BACE-1 Protein 2976-AS-050 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemBACE-1 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $454.00Supplier Page View Company Product Page
Catalog Number2976-AS-050
SpeciesMouse
FormatLyophilized from a 0.2 µm filtered solution in Tris and NaCl
Molecule NameBACE-1
Size50 ug
NCBI Full Gene Namebeta-site APP cleaving enzyme 1, beta-secretase 1
NCBI Gene AliasesHSPC104, BACE, ASP2, Bace
Purity>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
ApplicationsEnzyme Activity
Conjugate/TagUnconjugated
Source/Expression SystemNS0-derived Recombinant Mouse BACE-1 Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Sizes Available: 50 ug

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) The Alzheimer's disease-linked protease BACE1 modulates neuronal IL-6 signaling through shedding of the receptor gp130Molecular neurodegenerationFebruary 21, 2023Müller SA, Shmueli MD, Feng X, Tüshaus J, Schumacher N, Clark R, Smith BE, Chi A, Rose-John S, Kennedy ME, et al.

(2) Development of a specific ELISA to measure BACE1 levels in human tissuesJournal of neuroscience methodsOctober 30, 2011Gonzales A, Decourt B, Walker A, Condjella R, Nural H, Sabbagh MN.from Enzo Life Sciences (BML-SE531) and R&D Systems (931-AS-050); mouse recombinant BACE1 (R&D Systems 2976-AS-050); human recombinant renin (Enzo life Sciences ALX-201-256); cathepsin D from human liver (Sigma–Aldrich

(3) HtrA2 regulates beta-amyloid precursor protein (APP) metabolism through endoplasmic reticulum-associated degradationThe Journal of biological chemistrySeptember 21, 2007Huttunen HJ, Guénette SY, Peach C, Greco C, Xia W, Kim DY, Barren C, Tanzi RE, Kovacs DM.

(4) The ACAT inhibitor CP-113,818 markedly reduces amyloid pathology in a mouse model of Alzheimer's diseaseNeuronOctober 14, 2004Hutter-Paier B, Huttunen HJ, Puglielli L, Eckman CB, Kim DY, Hofmeister A, Moir RD, Domnitz SB, Frosch MP, Windisch M, et al.

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BACE-1 Protein from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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BACE-1 Protein from R&D Systems, a Bio-Techne Brand

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