Recombinant Human IL-4 (carrier-free) 574008 from BioLegend

Product Specs
ItemRecombinant Human IL-4 (carrier-free)
CompanyBioLegend
Price $2,109.00Supplier Page View Company Product Page
Catalog Number574008
ApplicationsBioassay
Size500 µg
Gene Nameinterleukin 4
NCBI Gene AliasesBCGF-1, BCGF1, BSF-1, BSF1, IL-4
NCBI Full Gene Nameinterleukin 4
FormatThe protein was 0.22 µm filtered in PBS, pH 7.2
Molecule NameIL-4
SpeciesHuman
Concentration10 and 25 µg sizes are bottled at 200 µg/mL. 100 µg size and larger sizes are lot-specific and bottled at the concentration indicated on the vial. To obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool

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BioLegend

8999 BioLegend Way

San Diego, California 92121

United States

Phone: 1-877-246-5343 Toll-Free, USA & Canada
1-858-768-5800 International
Fax: 1-877-455-9587

Company Profile

Website: biolegend.com

(1) Super-adjuvant nanoparticles for platform cancer vaccinationCell Reports MedicineOctober 21, 2025Griffin I. Kane, Tiana E. Naylor, Ellis F. Lusi, Meghan L. Brassil, Kim Wigglesworth, Ronnie W. Dinnell, Miranda B. Diaz-Infante, Leah M. Whiteman, John Lukas, Megan Winkler, et al.Recombinant Human GM-CSF (carrier-free) (BioLegend # 572904), Recombinant Human IL-4 (carrier-free) (BioLegend # 574006). On day 2, 1 mL of fresh media was added to the culture. On day 5, 1mL of supernatant was removed and

(2) Engineered CD147-CAR macrophages for enhanced phagocytosis of cancersCancer Immunology, ImmunotherapyJuly 2, 2024Koollawat Chupradit, Saitong Muneekaew, Methichit Wattanapanitchmacrophages were cultured in a complete RPMI-1640 medium supplemented with 25 ng/mL IL-4 (Biolegend, 574008) and 25 ng/mL IL-13 (Biolegend, 571102). The cells were further cultured for 72 h. Afterward, the cells

(3) M2 macrophages participate in ILC2 activation induced by Helicobacter pylori infectionGut microbesJanuary 1, 2024Peng R, Xu C, Zhang L, Liu X, Peng D, Chen X, Liu D, Li R.molecular markers (CD68 and CD11b) were analyzed by flow cytometry (data not shown). IL-4 (Biolegend, #574006) and IL-13 (Biolegend, #571106) were added to the cell culture medium (10 ng/ml, 48 h). The M1 macrophages

(4) Multimodal, broadly neutralizing antibodies against SARS-CoV-2 identified by high-throughput native pairing of BCRs from bulk B cellsCell chemical biologyNovember 16, 2023Keitany GJ, Rubin BER, Garrett ME, Musa A, Tracy J, Liang Y, Ebert P, Moore AJ, Guan J, Eggers E, et al.,Thermo Fisher Scientific,Cat#10010072 Blocker BSA 10X in PBS,Thermo Fisher Scientific,Cat#PI37525 Human Recombinant IL-4,BioLegend,Cat#574008 "CD40L, carrier free, human",R&D Systems,Cat#6420-CL-025/CF "IL-2 (human, carrier free)",Biolegend,Cat#589106 BioGlo

(5) Ubc9 regulates the expression of MHC II in dendritic cells to enhance DSS-induced colitis by mediating RBPJ SUMOylationCell death & diseaseNovember 13, 2023Zhang J, Chen L, Xu Q, Zou Y, Sun F, Zhou Q, Luo X, Li Y, Chen C, Zhang S, et al.

(6) Differential Immunomodulatory Effects of Head and Neck Cancer-Derived Exosomes on B Cells in the Presence of ATPInternational journal of molecular sciencesNovember 21, 2022Coray M, Göldi V, Schmid L, Benecke L, Figueiró F, Muller L.

(7) Supply Chain Disruptions During COVID-19 Pandemic Uncover Differences in Keratinocyte Culture MediaJID InnovNovember 1, 2022Moran MC, Pope EM, Brewer MG, Beck LA.

(8) Glycerol monolaurate inhibition of human B cell activationScientific reportsAugust 5, 2022Fosdick MG, Loftus S, Phillips I, Zacharias ZR, Houtman JCD.

(9) PD-1 and ICOS coexpression identifies tumor-reactive CD4+ T cells in human solid tumorsThe Journal of clinical investigationJune 15, 2022Duhen R, Fesneau O, Samson KA, Frye AK, Beymer M, Rajamanickam V, Ross D, Tran E, Bernard B, Weinberg AD, et al.

