Metformin hydrochloride, AMPK activator ab120847 from Abcam

Product Specs
ItemMetformin hydrochloride, AMPK activator
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab120847
Size100 mg
Purity0.99
TypeActivator/Agonist
Molecule NameMetformin hydrochloride

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Evaluation of photoreceptor-directed fibroblasts derived from retinitis pigmentosa patients with defects in the EYS gene: a possible cost-effective cellular model for mechanism-oriented drugStem cell research & therapyApril 11, 2022Rai D, Iwanami M, Takahashi Y, Komuta Y, Aoi N, Umezawa A, Seko Y.(Selleck chemicals, Cat#S1039), 4-PBA (WAKO, Cat#168-06471), NAC (WAKO, Cat#015-05132), metformin (Abcam, Cat#ab120847)), vehicle or no addition for Pt#1 and containing vehicle or no addition for N#3. Rapamycin was used

(2) The antiviral effect of metformin on zika and dengue virus infectionScientific reportsApril 22, 2021Farfan-Morales CN, Cordero-Rivera CD, Osuna-Ramos JF, Monroy-Muñoz IE, De Jesús-González LA, Muñoz-Medina JE, Hurtado-Monzón AM, Reyes-Ruiz JM, Del Ángel RM.cells were used as control. Drugs MET and LOV were obtained from Abcam Biochemicals (catalogue number ab120847 and ab120614, respectively). MET was dissolved in water to prepare a stock solution at 100 mM. LOV was

(3) NEAT1 regulates microtubule stabilization via FZD3/GSK3β/P-tau pathway in SH-SY5Y cells and APP/PS1 miceAgingNovember 18, 2020Zhao Y, Wang Z, Mao Y, Li B, Zhu Y, Zhang S, Wang S, Jiang Y, Xu N, Xie Y, et al.(n=6).) 3) a case group (which received daily intragastric administration of 200mg/kg metformin (Abcam, #ab120847) for 6 weeks, AD mice (n=6).) For Immunostaining, Wild Type and AD mice were killed by decapitation

(4) Metformin Inhibits Tumor Metastasis through Suppressing Hsp90α Secretion in an AMPKα1-PKCγ Dependent MannerCellsJanuary 7, 2020Yuanchao Gong, Caihong Wang, Yi Jiang, Shaosen Zhang, Shi Feng, Yan Fu, Yongzhang Luo(Manassas, VA, USA) and maintained in DMEM supplemented with 10% FBS and 1% antibiotic. Metformin (ab120847), AICAR (ab120358) and Compound C (ab120843) were purchased from Abcam (Shanghai, China). Antibodies

(5) Human blood vessel organoids as a model of diabetic vasculopathyNatureJanuary 1, 2019Wimmer RA, Leopoldi A, Aichinger M, Wick N, Hantusch B, Novatchkova M, Taubenschmid J, Hämmerle M, Esk C, Bagley JA, et al.absence of the following drugs: 2,4- Thiazolidinedione (5mM, Abcam ab144811), Metformin (5mM, Abcam ab120847), Acarbose (80μg/mL, Sigma A8980), Nateglindine (100μM, Sigma N3538), Diphenyleneiodonium (10μM), Glimepiride

(6) LKB1-AMPK modulates nutrient-induced changes in the mode of division of intestinal epithelial crypt cells in miceExperimental Biology and MedicineSeptember 1, 2017Katherine Blackmore, Weinan Zhou, Megan J DaileyCO2 for 4 h. Organoids were then supplied with 0 mM or 20 mM glucose and either 1 mM Metformin HCL (Ab120847, Abcam, San Francisco, CA), 1 mM Compound C (Ab120843, Abcam, San Francisco, CA) or a vehicle control

(7) DENV up-regulates the HMG-CoA reductase activity through the impairment of AMPK phosphorylation: A potential antiviral targetPLoS pathogensApril 1, 2017Soto-Acosta R, Bautista-Carbajal P, Cervantes-Salazar M, Angel-Ambrocio AH, Del Angel RM.control. AMPK activators Metformin and A769662 were obtained from Abcam Biochemicals (catalog number ab120847 and ab120335 respectively), TMPA (492910) and Compound C (171261) from EMD Millipore, lovastatin from Sigma

(8) Metformin Inhibits Advanced Glycation End Products-Induced Inflammatory Response in Murine Macrophages Partly through AMPK Activation and RAGE/NFκB Pathway SuppressionJournal of diabetes researchJanuary 1, 2016Zhou Z, Tang Y, Jin X, Chen C, Lu Y, Liu L, Shen C.medium to the final concentration of 20 μg/mL. Metformin hydrochloride (Abcam, Cambridge, UK, Cat# ab120847) was dissolved in water at a concentration of 50 mM and further diluted with culture medium to the final

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Metformin hydrochloride, AMPK activator from Abcam

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Metformin hydrochloride, AMPK activator from Abcam

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