Recombinant Human KIR2DL2/CD158b1 Fc Chimera Protein, CF 3015-KR-050 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human KIR2DL2/CD158b1 Fc Chimera Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $544.00Supplier Page View Company Product Page
Catalog Number3015-KR-050
Size50 ug
ApplicationsBioactivity
FormatLyophilized from a 0.2 µm filtered solution in PBS
Molecular WeightObserved: 65-75 kDa, reducing conditions
Theoretical: 51.2 kDa (monomer)
Conjugate/TagUnconjugated
Purity>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecule NameKIR2DL2/CD158b1
SpeciesHuman
Source/Expression SystemNS0-derived Recombinant Human KIR2DL2/CD158b1 Fc Chimera Protein, CF
NCBI Full Gene Namekiller cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2
NCBI Gene AliasesCD158B1, CD158b, NKAT6, p58.2, NKAT-6
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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United States

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(1) Preclinical characterization of MTX-101: a novel bispecific CD8 Treg modulator that restores CD8 Treg functions to suppress pathogenic T cells in autoimmune diseasesFrontiers in immunologyJanuary 1, 2024Gardell JL, Maurer ME, Childs MM, Pham MN, Meengs B, Julien SH, Tan C, Boster DR, Quach P, Therriault JH, et al.Co-binding experiments were performed by coupling KIR2DL2-Fc (R&D Systems, Minneapolis, MN, USA, cat# 3015-KR-050) and CD8α to separate AR2G (amine-reactive) sensor tips (Sartorius) via amine chemistry (EDC/NHS). MTX-101

(2) HLA-C-restricted viral epitopes are associated with an escape mechanism from KIR2DL2⁺ NK cells in Lassa virus infectionEBioMedicineFebruary 1, 2019Wauquier N, Petitdemange C, Tarantino N, Maucourant C, Coomber M, Lungay V, Bangura J, Debré P, Vieillard V.

(3) Peptide selectivity discriminates NK cells from KIR2DL2- and KIR2DL3-positive individualsEuropean journal of immunologyFebruary 1, 2015Cassidy S, Mukherjee S, Myint TM, Mbiribindi B, North H, Traherne J, Mulder A, Claas FH, Purbhoo MA, Das J, et al.

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6/5/2013Recombinant human KIR2DL2-Fc/CD-158b1 Chimera from R&D Systems Hugo HiltonThis highly purified recombinant protein binds specifically to HLA class I allotypes that recognize KIR2DL2 (HLA-C).

Recombinant Human KIR2DL2/CD158b1 Fc Chimera Protein, CF from R&D Systems, a Bio-Techne Brand