Ubiquitin Aldehyde sc-4316 from Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

(1) MDM2-mediated degradation of WRN promotes cellular senescence in a p53-independent mannerOncogeneApril 1, 2019Liu B, Yi J, Yang X, Liu L, Lou X, Zhang Z, Qi H, Wang Z, Zou J, Zhu WG, et al.

(2) mTORC1-Regulated and HUWE1-Mediated WIPI2 Degradation Controls Autophagy FluxMolecular cellOctober 18, 2018Wan W, You Z, Zhou L, Xu Y, Peng C, Zhou T, Yi C, Shi Y, Liu W.

(3) Distinct kinetics of serine and threonine dephosphorylation are essential for mitosisNature cell biologyDecember 1, 2017Hein JB, Hertz EPT, Garvanska DH, Kruse T, Nilsson J.

(4) Interaction between von Hippel-Lindau Protein and Fatty Acid Synthase Modulates Hypoxia Target Gene ExpressionScientific reportsAugust 3, 2017Sun W, Kato H, Kitajima S, Lee KL, Gradin K, Okamoto T, Poellinger L.30 min at 37 °C in the absence or presence of 2.5 μg ubiquitin aldehyde (Santa Cruz Biotechnology, sc-4316) in a 30 μl reaction. Knockdown by siRNA and expression by lentiviral vector siRNAs to human FASN

(5) Astragalus polysaccharide, a component of traditional Chinese medicine, inhibits muscle cell atrophy (cachexia) in an in vivo and in vitro rat model of chronic renal failure by activating the ubiquitin-proteasome pathwayExperimental and therapeutic medicineJuly 1, 2017Geng Z, Wei L, Zhang C, Yan X.antibodies against atrogin-1 (cat. no. ab74023, 1:10,000; Abcam, Cambridge, UK), ubiquitin (cat. no. sc-4316, 1:1,000) and NF-κB subunit p65 (cat. no. c-20, 1:2,000; both from Santa Cruz Biotechnology, Inc., Dallas,

(6) Fbxl12 triggers G1 arrest by mediating degradation of calmodulin kinase ICellular signallingOctober 1, 2013Mallampalli RK, Kaercher L, Snavely C, Pulijala R, Chen BB, Coon T, Zhao J, Agassandian M.

(7) Deficiency of cartilage oligomeric matrix protein causes dilated cardiomyopathyBasic research in cardiologySeptember 1, 2013Huang Y, Xia J, Zheng J, Geng B, Liu P, Yu F, Liu B, Zhang H, Xu M, Ye P, et al.

(8) Phosphorylation of AIB1 at mitosis is regulated by CDK1/CYCLIN BPloS oneJanuary 1, 2011Ferrero M, Ferragud J, Orlando L, Valero L, Sánchez del Pino M, Farràs R, Font de Mora J.

(9) The Epstein-Barr virus (EBV) deubiquitinating enzyme BPLF1 reduces EBV ribonucleotide reductase activityJournal of virologyMay 1, 2009Whitehurst CB, Ning S, Bentz GL, Dufour F, Gershburg E, Shackelford J, Langelier Y, Pagano JS.

(10) Structure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14The EMBO journalNovember 2, 2005Hu M, Li P, Song L, Jeffrey PD, Chenova TA, Wilkinson KD, Cohen RE, Shi Y.

(11) Epstein-Barr virus activates beta-catenin in type III latently infected B lymphocyte lines: association with deubiquitinating enzymesProceedings of the National Academy of Sciences of the United States of AmericaDecember 23, 2003Shackelford J, Maier C, Pagano JS.

(13) A novel active site-directed probe specific for deubiquitylating enzymes reveals proteasome association of USP14The EMBO journalSeptember 17, 2001Borodovsky A, Kessler BM, Casagrande R, Overkleeft HS, Wilkinson KD, Ploegh HL.

(14) Structural basis for the specificity of ubiquitin C-terminal hydrolasesThe EMBO journalJuly 15, 1999Johnston SC, Riddle SM, Cohen RE, Hill CP.

(17) Kinetic studies on the inhibition of isopeptidase T by ubiquitin aldehydeBiochemistryOctober 1, 1996Melandri F, Grenier L, Plamondon L, Huskey WP, Stein RL.

(18) Recognition of modified forms of ribonuclease A by the ubiquitin systemThe Journal of biological chemistryOctober 5, 1989Dunten RL, Cohen RE.

(19) Ubiquitin-aldehyde: a general inhibitor of ubiquitin-recycling processesProceedings of the National Academy of Sciences of the United States of AmericaApril 1, 1987Hershko A, Rose IA.

Ubiquitin Aldehyde