Recombinant Mouse TLR2 Fc Chimera Protein, CF 1530-TR-050 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Mouse TLR2 Fc Chimera Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $479.00Supplier Page View Company Product Page
Catalog Number1530-TR-050
FormatLyophilized from a 0.2 µm filtered solution in PBS, NaCl and PEG 3350
SpeciesMouse
Source/Expression SystemSf 21 (baculovirus)-derived Recombinant Mouse TLR2 Fc Chimera Protein, CF
Size50 ug
NCBI Full Gene Nametoll-like receptor 2
NCBI Gene AliasesLy105
Purity>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 92 kDa, reducing conditions
Theoretical: 90.4 kDa (monomer)
ApplicationsBinding Activity
Conjugate/TagUnconjugated
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution
Molecule NameTLR2

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(1) HBeAg mediates inflammatory functions of macrophages by TLR2 contributing to hepatic fibrosisBMC medicineOctober 15, 2021Xie X, Lv H, Liu C, Su X, Yu Z, Song S, Bian H, Tian M, Qin C, Qi J, et al.

(2) AIM/CD5L attenuates DAMPs in the injured brain and thereby ameliorates ischemic strokeCell reportsSeptember 14, 2021Maehara N, Taniguchi K, Okuno A, Ando H, Hirota A, Li Z, Wang CT, Arai S, Miyazaki T.

(4) Calpains Released by T Lymphocytes Cleave TLR2 To Control IL-17 ExpressionJournal of immunology (Baltimore, Md. : 1950)January 1, 2016Perez J, Dansou B, Hervé R, Levi C, Tamouza H, Vandermeersch S, Demey-Thomas E, Haymann JP, Zafrani L, Klatzmann D, et al.

(5) Structural basis for inhibition of TLR2 by staphylococcal superantigen-like protein 3 (SSL3)Proceedings of the National Academy of Sciences of the United States of AmericaSeptember 1, 2015Koymans KJ, Feitsma LJ, Brondijk TH, Aerts PC, Lukkien E, Lössl P, van Kessel KP, de Haas CJ, van Strijp JA, Huizinga EG.

(6) Soluble TLR2 reduces inflammation without compromising bacterial clearance by disrupting TLR2 triggeringJournal of immunology (Baltimore, Md. : 1950)July 1, 2009Raby AC, Le Bouder E, Colmont C, Davies J, Richards P, Coles B, George CH, Jones SA, Brennan P, Topley N, et al.

Recombinant Mouse TLR2 Fc Chimera Protein, CF from R&D Systems, a Bio-Techne Brand