Description
An antioxidant with neuroprotective properties; reduces cell death induced by hydrogen peroxide, paraquat, S-nitrocysteine, SIN-1, or BSO in rat striatal cultures from 0.1-10 µM; cytosolic microinjection prevents glutamate-induced cell death and phosphorylation of 12-LO in HT4 neurons; reduces glutamate-induced cytosolic and mitochondrial production of ROS, accumulation of ΔN-Bcl-xL, and cell death in primary rat hippocampal neurons; reduces infarct size in a spontaneously hypertensive rat model of stroke induced by tandem right common carotid artery and middle cerebral artery occlusion at 50 mg/kg