Recombinant Human IL-3 (carrier-free) 578004 from BioLegend

Product Specs
ItemRecombinant Human IL-3 (carrier-free)
CompanyBioLegend
Price $347.00Supplier Page View Company Product Page
Catalog Number578004
Size25 µg
ApplicationsBioassay
Gene Nameinterleukin 3 (colony-stimulating factor, multiple)
NCBI Gene AliasesIL-3, MCGF, MULTI-CSF
NCBI Full Gene Nameinterleukin 3
Format0.22 µm filtered protein solution is in 20 mM Sodium Phosphate buffer, 300 mM NaCl, pH 6.0
Molecule NameIL-3
Concentration10 and 25 µg sizes are bottled at 200 µg/mL. 100 µg size and larger sizes are lot-specific and bottled at the concentration indicated on the vial. To obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool
SpeciesHuman

Add to Compare List

BioLegend

8999 BioLegend Way

San Diego, California 92121

United States

Phone: 1-877-246-5343 Toll-Free, USA & Canada
1-858-768-5800 International
Fax: 1-877-455-9587

Company Profile

Website: biolegend.com

(1) Microglial MARCO facilitates Varicella zoster virus uptake and triggers TLR2-mediated neuroinflammationJ Biomed SciMay 23, 2026Ji-Soo Lim, Soo-Jin Oh, Ji-Yeun Hur, Subin Oh, Seuk-Min Ryu, Rafael T. Han, Hosun Park, Dawn M. E. Bowdish, Ok Sarah Shin2-mercaptoethanol (21985-023, Gibco), 50 ng/mL SCF, 50 ng/mL M-CSF (574804, BioLegend), 50 ng/mL IL3 (578004, BioLegend), 50 ng/mL FLT3 (GMP-10315-HNAE1-L-AF, Sino Biological), and 5 ng/mL TPO (763702, BioLegend).

(2) Impact of dipeptidyl peptidase I and neutrophil serine proteases on neutrophil functional responsesFrontiers in PharmacologyApril 24, 2026Dedong Li, Kuan-Ju Chen, Nandita Niranjan, Jessica Basso, Daniel LaSala, Mei-Fong Pang, Craig Smith, Tam Nguyen, Vanessa de Carvalho Oliveira, David C. Cipolla, et al.medium supplemented with 100 ng/mL rh-SCF (BioLegend, Cat# 573906), 100 ng/mL rh-IL-3 (BioLegend, Cat# 578006), and 10 ng/mL rh-G-CSF (BioLegend, Cat# 578606). Treatment groups received vehicle or brensocatib at

(3) Targeted Inhibition of ELANE Expression Using Adenine Base Editing to Treat Severe Congenital NeutropeniaMolecular Therapy Methods & Clinical DevelopmentDecember 11, 2025Betül Findik, Benjamin Dannenmann, Franka Bernhard, Masako Monika Kaufmann, Sandra Ammann, Sergey Kandabarau, Maksim Klimiankou, Fabian Mauch, Patrick Münzer, Oliver Borst, et al.supplemented with 1% penicillin/streptomycin, 1% glutamine, and cytokines: 20 ng/mL IL-3 (BioLegend, #578006), 20 ng/mL IL-6 (R&D Systems, #7270-IL-100/CF), 20 ng/mL TPO (BioLegend, #763706), 50 ng/mL SCF (R&D

(4) The Parkinson's disease-associated LRRK2-G2019S variant restricts serine metabolism, leading to microglial inflammation and dopaminergic neuron degenerationJ NeuroinflammationOctober 27, 2025Henry Kurniawan, Sarah L. Nickels, Alise Zagare, Elisa Zuccoli, Isabel Rosety, Gemma Gomez-Giro, Enrico Glaab, Jens C. Schwamborn100 ng/ml macrophage colony-stimulating factor M-CSF, Biolegend 574808 and 25 ng/ml IL-3, Biolegend 578008) to generate macrophage precursors. Microglia differentiation Macrophage precursors were harvested

