ2 (no. 18570), 9-cis-retinoic acid (no. 14587), 27-hydroxycholesterol (no. 14791), cortisol (no. 16063) and MPP+ iodide

(9) Positive Reinforcing Mechanisms between GPR120 and PPARγ Modulate Insulin SensitivityCell metabolismJune 2, 2020Paschoal VA, Walenta E, Talukdar S, Pessentheiner AR, Osborn O, Hah N, Chi TJ, Tye GL, Armando AM, Evans RM, et al.Dynabeads Protein A for immunoprecipitation,Thermo Fisher Scientific,Cat# 10001D 15d-PGJ2,Cayman Chemical,Cat# 18570-1 mg DHA,Cayman Chemical,Cat# 90310-500 mg TNFα,R&D Systems,Cat# 510-RT-050 CpdA,"Merck & Co., (Oh

(10) Mutant KRAS Enhances Tumor Cell Fitness by Upregulating Stress GranulesCellDecember 15, 2016Grabocka E, Bar-Sagi D.,Santa Cruz Biotechnology,Cat#sc-217785; CAS# 179324-69-7 "15-deoxy-Δ12,14-Prostaglandin J2(15-d-PGJ2)",Cayman,Cat#18570; CAS# 87893-55-8 Prostaglandin E2,Tocris Bioscience,Cat#2296; CAS# 363-24-6 Diclofenac sodium,Selleck,Cat#S1903;

(11) Electrophilic lipid mediator 15-deoxy-Δ12,14-prostaglandin j2 modifies glucocorticoid signaling via receptor SUMOylationMolecular and cellular biologySeptember 1, 2014Paakinaho V, Kaikkonen S, Levonen AL, Palvimo JJ.SUMO-2/3 (M114-3) was from MBL International Corporation (Woburn, MA). 15-Deoxy⌬12,14-prostaglandin J2 (18570) and its biotinylated form (10141) were from Cayman Chemicals (Ann Arbor, MI). Human tumor necrosis

(12) Methods for imaging and detecting modification of proteins by reactive lipid speciesFree Radical Biology and MedicineAugust 1, 2009Ashlee N. Higdon, Brian P. Dranka, Bradford G. Hill, Joo-Yeun Oh, Michelle S. Johnson, Aimee Landar, Victor M. Darley-UsmarInvitrogen, Product # D2390)15-deoxy-Δ12,14-prostaglandin J2 (15d-PGJ2; Cayman Chemical, Product # 18570)Ethanol, HPLC gradeAcetonitrile, HPLC gradeMethanol, HPLC gradeChloroform, HPLC grade, preserved with

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15-deoxy-Δ12,14-Prostaglandin J2 from Cayman Chemical

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Cayman Chemical

Citations (12)

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15-deoxy-Δ12,14-Prostaglandin J2 from Cayman Chemical

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