Human Collagen Type IV 009-001-106 from Rockland Immunochemicals, Inc.

Supplier Images

ELISA results using Human Collagen Type IV

NORAD reverses the inhibitory effects of miR-485 on HG-induced HMCs. (F) Contents of Col. IV, FN and PAI-1 in HG-induced HMCs measured via ELISA **P<0.01 vs. miR-NC; #P<0.05 vs. miR-485 mimics. miR, microRNA; NORAD, non-coding RNA activated by DNA damage; HG, high glucose; HMCs, human mesangial cells; ov, overexpression vector; NC, negative control; Col. IV, type IV collagen; FN, fibronectin; PAI-1, plasminogen activator inhibitor 1. Figure 4. PMID: 34194552.
Human Collagen Type IV

SDS-PAGE Results of Human Collagen Type IV. Lane 1: Human Collagen Type IV Reduced (5.0µg). Lane 2: Opal Prestained Molecular Weight Protein (p/n MB-210-0500). Lane 3: Human Collagen Type IV Non-Reduced (5.0µg). 4-20% Gel, Coomassie Stained. Observed MW: Type IV a1, a2, a3 bands.
ELISA results using Human Collagen Type IV

Knockdown of NORAD inhibits proliferation, inflammation and fibrosis in HG-induced HMCs. Levels of (G) Col. IV in HMCs measured via ELISA. **P<0.01 vs. NG; ##P<0.01 vs. HG + si-NC. NORAD, non-coding RNA activated by DNA damage; NG, normal glucose; HG, high glucose; HMCs, human mesangial cells; si, small interfering RNA; NC, negative control Col. IV, type IV collagen. Figure 2. PMID: 34194552.
SDS-PAGE Results of Human Collagen Type IV

SDS-PAGE Results of Human Collagen Type IV. Lane 1: Human Collagen Type IV Reduced (5.0µg). Lane 2: Opal Prestained Molecular Weight Protein (p/n MB-210-0500). Lane 3: Human Collagen Type IV Non-Reduced (5.0µg). 4-20% Gel, Coomassie Stained. Observed MW: Type IV α1, α2, α3 bands.
ELISA results using Human Collagen Type IV

NORAD knockdown inhibits proliferation, inflammation and fibrosis in HG-induced HMCs by regulating the miR-485/NRF1 axis. (G) Contents of Col. IV, FN and PAI-1 in HG-induced HMCs as determined via ELISA. **P<0.01 vs. si-NC; #P<0.05 vs. si-NORAD + inhibitor NC; &P<0.05 vs. si-NORAD + ov-NC. miR, microRNA; NORAD, non-coding RNA activated by DNA damage; NRF1, nuclear respiratory factor 1; HG, high glucose; HMCs, human mesangial cells; ov, overexpression vector; si, small interfering RNA; NC, negative control; Col. IV, type IV collagen; FN, fibronectin; PAI-1, plasminogen activator inhibitor 1. Figure 6. PMID: 34194552.

Be the first to write a review!

Citations:

(1)

Supplier Page

Supplier Page from
Rockland Immunochemicals, Inc. for
Human Collagen Type IV

Request Info

Description

Collagen type IV is a type of collagen found primarily in the basal lamina. The type IV collagen C4 domain at the C-terminus is not removed in post-translational processing, and the fibers link head-to-head, rather than in parallel. Also, collagen type IV lacks the regular glycine in every third residue necessary for the tight, collagen helix. This makes the overall arrangement more sloppy with kinks. These two features cause collagen IV to form in a sheet, the form of the basal lamina. There are six human genes associated with collagen IV: COL4A1, COL4A2, COL4A3, COL4A4, COL4A5 and COL4A6

ELISA results using Human Collagen Type IV