(5) WNK1 signalling regulates amino acid transport and mTORC1 activity to sustain acute myeloid leukaemia growthNat CommunMay 27, 2025Shunlei Duan, Karl Agger, Jan-Erik Messling, Koutarou Nishimura, Xuerui Han, Isabel Peña-Rømer, Pavel Shliaha, Helene Damhofer, Max Douglas, Manas Kohli, et al.mL in Myelocult H5100 medium (Stem Cell Technologies, #05150), supplemented with 20 ng/mL of IL-3 (#578004, BioLegend), G-CSF (#578604, BioLegend), and TPO (#763704, BioLegend). The cells were cultured either

(6) Pharmacological targeting of mitophagy via ALT001 improves herpes simplex virus 1 (HSV1)-mediated microglial inflammation and promotes amyloid β phagocytosis by restricting HSV1 infectionTheranosticsMarch 31, 2025Soo-Jin Oh, Young Yeon Kim, Ruiying Ma, Seok Tae Choi, Se Myeong Choi, Jong Hyun Cho, Ji-Yeun Hur, Yongjin Yoo, Kihoon Han, Hosun Park, et al.2-Mercaptoethanol (21985-023, Gibco), 50 ng/ml SCF, 50 ng/ml M-CSF (574804, BioLegend), 50 ng/ml IL-3 (578004, BioLegend), 50 ng/ml FLT3 (GMP-10315-HNAE1-L-AF, Sino Biological), and 5 ng/ml TPO (763702, BioLegend).

(7) Metabolic reprogramming regulated by TRAF6 contributes to the leukemia progressionLeukemiaMay 1, 2024Shinichiro Matsui, Chihiro Ri, Lyndsey C. Bolanos, Kwangmin Choi, Asuka Shibamiya, Arata Ishii, Koji Takaishi, Nagisa Oshima-Hasegawa, Shokichi Tsukamoto, Yusuke Takeda, et al.with 10% fetal bovine serum (FBS) and 1% penicillin and streptomycin (P/S). 10 ng/mL of human IL-3 (578006. Biolegend) was added to the medium for culturing TF-1. HEK 293 T cells was purchased from ATCC, and

(8) Pharmacological inhibition of BACE1 suppresses glioblastoma growth by stimulating macrophage phagocytosis of tumor cellsNature cancerNovember 1, 2021Zhai K, Huang Z, Huang Q, Tao W, Fang X, Zhang A, Li X, Stark GR, Hamilton TA, Bao S.

(9) Tau Pathology Drives Dementia Risk-Associated Gene Networks toward Chronic Inflammatory States and ImmunosuppressionCell reportsNovember 17, 2020Rexach JE, Polioudakis D, Yin A, Swarup V, Chang TS, Nguyen T, Sarkar A, Chen L, Huang J, Lin LC, et al.beta-mercaptoethanol (Life Technologies, 31350–010), 100ng/mL M-CSF (Biolegend, 574806), 25ng/mL IL-3 (Biolegend, 578006), and 2mM GlutaMAX (Thermo Fisher, 35050–061). EBs seeded in T-75 flasks were cultured at 37°C and 5%

(10) "Macrophages Derived From Human Induced Pluripotent Stem Cells Are Low-Activated ""Naïve-Like"" Cells Capable of Restricting Mycobacteria Growth"Frontiers in immunologyJanuary 1, 2020Nenasheva T, Gerasimova T, Serdyuk Y, Grigor'eva E, Kosmiadi G, Nikolaev A, Dashinimaev E, Lyadova I.βmercaptoethanol (iMC/iMφ differentiation medium) in the presence of 25 ng/ml IL-3 and 100 ng/ml CSF1 (cat #578006 and #574804, both from Biolegend). Full medium change was performed every 7 days. When floating monocyte-like

(11) Human mast cells promote colon cancer growth via bidirectional crosstalk: studies in 2D and 3D coculture modelsOncoimmunologyJanuary 1, 2018Yu Y, Blokhuis B, Derks Y, Kumari S, Garssen J, Redegeld F.with human LDL (50 μg/ml) (StemCell, 02698). On day 1, human recombinant IL-3 (100ng/ml) (Biolegend, 578006) and SCF (100ng/ml) (Miltenyi, 130–096-695) were added. Every three to four days, IL-3 and SCF were

Be the First to Write a Review!

Recombinant Human IL-3 (carrier-free) from BioLegend

Description

BioLegend

Citations (11)

Reviews

Recombinant Human IL-3 (carrier-free) from BioLegend

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map