(10) PD-L1 blockade restores CAR T cell activity through IFN-γ-regulation of CD163+ M2 macrophagesJournal for immunotherapy of cancerJune 1, 2022Yamaguchi Y, Gibson J, Ou K, Lopez LS, Ng RH, Leggett N, Jonsson VD, Zarif JC, Lee PP, Wang X, et al.

(11) MHC class II molecules on pancreatic cancer cells indicate a potential for neo-antigen-based immunotherapyOncoimmunologyJanuary 1, 2022Baleeiro RB, Bouwens CJ, Liu P, Di Gioia C, Dunmall LSC, Nagano A, Gangeswaran R, Chelala C, Kocher HM, Lemoine NR, et al.cultures were supplemented with 50 ng/mL recombinant human GM-CSF (#572904; BioLegend) and 50 ng/mL IL-4 (#574006; BioLegend). The cultures were maintained at 37°C in humidified atmosphere with 5% CO2. For DCs maturation,

(12) Interleukins 4 and 13 drive lipid abnormalities in skin cells through regulation of sex steroid hormone synthesisProceedings of the National Academy of Sciences of the United States of AmericaSeptember 21, 2021Zhang C, Chinnappan M, Prestwood CA, Edwards M, Artami M, Thompson BM, Eckert KM, Vale G, Zouboulis CC, McDonald JG, et al.

(13) Invariant Natural Killer T cells coordinate removal of senescent cellsMedAugust 13, 2021Arora S, Thompson PJ, Wang Y, Bhattacharyya A, Apostolopoulou H, Hatano R, Naikawadi RP, Shah A, Wolters PJ, Koliwad S, et al.

(14) Vaccination reshapes the virus-specific T cell repertoire in unexposed adultsImmunityJune 8, 2021Pan YG, Aiamkitsumrit B, Bartolo L, Wang Y, Lavery C, Marc A, Holec PV, Rappazzo CG, Eilola T, Gimotty PA, et al.Recombinant Human GM-CSF (carrier-free),Biolegend,Cat# 572904 Recombinant Human IL-4 (carrier-free),Biolegend,Cat# 574006 YF23 (NS3 313 - 327); Seq: ESATILMTATPPGTS,This paper,N/A YF25 (NS3 448 - 462); Seq: KGPLRISASSAAQRR,This

(15) Synergistic Action of Diclofenac with Endotoxin-Mediated Inflammation Exacerbates Intestinal Injury in VitroACS infectious diseasesApril 9, 2021Chen WLK, Suter E, Miyazaki H, Velazquez J, Lauffenburger DA, Griffith LG, Carrier RL.

(16) Human physiomimetic model integrating microphysiological systems of the gut, liver, and brain for studies of neurodegenerative diseasesScience advancesJanuary 1, 2021Trapecar M, Wogram E, Svoboda D, Communal C, Omer A, Lungjangwa T, Sphabmixay P, Velazquez J, Schneider K, Wright CW, et al.

(17) Visualizing Cellular Dynamics and Protein Localization in 3D CollagenSTAR protocolsDecember 18, 2020Koh WH, Zayats R, Lopez P, Murooka TT.Proteins" ,, Human recombinant IL-2,Peprotech,Cat #200-02 Human recombinant IL-4,Biolegend,Cat #574008 Human recombinant GM-CSF,Biolegend,Cat #578606 Ficoll-Hypaque solution,GE Healthcare,Cat #17-1440-03 LPS

(18) Monocyte metabolic reprogramming promotes pro-inflammatory activity and Staphylococcus aureus biofilm clearancePLoS pathogensMarch 1, 2020Yamada KJ, Heim CE, Xi X, Attri KS, Wang D, Zhang W, Singh PK, Bronich TK, Kielian T.

(19) Escherichia coli lipopolysaccharide may affect the endothelial barrier and IL-10 expression of apolipoprotein B100-pulsed dendritic cellsAPMIS : acta pathologica, microbiologica, et immunologica ScandinavicaJanuary 1, 2020Chalubinski M, Wojdan K, Luczak E, Gorzelak-Pabis P, Kluszczynska K, Borowiec M, Gajewski A, Rudnicka K, Chmiela M, Broncel M.

(20) Enhanced Human T Lymphocyte Antigen Priming by Cytokine-Matured Dendritic Cells Overexpressing Bcl-2 and IL-12Frontiers in cell and developmental biologyJanuary 1, 2020Zhang H, Wang Y, Wang QT, Sun SN, Li SY, Shang H, He YW.

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Recombinant Human IL-4 (carrier-free) from BioLegend

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Recombinant Human IL-4 (carrier-free) from BioLegend

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