Recombinant Human Integrin alpha 3 beta 1/VLA-3 Protein, CF 2840-A3-050 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human Integrin alpha 3 beta 1/VLA-3 Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $602.00Supplier Page View Company Product Page
Catalog Number2840-A3-050
SpeciesHuman
FormatLyophilized from a 0.2 µm filtered solution in Tris-Citrate and NaCl
Size50 ug
Molecule NameIntegrin alpha 3 beta 1/VLA-3
NCBI Full Gene Nameintegrin subunit alpha 3, integrin subunit beta 1, aldehyde dehydrogenase 9 family member A1
NCBI Gene AliasesMSK12, CD49C, VLAB, JEB7, VL3A, GAP-B3, MSK18, ILNEB, VLA3a, VCA-2, VLA-BETA, E3, TMABALDH, CD29, FNRB, GPIIA, FRP-2, GAPB3, ALDH9, ALDH4, ALDH7, TMABADH, MDF2, TMABA-DH
Purity>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 150 kDa and 125 kDa, reducing conditions
Theoretical: 110.5 kDa (Integrin alpha 3), 82.3 kDa (Integrin ÃŸ1)
ApplicationsBinding Activity
Conjugate/TagUnconjugated
Source/Expression SystemCHO-derived Recombinant Human Integrin alpha 3 beta 1/VLA-3 Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) A recombinant technique for mapping functional sites of heterotrimeric collagen helices: Collagen IV CB3 fragment as a prototype for integrin bindingThe Journal of biological chemistryJuly 1, 2023Boudko SP, Konopka EH, Kim W, Taga Y, Mizuno K, Springer TA, Hudson BG, Moy TI, Lin FY.1 mM CaCl2). The human α3β1 protein used in the assays was purchased from R&D Systems (catalog no.: 2840-A3-050). FP assays In the FP Kd assay, dilution series of the purified integrin proteins were incubated in

(2) The effects of inhibition and siRNA knockdown of collagen-binding integrins on human umbilical vein endothelial cell migration and tube formationScientific reportsDecember 14, 2022Hunter EJ, Hamaia SW, Kim PS, Malcor JM, Farndale RW.

(3) An innovative strategy to identify new targets for delivering antibodies to the brain has led to the exploration of the integrin familyPloS oneJanuary 1, 2022Cegarra C, Cameron B, Chaves C, Dabdoubi T, Do TM, Genêt B, Roudières V, Shi Y, Tchepikoff P, Lesuisse D.

(4) Targeted Phage Display-based Pulmonary Vaccination in Mice and Non-human PrimatesMed (New York, N.Y.)March 12, 2021Staquicini DI, Barbu EM, Zemans RL, Dray BK, Staquicini FI, Dogra P, Cardó-Vila M, Miranti CK, Baze WB, Villa LL, et al.Peptides, and Recombinant Proteins","Chemicals, Peptides, and Recombinant Proteins" α3β1,R&D Systems,Cat# 2840-A3-050 α6β1,R&D Systems,Cat# 7809-A6-050 α6β4,R&D Systems,Cat# 5497-A6-050 NRP-1,R&D Systems,Cat# 3870-N1-025 SDC-1,R&D Systems

(5) Nonimmune cell-derived ICOS ligand functions as a renoprotective αvβ3 integrin-selective antagonistThe Journal of clinical investigationApril 1, 2019Koh KH, Cao Y, Mangos S, Tardi NJ, Dande RR, Lee HW, Samelko B, Altintas MM, Schmitz VP, Lee H, et al.

(6) LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltrationNatureOctober 1, 2018Deng M, Gui X, Kim J, Xie L, Chen W, Li Z, He L, Chen Y, Chen H, Luo W, et al.integrin-α2β1 (5698-AB-050, R&D systems), integrin-α2β3 (7148-AB-025, R&D systems), integrin-α3β1 (2840-A3–050, R&D systems), integrin-α4β1 (5668-A4–050, R&D systems), integrin-α4β7 (5397-A3–050, R&D systems), integrin-α5β1

(7) NELL-1 in the treatment of osteoporotic bone lossNature communicationsJune 17, 2015James AW, Shen J, Zhang X, Asatrian G, Goyal R, Kwak JH, Jiang L, Bengs B, Culiat CT, Turner AS, et al.prepared in a 96-well plate in triplicate containing 2 μg NELL-1 and/or 1 μg integrin α3β1 (R&D Systems, 2840-A3-050) and freshly diluted SYPRO orange in PBS buffer (0.01 M, pH 7.4) with the total volume of 15 μl, and

(8) Integrin α2β1 mediates tyrosine phosphorylation of vascular endothelial cadherin induced by invasive breast cancer cellsThe Journal of biological chemistrySeptember 21, 2012Haidari M, Zhang W, Caivano A, Chen Z, Ganjehei L, Mortazavi A, Stroud C, Woodside DG, Willerson JT, Dixon RA.

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Recombinant Human Integrin alpha 3 beta 1/VLA-3 Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human Integrin alpha 3 beta 1/VLA-3 Protein, CF from R&D Systems, a Bio-Techne Brand

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