Description
14-3-3 is a general name given to a family of acidic, soluble, ubiquitously expressed 28kDa proteins that are the products of related but separate genes. They are considered isoforms and are named eta (η), gamma (γ), delta/zeta (δ/ξ), alpha/beta (α/β), theta/tau (θ/τ), sigma (σ) or epsilon (ε). Interactions are generally mediated by phosphorylation of specific binding sites in the target proteins