Recombinant Mouse Siglec-2/CD22 Fc Chimera Protein, CF 2296-SL-050 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Mouse Siglec-2/CD22 Fc Chimera Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $479.00Supplier Page View Company Product Page
Catalog Number2296-SL-050
SpeciesMouse
Molecule NameSiglec-2/CD22
Size50 ug
FormatLyophilized from a 0.2 µm filtered solution in PBS
NCBI Full Gene NameCD22 antigen
NCBI Gene AliasesA530093D23, Lyb-8, Lyb8
Purity>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 140-150 kDa, reducing conditions
Theoretical: 103 kDa (monomer)
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemNS0-derived Recombinant Mouse Siglec-2/CD22 Fc Chimera Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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(1) CD22 blockade restores homeostatic microglial phagocytosis in ageing brainsNatureApril 1, 2019Pluvinage JV, Haney MS, Smith BAH, Sun J, Iram T, Bonanno L, Li L, Lee DP, Morgens DW, Yang AC, et al.

(2) Transcriptional programs of lymphoid tissue capillary and high endothelium reveal control mechanisms for lymphocyte homingNature immunologyOctober 1, 2014Lee M, Kiefel H, LaJevic MD, Macauley MS, Kawashima H, O'Hara E, Pan J, Paulson JC, Butcher EC.

(3) Broad and direct interaction between TLR and Siglec families of pattern recognition receptors and its regulation by Neu1eLifeSeptember 3, 2014Chen GY, Brown NK, Wu W, Khedri Z, Yu H, Chen X, van de Vlekkert D, D'Azzo A, Zheng P, Liu Y.

Recombinant Mouse Siglec-2/CD22 Fc Chimera Protein, CF from R&D Systems, a Bio-Techne Brand