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Protein Biochemistry
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(±)-C75
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(±)-C75
(±)-C75
(±)-C75 from Cayman Chemical
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Citations:
(8)
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Cayman Chemical for
(±)-C75
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Description
An anorexigenic inhibitor of FASN; leads to profound weight loss and feeding inhibition in both high-fat diet wild type obese and leptin-deficient ob/ob mice; cytotoxic to many human cancer cell lines
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
(±)-C75
Company
Cayman Chemical
Price
$152.00
Supplier Page
View Company Product Page
Catalog Number
10005270
Quantity
5 mg
Research Area
Cancer, Cofactors & Vitamins, Endocrinology & Metabolism, Fatty Acids, Lipid Biochemistry, Metabolic Diseases, Metabolism, Obesity, Synthesis
Format
A crystalline solid
Molecular Weight
254.3
Purity
≥98%
Storage
-20
Formula
C14H22O4
Origin
USA
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Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (8)
(1)
Diverse biophysical and molecular mechanisms drive phytoplankton sinking in response to starvation
PLOS Biology
November 19, 2025
Yanqi Wu, Vieyiti K. Kouadio, Thomas R. Usherwood, Justin Li, Margaret Bisher, Reshum Aurora, Aaron Z. Lam, Alice R. Lam, Abigail K. R. Lytton-Jean, Scott R. Manalis,
et al.
synthesis was inhibited with cerulenin (
Cayman Chemical
, Cat#
10005647
) and
C75
(
Cayman Chemical
, Cat#
10005270
). Lipid synthesis
inhibitors
were used at 10 µM concentration and the
treatment duration
corresponded
(2)
Plasma membrane accessible cholesterol is regulated by ACC1 and lipid droplets
bioRxiv
August 31, 2025
Kalani M. Wijesinghe, Chai-wan Kim, Emily O. Schad, Shuo Li, Summer Chen, Erin Takeshima, Chandni B. Khandwala, Desiree Tillo, Andres M. Lebensohn, James A. Olzmann,
et al.
Cayman Chemical
), the ACAT1/2
inhibitor
SZ58–035 (50 μM) (
S9318
,
Millipore Sigma
), the FASN
inhibitor
C75
(10 μM) (
10005270
,
Cayman Chemical
), the AMPK
inhibitor
Dorsomorphin dihydrochloride
(2.5 μM) (
HY-13418
,
MedChemExpress
),
(3)
A Planar Culture Model of Human Absorptive Enterocytes Reveals Metformin Increases Fatty Acid Oxidation and Export
Cellular and Molecular Gastroenterology and Hepatology
April 28, 2022
Ismael Gomez-Martinez, R. Jarrett Bliton, Keith A. Breau, Michael J. Czerwinski, Ian A. Williamson, Jia Wen, John F. Rawls, Scott T. Magness
TX)",
S6390
Etomoxir
,"
MilliporeSigma
(Burlington, MA)",
E1905
-5MG
C75
,"Cayman Chemical (Ann Arbor, MI)",
10005270
Metformin
,"
Cayman Chemical
(Ann Arbor, MI)",
13118
Dimethyl sulfoxide
,"
MilliporeSigma
(Burlington,
(4)
Inhibitors of VPS34 and fatty-acid metabolism suppress SARS-CoV-2 replication
Cell reports
August 3, 2021
Williams CG, Jureka AS, Silvas JA, Nicolini AM, Chvatal SA, Carlson-Stevermer J, Oki J, Holden K, Basler CF.
VPS34 IN-1
(#
17392
),
PIK-III
(#
17002
),
Triacsin C
(#
10007448
),
Orlistat
(#
10005426
),
TOFA
(#
10005263
),
C75
(#
10005270
),
Etomoxir
(#
11969
), Trimetazidine (#
18165
), and
A-922500
(#
10012708
) were purchased from
Cayman Chemical
(5)
Gold Nanoparticle Transforms Activated Cancer-Associated Fibroblasts to Quiescence
ACS Applied Materials & Interfaces
July 24, 2019
Md. Nazir Hossen, Geeta Rao, Anindya Dey, J. David Robertson, Resham Bhattacharya, Priyabrata Mukherjee
(EHU130711) and all trans ratinoic acid (
R2625
) were bought from
Sigma-Aldrich
(St. Louis, MO, USA).
C75
(
10005270
) was purchased from
Cayman chemicals
(Ann Arbor, Michigan, USA). BODIPY 493/503 (
D3922
),
1-pyrenedecanoic acid
(6)
TLR8-Mediated Metabolic Control of Human Treg Function: A Mechanistic Target for Cancer Immunotherapy
Cell metabolism
January 8, 2019
Li L, Liu X, Sanders KL, Edwards JL, Ye J, Si F, Gao A, Huang L, Hsueh EC, Ford DA,
et al
.
19068
; CAS:1113–59-3 Etomoxir,
Cayman Chemical
,Cat#
11969
; CAS:828934–41-4
C75
,
Cayman Chemical
,Cat#
10005270
; CAS:191282–48-1
Orlistat
,
Cayman Chemical
,Cat#
10005426
; CAS:96829–58-2 25-HC,
Cayman Chemical
,Cat#
(7)
Metabolic control of the scaffold protein TKS5 in tissue-invasive, proinflammatory T cells
Nature immunology
September 1, 2017
Shen Y, Wen Z, Li Y, Matteson EL, Hong J, Goronzy JJ, Weyand CM.
96h, as indicated. To
inhibit
FA synthesis or glycolytic breakdown, cells were kept in
C75
(20 μM, #
10005270
,
Cayman Chemical
) or
3PO
(200 nM, #
525330-25MG
,
EMD Millipore
). Transwell migration
assay
CD4+CD45RA+
(8)
Caveolin-1 regulates hormone resistance through lipid synthesis, creating novel therapeutic opportunities for castration-resistant prostate cancer
Oncotarget
July 19, 2016
Theodoros Karantanos et al.
group [11].
Adenovirus
-mediated gene transduction was performed as previously described [12]. C-75 (
10005270
) was purchased from
Cayman
.
RNA interference
Cav-1siRNA6 (SI00299614), Cav-1siRNA7 (SI00 299621),
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(±)-C75 from Cayman Chemical
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$152.00
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