Prostaglandin E2 14010 from Cayman Chemical

Product Specs
ItemProstaglandin E2
CompanyCayman Chemical
Price $104.00Supplier Page View Company Product Page
Catalog Number14010
Size5 mg
Research AreaCyclooxygenase Pathway, Endocrinology & Metabolism, Immunology & Inflammation, Inflammatory Lipid Mediators, Lipid Biochemistry, Prostaglandins, Reproductive Biology
FormatA crystalline solid
Molecular Weight352.5
Purity≥98%
Storage-20
FormulaC20H32O5
OriginUSA
Source/Expression SystemSynthetic

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) Structural basis for prostaglandin and drug transport via SLCO2A1Nat CommunMarch 20, 2026Chitra Joshi, Justin C. Deme, Yoshinobu Nakamura, Wei-Tse Hsu, Jonathan D. Goult, Takafumi Kato, Joanne L. Parker, Philip C. Biggin, Susan M. Lea, Takeo Nakanishi, et al.the different compounds at final concentrations of 1.4 mM Prostaglandin E2 (Cayman Chemical Cat. No. 14010), 0.5 mM for Tolcapone (Sigma Cat. No. SML0150), Fentiazac (MedChemExpress Cat. No. HY-118752) and Losartan Potassium

(2) Disruption of primary ciliary prostaglandin E2 signaling by transforming growth factor-β1 impairs endometrial receptivityJ Biomed SciMarch 11, 2026Huan-Tzu Hou, Wan-Ning Li, Ting-Chien Lin, Chih-Wei Lin, Po-Hung Pan, Chih-Jhen Lee, Yi-Chen Chen, Po-Fan Chen, Chia-Yih Wang, Meng-Hsing Wu, et al.a mixture of 10 nM 17β-estradiol, 1 μM medroxyprogesterone acetate, and 1 μM PGE2 (Cayman Chemical, 14010) in DMEM/F12 to induce decidualization for 24 h or 4 days. Detailed treatment protocols are provided

(3) Liver metastases dampen IL18-driven γδ T cell activity and immunotherapy responsiveness in colorectal cancerCell Reports MedicineFebruary 17, 2026Allard W.J. van Renterghem, Miguel Parra-Martinez, Maartje Witsen, Karlijn Verkerk, Marit Steur, Laurien J. Zeverijn, Krijn K. Dijkstra, Leila Akkari, Emile E. VoestEGF,Peprotech,Cat#AF-100-15 A83-01,Tocris,Cat#2939 SB202190,Cayman Chemicals,Cat#10010399 Prostaglandin E2,Cayman Chemicals,Cat#14010-1 Y-27632,Sigma-Aldrich,Cat#Y-0503 Human recombinant FGF-7,Peprotech,Cat#100-19 Human recombinant

(4) Mast cell-specific CysLT2 receptor signaling inhibits cysteinyl leukotriene-dependent mast cell activation and type 2 allergic lung inflammationCell ReportsJanuary 27, 2026Jun Nagai, Madeline M. Hastings, Airi Nishida, Sreyashi Majumdar, Kendall Zaleski, Sofia A. Marshall, Junrui Lin, Mira A.S. Saliman, Yumi Tani, Yamato Murakami, et al.No./ID: 330503 "Glycogen,RNA grade",Thermo Fisher Scientific,R0551 Prostaglandin E2,Cayman Chemical,14010 N-methyl Leukotriene C4,Cayman Chemical,13390 Leukotriene C4,Cayman Chemical,20210 Leukotriene D4,Cayman Chemical

(5) Postpartum lipid dysregulation in African American women who experienced cardiometabolic complications of pregnancyiScienceDecember 19, 2025Kristal Maner-Smith, Chih-Yu Chen, Zhenxin Hou, Xueyun Liu Gulbin, Jun Ahn, Eric A. Ortlund, Anne L. Dunlop, Erin FerrantiDocosanoyl Ethanolamide,Cayman Chemical,#10005823 "9,10 DiHOME",Cayman Chemical,#53400 Prostaglandin E2,Cayman Chemical,#14010 20-HETE,Cayman Chemical,#10007269 9-HETE,Cayman Chemical,#34400 "14,15 DiHET",Cayman Chemical,#10007267 5 (S)HETE

(6) FABP3 Mediates Lipid Droplet Accumulation and Adhesive Capacity in Bovine Endometrial Epithelial Cells via PGE2/PTGER4/PPAR AxisAnimals (Basel)November 26, 2025Beibei Zhang, Yutong Yan, Ming Cheng, Tengfei Guo, Kangkang Gao, Aihua Wang, Pengfei Lin, Dong Zhou, Yaping Jinmimic the uterine hormone environment of dairy cows during the luteal phase. Then, PGE2 (10−8–10−6 M; 14010, Cayman, Ann Arbor, MI, USA) was added to the medium, and the cells were cultured for 24 h. For inhibitor

