Description
An estradiol metabolite produced during pregnancy; total plasma estriol levels increased from 10 weeks gestation to approximately 150 ng/ml at week 38 in healthy pregnant women; originates from fetal DHEAS and serves as a direct marker of fetal adrenal gland activity; saliva contains primarily unbound and unconjugated estriol and is commonly used for monitoring estriol levels; plasma levels of estriol in males and non-pregnant females is less than 2 ng/ml