Recombinant Human IL-36Ra/IL-1F5 Protein, CF 1275-IL-025/CF from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human IL-36Ra/IL-1F5 Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $408.00Supplier Page View Company Product Page
Catalog Number1275-IL-025/CF
SpeciesHuman
Molecule NameIL-36Ra/IL-1F5
FormatLyophilized from a 0.2 µm filtered solution in PBS
Source/Expression SystemE. coli-derived Recombinant Human IL-36Ra/IL-1F5 Protein, CF
Size25 ug
NCBI Full Gene Nameinterleukin 36 receptor antagonist
NCBI Gene AliasesFIL1, IL-36Ra, IL1L1, PSORS14, IL36RA, FIL1D, PSORP, IL1HY1, FIL1(DELTA), IL1RP3, IL1F5
Purity>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular Weight17 kDa
ApplicationsBioactivity
Conjugate/TagUnconjugated
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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(1) IL-36G promotes cancer-cell intrinsic hallmarks in human gastric cancer cellsCytokineJuly 1, 2022Le N, Luk I, Chisanga D, Shi W, Pang L, Scholz G, Mariadason J, Ernst M, Huynh J.

(2) Interleukin (IL)-17/IL-36 axis participates to the crosstalk between endothelial cells and keratinocytes during inflammatory skin responsesPloS oneJanuary 1, 2020Mercurio L, Failla CM, Capriotti L, Scarponi C, Facchiano F, Morelli M, Rossi S, Pagnanelli G, Albanesi C, Cavani A, et al.

(3) IL-38 has an anti-inflammatory action in psoriasis and its expression correlates with disease severity and therapeutic response to anti-IL-17A treatmentCell death & diseaseOctober 30, 2018Mercurio L, Morelli M, Scarponi C, Eisenmesser EZ, Doti N, Pagnanelli G, Gubinelli E, Mazzanti C, Cavani A, Ruvo M, et al.

(4) Interleukin-36 receptor mediates the crosstalk between plasma cells and synovial fibroblastsEuropean journal of immunologyDecember 1, 2017Schmitt V, Hahn M, Kästele V, Wagner O, Wiendl M, Derer A, Taddeo A, Hahne S, Radbruch A, Jäck HM, et al.

(6) Structural and Functional Attributes of the Interleukin-36 ReceptorThe Journal of biological chemistryAugust 5, 2016Yi G, Ybe JA, Saha SS, Caviness G, Raymond E, Ganesan R, Mbow ML, Kao CC.

(7) Signal Transduction and Intracellular Trafficking by the Interleukin 36 ReceptorThe Journal of biological chemistrySeptember 25, 2015Saha SS, Singh D, Raymond EL, Ganesan R, Caviness G, Grimaldi C, Woska JR Jr, Mennerich D, Brown SE, Mbow ML, et al.

(8) IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonistProceedings of the National Academy of Sciences of the United States of AmericaFebruary 21, 2012van de Veerdonk FL, Stoeckman AK, Wu G, Boeckermann AN, Azam T, Netea MG, Joosten LA, van der Meer JW, Hao R, Kalabokis V, et al.

Recombinant Human IL-36Ra/IL-1F5 Protein, CF