Description
N-terminal GST tagged Src SH3 domain. Src SH3 domain is the SH3 domain of Src tyrosine kinase. SH3 domains are known to bind proline rich peptides. The Src SH3 domain has been expressed as a fusion protein with GST allowing expression in E. coli and purification by affinity chromatography. The native GST-Src-SH3 is the ideal tool for in vitro/in vivo investigations of the behaviour of cellular prions. It may be used for protein-protein interaction studies as well as forin vitro/in vivoconversion studies. The GST-Tag facilitates the protein's application in typical GST pull-down assays