Description
Growth arrest-specific 6, also known as GAS6 is a growth factor that serves as a ligand for members of the Axl subfamily of receptor protein-tyrosine kinases. GAS6 is expressed in hematopoietic tissue. GAS6 function as a direct regulator of osteoclastic function; they give an insight into the role of these vitamin K-dependent ligands in bone resorption in vivo. GAS6 has a potential therapeutic target to minimize graft-versus-host disease (GVHD)