FGF-21 Protein 2539-FG-025 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemFGF-21 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $362.00Supplier Page View Company Product Page
Catalog Number2539-FG-025
SpeciesHuman
Molecule NameFGF-21
Size25 ug
NCBI Full Gene Namefibroblast growth factor 21
FormatLyophilized from a 0.2 µm filtered solution in MES, Na2SO4, EDTA and DTT with BSA as a carrier protein
Purity>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 24 kDa, reducing conditions
Theoretical: 20.2 kDa
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemE. coli-derived Recombinant Human FGF-21 Protein
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Sizes Available: 25 ug

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Pemafibrate ameliorates renal injury through induction of FGF21 and ketone body production in male micePhysiol RepJanuary 30, 2025Kunihiko Takahara, Noriyuki Ouchi, Tomonobu Takikawa, Yuta Ozaki, Lixin Fang, Hiroshi Kawanishi, Minako Tatsumi, Yoshimitsu Yura, Katsuhiro Kato, Mikito Takefuji, et al.factor (FGF)‐21 and human transforming growth factor (TGF)‐β1 proteins were purchased from R&D Systems (2539‐FG‐025 and 240‐B‐002, respectively). Plasma FGF21 levels were measured using an enzyme‐linked immunosorbent assay

(2) A New Approach to the Quantification of Fibroblast Growth Factor 23-An Array Surface Plasmon Resonance Imaging BiosensorInternational journal of molecular sciencesOctober 18, 2023Tokarzewicz A, Ołdak Ł, Młynarczyk G, Klekotka U, Gorodkiewicz E.

(3) Epigenetic Regulation of Hepatic Lipid Metabolism by DNA MethylationAdvanced science (Weinheim, Baden-Wurttemberg, Germany)July 1, 2023Wang S, Zha L, Cui X, Yeh YT, Liu R, Jing J, Shi H, Chen W, Hanover J, Yin J, et al.primary hepatocytes were then treated with FGF15 (20 nM; Cat. Ab206457; Boston, MA) or FGF21 (20 nM; Cat. 2539FG025, R&D Systems, Minneapolis, NM) for 4 h before harvested for RNA extraction. Total RNA Extraction and

(4) Soluble α-klotho and heparin modulate the pathologic cardiac actions of fibroblast growth factor 23 in chronic kidney diseaseKidney internationalAugust 1, 2022Yanucil C, Kentrup D, Campos I, Czaya B, Heitman K, Westbrook D, Osis G, Grabner A, Wende AR, Vallejo J, et al.

(5) FGF21-FGFR4 signaling in cardiac myocytes promotes concentric cardiac hypertrophy in mouse models of diabetesScientific reportsMay 5, 2022Yanucil C, Kentrup D, Li X, Grabner A, Schramm K, Martinez EC, Li J, Campos I, Czaya B, Heitman K, et al.

(6) A novel selective PPARα modulator, pemafibrate promotes ischemia-induced revascularization through the eNOS-dependent mechanismsPLOS ONEJune 25, 2020Hiroshi Kawanishi, Koji Ohashi, Hayato Ogawa, Naoya Otaka, Tomonobu Takikawa, Lixin Fang, Yuta Ozaki, Mikito Takefuji, Toyoaki Murohara, Noriyuki Ouchipurchased from Cayman Chemical (11697). Recombinant human FGF21 protein was purchased from R&D system (2539-FG025). Plasma FGF21 levels were measured by ELISA kit (R & D system)(MF2100) [15]. Plasma adiponectin levels

(7) Peripherally derived FGF21 promotes remyelination in the central nervous systemThe Journal of clinical investigationSeptember 1, 2017Kuroda M, Muramatsu R, Maedera N, Koyama Y, Hamaguchi M, Fujimura H, Yoshida M, Konishi M, Itoh N, Mochizuki H, et al.

(8) Fibroblast Activation Protein Cleaves and Inactivates Fibroblast Growth Factor 21The Journal of biological chemistryMarch 11, 2016Dunshee DR, Bainbridge TW, Kljavin NM, Zavala-Solorio J, Schroeder AC, Chan R, Corpuz R, Wong M, Zhou W, Deshmukh G, et al.

(9) Unliganded fibroblast growth factor receptor 1 forms density-independent dimersThe Journal of biological chemistryOctober 2, 2015Comps-Agrar L, Dunshee DR, Eaton DL, Sonoda J.

(10) Sustained Brown Fat Stimulation and Insulin Sensitization by a Humanized Bispecific Antibody Agonist for Fibroblast Growth Factor Receptor 1/βKlotho ComplexEBioMedicineJuly 1, 2015Kolumam G, Chen MZ, Tong R, Zavala-Solorio J, Kates L, van Bruggen N, Ross J, Wyatt SK, Gandham VD, Carano RA, et al.

(11) Circulating αKlotho influences phosphate handling by controlling FGF23 productionThe Journal of clinical investigationDecember 1, 2012Smith RC, O'Bryan LM, Farrow EG, Summers LJ, Clinkenbeard EL, Roberts JL, Cass TA, Saha J, Broderick C, Ma YL, et al.

(12) FGF19 regulates cell proliferation, glucose and bile acid metabolism via FGFR4-dependent and independent pathwaysPloS oneMarch 18, 2011Wu AL, Coulter S, Liddle C, Wong A, Eastham-Anderson J, French DM, Peterson AS, Sonoda J.

(13) Altered splicing of FGFR1 is associated with high tumor grade and stage and leads to increased sensitivity to FGF1 in bladder cancerThe American journal of pathologyNovember 1, 2010Tomlinson DC, Knowles MA.

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Recombinant Human FGF-21 Protein

FGF-21 Protein

FGF-21 Protein

FGF-21 Protein

FGF-21 Protein from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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FGF-21 Protein from R&D Systems, a Bio-Techne Brand

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