(7) Membrane disruption attenuates agonist potency in prostanoid receptorsBiochemical JournalOctober 17, 2025Uurtuya Hochban, Imke Wallenstein, Michaela Ulrich, Alwina Bittner, Lisa Spänig, Katharina Klingelhöfer, Sebastian Neumann, Torsten Steinmetzer, Moritz Bünemann, Michael Kurzconformation sensor [20], and the murine α2A-AR conformation sensor CAM [19]. In this study, we used PGE2 (14010), PGD2 (12010), U-46619 (16450), L-161,982 (10011565), Iloprost (18215), and 11-deoxy PGE2 (14520) (all

(8) Multimodal targeting of metastatic renal cell carcinoma via CD70-directed allogeneic CAR-NKT cellsCell Reports MedicineSeptember 16, 2025Yan-Ruide Li, Junhui Hu, Zhe Li, Enbo Zhu, Yuning Chen, Tyler Halladay, Xinyuan Shen, Ying Fang, Yichen Zhu, Zibai Lyu, et al.,BD Biosciences,CAT#554724 Poloxamer Synperonic F108,Millipore Sigma,CAT#07579-250G-F Prostaglandin E2 (PGE2),Cayman Chemical,CAT#14010 TrypLE™ Express Enzyme,ThermoFisher Scientific,CAT#12605010 Phorbol-12-myristate-13-acetate (PMA),Sigma,CAT#524400 "Ionomycin,

(9) Bidirectional Interaction Between PGE2-Preconditioned Mesenchymal Stem Cells and Myofibroblasts Mediates Anti-Fibrotic Effects: A Proteomic Investigation into Equine Endometrial Fibrosis ReversalProteomesSeptember 8, 2025Lidice Méndez-Pérez, Yat Sen Wong, Belén O. Ibáñez, Ioanna Martinez-Hormaza, Lleretny Rodríguez-Álvarez, Fidel Ovidio Castroconditioned with 3 μM PGE2 (high-glucose DMEM supplemented with 1× AAM and 3 μM PGE2 (Cayman Chemical 14010, Ann Harbor, MI, USA) and incubated for 24 h (72 h in Figure 1). 2.1.4. Co-Culture of Myofibroblasts

(10) Multiomic profiling reveals that prostaglandin E2 reverses aged muscle stem cell dysfunction, leading to increased regeneration and strengthCell Stem CellJuly 3, 2025Yu Xin Wang, Adelaida R. Palla, Andrew T.V. Ho, Daniel C. L. Robinson, Meenakshi Ravichandran, Glenn J. Markov, Thach Mai, Chris Still, Akshay Balsubramani, Surag Nair, et al.11088815001 Streptavidin Microbeads,Miltenyi Biotech,Catalog# 130–048-101 Prostaglandin E2,Cayman Chemicals,Catalog# 14010 "16,16-dimethyl Prostaglandin E2",Tocris,Catalog# 4027 ONO-AE3–208,Cayman Chemicals,Catalog# 14522 Tamoxifen,VWR,Catalog#

(11) Peptidoglycan derived from Lacticaseibacillus rhamnosus and Lactobacillus acidophilus suppress TLR2/1-mediated inflammation in bovine endometrial epithelial cellsFrontiers in ImmunologyJune 18, 2025Elham Waehama, Kenji Fukuda, Alireza Mansouri, Malinda Hulugalla, Ihshan Akthar, Mohamed Samy Yousef, Akio Miyamotoat 4°C, and kept at -80°C for PGE2 quantification. A commercially available PGE2-ELISA kit (Item no.14010, Cayman Chemical, Ann Arbor, MI, USA) was used to determine PGE2 concentrations in BEEC-conditioned

(12) A CD4+ T cell-intrinsic complement C5aR2-prostacyclin-IL-1R2 axis orchestrates Th1 cell contractionImmunityJune 10, 2025Jubayer Rahman, Jack A. Bibby, Parul Singh, Nicolas S. Merle, Erin E. West, Andrea Bohrer, Katrin Mayer-Barber, Chengyu Liu, Lauren R. Brinster, Behdad Afzali, et al.al.68,N/A "Human IL-2 protein, recombinant",Peprotech,Cat# 200-02 PGI2 (prostacyclin),Cayman Chemicals,Cat# 14010 PGI2-R agonist (epoprostenol),TOCRIS,Cat# 2989 PGI2-R antagonist,TOCRIS,Cat# 4268 PGE2 (prostaglandin E2

