Recombinant Human Endoglin/CD105 Fc Chimera Protein, CF 6578-EN-025 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human Endoglin/CD105 Fc Chimera Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $454.00Supplier Page View Company Product Page
Catalog Number6578-EN-025
Size25 ug
ApplicationsBioactivity
FormatLyophilized from a 0.2 µm filtered solution in PBS
Purity>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 100-115 kDa, reducing conditions
Theoretical: 87.3 kDa (monomer)
Conjugate/TagUnconjugated
Source/Expression SystemCHO-derived Recombinant Human Endoglin/CD105 Fc Chimera Protein, CF
Molecule NameEndoglin/CD105
SpeciesHuman
NCBI Full Gene Nameendoglin
NCBI Gene AliasesHHT1, ORW1, END
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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(1) TGF-β contamination of purified recombinant GDF15PloS oneJanuary 1, 2017Olsen OE, Skjærvik A, Størdal BF, Sundan A, Holien T.

(2) Reduced endoglin activity limits cardiac fibrosis and improves survival in heart failureCirculationJune 5, 2012Kapur NK, Wilson S, Yunis AA, Qiao X, Mackey E, Paruchuri V, Baker C, Aronovitz MJ, Karumanchi SA, Letarte M, et al.

(3) Soluble endoglin specifically binds bone morphogenetic proteins 9 and 10 via its orphan domain, inhibits blood vessel formation, and suppresses tumor growthThe Journal of biological chemistryAugust 26, 2011Castonguay R, Werner ED, Matthews RG, Presman E, Mulivor AW, Solban N, Sako D, Pearsall RS, Underwood KW, Seehra J, et al.

Recombinant Human Endoglin/CD105 Fc Chimera Protein, CF from R&D Systems, a Bio-Techne Brand