Recombinant Mouse IL-34 (carrier-free) 577608 from BioLegend

Product Specs
ItemRecombinant Mouse IL-34 (carrier-free)
CompanyBioLegend
Price $3,046.00Supplier Page View Company Product Page
Catalog Number577608
Size500 µg
ApplicationsBioassay
Gene Nameinterleukin 34
Format0.22 µm filtered protein solution is in 10 mM Sodium Phosphate buffer, 500 mM NaCl, pH 7.4
Molecule NameIL-34
SpeciesMouse
NCBI Full Gene Namecentrosomal protein 104
Concentration10 and 25 µg sizes are bottled at 100 µg/mL. 100 µg size and larger sizes are lot-specific and bottled at the concentration indicated on the vial. To obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool

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BioLegend

8999 BioLegend Way

San Diego, California 92121

United States

Phone: 1-877-246-5343 Toll-Free, USA & Canada
1-858-768-5800 International
Fax: 1-877-455-9587

Company Profile

Website: biolegend.com

(1) Serotonin 2A receptor attenuates psoriatic inflammation by suppressing IL-23 secretion in monocyte-derived Langerhans cellsNature CommunicationsSeptember 29, 2025Yeh Fong Tan, Chen-Yun Yeh, Sheng-Yun Hsu, Chun-Hao Lu, Ching-Hui Tsai, Pei-Chuan Chiang, Hao-Jui Weng, Tsen-Fang Tsai, Yungling Leo LeeGM-CSF (PeproTech, 315-03), 5 ng/ml of TGF-β (BioLegend, 763104), and 8 ng/ml of IL-34 (BioLegend, 577604), plated on a 6 well plate, and incubated for 8 days at 37 °C. The medium was changed every 48 h. Monocyte-derived

(2) Response of spatially defined microglia states with distinct chromatin accessibility in a mouse model of Alzheimer's diseaseNature neuroscienceAugust 1, 2025Ardura-Fabregat A, Bosch LFP, Wogram E, Mossad O, Sankowski R, Aktories P, Kieger L, Cook J, Hasavci D, Ulupinar H, et al.with 40 μg kg−1 recombinant murine Csf1 (PeproTech, 315-02) in PBS and 100 μg kg−1 IL-34 (BioLegend, 577602) in PBS or PBS alone for 8 weeks. For scRNA-seq analysis of Csf1-treated mice, all animals were treated

(3) Gene expression of psychiatric disorder-related kinesin superfamily proteins (Kifs) is potentiated in alternatively activated primary cultured microgliaBMC Res NotesJanuary 30, 2025Suguru Iwata, Mitsuhiro Hyugaji, Yohei Soga, Momo Morikawa, Tetsuya Sasaki, Yosuke Takei2 ng/mL human transforming growth factor-β2 (TGF-β2, #100-35B, Peprotech), 100 ng/mL murine IL-34 (#577602, BioLegend), and 1.5 µg/mL ovine wool cholesterol (#700000P, Avanti Polar Lipids). Twenty-four hours

(4) A primary rat neuron-astrocyte-microglia tri-culture model for studying mechanisms of neurotoxicityFront ToxicolJanuary 10, 2025Jessie R. Badley, Aishwarya Bhusal, Pamela J. Leinderived) (PeproTech, 100-21).• Recombinant Mouse IL-34 Protein (R&D Systems, 5195-ML-010; or BioLegend, 577604)• Triton X-100 (Fisher, 9002-93-1). 2.3 Preparation of cell culture media, substrates, and other solutions 2.3.1

(5) Protocol for long-term monocultures of murine macrophages derived from distinct adult tissuesSTAR ProtocolsSeptember 20, 2024Philippe Petry, Philipp Aktories, Alexander Oschwald, Katrin KierdorfCSF-1,PeproTech,Cat# 315-02 Recombinant murine GM-CSF,PeproTech,Cat# 315-03 Recombinant murine IL-34,BioLegend,Cat# 577606 Sodium bicarbonate (NaHCO3),Roth,Cat# 6885.1 ,, Experimental models: Organisms/strains,Experimental models

(6) A human Tau expressing zebrafish model of progressive supranuclear palsy identifies Brd4 as a regulator of microglial synaptic eliminationNature communicationsSeptember 18, 2024Bai Q, Shao E, Ma D, Jiao B, Scheetz SD, Hartnett-Scott KA, Ilin VA, Aizenman E, Kofler J, Burton EA.

(7) Interleukin-34 cancels anti-tumor immunity by PARP inhibitorJournal of gynecologic oncologyMay 1, 2023Nakamura T, Kajihara N, Hama N, Kobayashi T, Otsuka R, Han N, Wada H, Hasegawa Y, Suzuki N, Seino KI.(DC medium). Cells were seeded at 8×106 cells per well in 4 mL of DC medium with ‘IL-34 100 ng/mL (#577608; BioLegend) or nothing’ and ‘niraparib 2.5 μM or dimethyl sulfoxide (DMSO)’ in 6-well plate and cultured

(8) An improved organotypic cell culture system to study tissue-resident macrophages ex vivoCell Rep MethodsAugust 22, 2022Aktories P, Petry P, Glatz P, Andrieux G, Oschwald A, Botterer H, Gorka O, Erny D, Boerries M, Henneke P, et al.Scientific,Cat#10270106 Recombinant Murine CSF-1,Peprotech,Cat# 315-02 Recombinant Murine IL-34,BioLegend,Cat# 577606 Recombinant Murine GM-CSF,Peprotech,Cat# 315-03 Percoll,Sigma-Aldrich,Cat# P4937 Poly I:C,Tocris,Cat#

(9) A primary rodent triculture model to investigate the role of glia-neuron crosstalk in regulation of neuronal activityFrontiers in aging neuroscienceJanuary 1, 2022Phadke L, Lau DHW, Aghaizu ND, Ibarra S, Navarron CM, Granat L, Magno L, Whiting P, Jolly S.growth factor-beta 2 (TGF-β2) (100-35B, Peprotech, Cranbury, USA), 100 ng/ml interleukin-34 (IL-34) (577606, BioLegend, San Diego, USA), 1.5 μg/ml cholesterol (700000P, Sigma-Aldrich, St. Louis, USA), and 1 μg/ml

(10) Microglia Require CD4 T Cells to Complete the Fetal-to-Adult TransitionCellAugust 6, 2020Pasciuto E, Burton OT, Roca CP, Lagou V, Rajan WD, Theys T, Mancuso R, Tito RY, Kouser L, Callaerts-Vegh Z, et al.

(11) Effects of IL-34 on Macrophage Immunological Profile in Response to Alzheimer's-Related Aβ₄₂ AssembliesFrontiers in immunologyJanuary 1, 2020Zuroff LR, Torbati T, Hart NJ, Fuchs DT, Sheyn J, Rentsendorj A, Koronyo Y, Hayden EY, Teplow DB, Black KL, et al.ng/mL M-CSF (PeproTech #315-02; 100 µg/ml) and/or 20 ng/mL IL34 (R&D Systems; #5195-ML; Biolegend #577602; 100 µg/ml), Frontiers in Immunology | www.frontiersin.org 3 July 2020 | Volume 11 | Article 1449 Zuroff

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Recombinant Mouse IL-34 (carrier-free) from BioLegend

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Recombinant Mouse IL-34 (carrier-free) from BioLegend

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