(13) Murine Osteoblast and Osteoclast Co-culture on Demineralized Bone Paper for Bone RemodelingBIO-PROTOCOLJune 5, 2025Seema Amin, Hyejin Yoon, Dong-Hee Choi, Yi-Hao Hsu, Jungwoo Lee(CAYMAN Chemical Company, catalog number: 71820) 17. Prostaglandin E2 (PGE2) (Cayman Chemical Company, catalog number: 14010) 18. 4% Paraformaldehyde (Thermo Fisher Scientific, catalog number: J19943.K2) 19. Alexa Fluor 488 phalloidin

(14) Persistent changes in the dorsal root ganglion nociceptor translatome governs hyperalgesic priming in mice: roles of GPR88 and MeteorinPainJune 1, 2025Ishwarya Sankaranarayanan, Moeno Kume, Ayaan Mohammed, Juliet M. Mwirigi, Nikhil Nageswar Inturi, Gordon Munro, Kenneth A. Petersen, Diana Tavares-Ferreira, Theodore J. Price(R&D Systems, 206-IL) at a dosage of 0.1 ng or 100 ng prostaglandin E2 (PGE2; Cayman Chemical, cat# 14010) dissolved in sterile saline for priming experiments. RTI-13951–33 hydrochloride (MedChem express),

(15) Exercise plasma improves traumatic brain injury outcomes in miceSci RepMay 23, 2025Peyman Sahbaie, Xiaoyou Shi, Tian-Zhi Guo, Wen-Wu Li, Karen-Amanda Irvine, QiLiang Chen, J. David Clark25% differences detectable with 80% power at alpha 0.05. Drugs Prostaglandin E2 [100ng/15µl] (PGE2, 14010, Cayman Chemicals, MI, USA) is a principal mediator of inflammation and pain hypersensitivity. Stock

(16) Functional characterization of eicosanoid signaling in Drosophila developmentPLoS GenetMay 9, 2025Daiki Fujinaga, Cebrina Nolan, Naoki Yamanakacontaining 200 µM of a prostaglandin or a prostanoid analog (Cayman Chemical, PGD2, #12010; PGE2, #14010; PGF2α, #16010; U-46619, #16450; iloprost, #18215). Luminescence was detected every 0.2 seconds from

(17) GRK2 activates TRAF2–NF-κB signalling to promote hyperproliferation of fibroblast-like synoviocytes in rheumatoid arthritisActa Pharmaceutica Sinica BApril 1, 2025Chenchen Han, Liping Jiang, Weikang Wang, Shujun Zuo, Jintao Gu, Luying Chen, Zhuo Chen, Jiajie Kuai, Xuezhi Yang, Liang Xu, et al.(MH7A) were sourced from Beijing Jinheng Shengshi Technology Co., Ltd. PGE2 (Cayman Chemical, cat. 14010), recombinant rat TNF-α (Novoprotein, cat. CR38, purity >95%), recombinant human TNF-α (Novoprotein,

(18) IgA2 ACPA Drives a Hyper-Inflammatory Phenotype in Macrophages via ATP Synthase and COX2Eur J ImmunolApril 1, 2025Luís Almeida, Alice Bacon, Mohan Ghorasaini, Alwin J. van der Ham, René E. M. Toes, Martin Giera, Bart Everts(Sigma‐Aldrich, E1905), 1 µM Entosplenetinib (SelleneckChem, S7523), 10 µM Prostaglandin E2 (Cayman, 14010). After 24 h of stimulation, the supernatant was collected and stored at −20°C, if for ELISA, or at

(19) Celecoxib prevents malignant progression of smoking-induced lung tumors via suppression of the COX-2/PGE2 signaling pathway in miceFrontiers in ImmunologyMarch 19, 2025Kaori Sakurai, Shotaro Chubachi, Jun Miyata, Junko Hamamoto, Tatsuro Naganuma, Takashi Shimada, Shiro Otake, Shingo Nakayama, Hidehiro Irie, Akihiro Tsutsumi, et al.concentrations of PGD2, PGE2, PGF2α, and 12- hydroxyheptadecatrienoic acid (HHTrE) (Cayman Chemical, 12010; 14010; 16010; 34590). 2. Cells were treated with EP receptor antagonists (50 nM of EP1 antagonist, 3 μM of

(20) Distinct cAMP regulation in scleroderma lung and skin myofibroblasts governs their dedifferentiation via p38α inhibitionbioRxivMarch 1, 2025Jared D. Baas, John Varga, Carol Feghali-Bostwick, Marc Peters-Golden, Sean M. FortierRo 20–1724 (100 μM); and the pan-PDE inhibitor IBMX (500 μM) were purchased from Cayman Chemicals (14010, 13740, 15966, 11129, 18272, 13347). The pan-p38 inhibitor SB203580 (20 μM) and p38α inhibitor VX-702

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Prostaglandin E2 from Cayman Chemical

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Cayman Chemical

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Prostaglandin E2 from Cayman Chemical

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