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Recombinant Human MTH1 protein (His tag N-Terminus)
Recombinant Human MTH1 protein (His tag N-Terminus) from Abcam
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Citations:
(2)
Supplier Page
Supplier Page from
Abcam for
Recombinant Human MTH1 protein (His tag N-Terminus)
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Recombinant Human MTH1 protein (His tag N-Terminus)
Company
Abcam
Price
Supplier Page
View Company Product Page
Catalog Number
ab99390
Applications
Mass Spec, SDS-PAGE
Format
ab99390 is purified using conventional chromatography techniques
Size
100 µg
Concentration
1 mg/ml
NCBI Gene Aliases
MTH1
Gene Name
NUDT1
Source/Expression System
Escherichia coli
Activity
Inactive
Species
Human
Research Area
Oncology
NCBI Full Gene Name
nudix hydrolase 1
Type
Proteins
Molecule Name
NUDT1
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Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB2 0AX
United Kingdom
Phone
: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600
Company Profile
Website:
http://www.abcam.com
Citations (2)
(1)
The Existence of MTH1-independent 8-oxodGTPase Activity in Cancer Cells as a Compensatory Mechanism against On-target Effects of MTH1 Inhibitors
Molecular cancer therapeutics
February 1, 2020
Samaranayake GJ, Troccoli CI, Zhang L, Huynh M, Jayaraj CJ, Ji D, McPherson L, Onishi Y, Nguyen DM, Robbins DJ,
et al
.
(SGC). Recombinant
MTH1
and
MTH2
proteins Recombinant human MTH1 (
NUDT1
) was purchased from
Abcam
(
ab99390
). Recombinant human
MTH2
(
NUDT15
) was obtained commercially from
Origene
,
TP310477
. The recombinant
(2)
Increased MTH1-specific 8-oxodGTPase activity is a hallmark of cancer in colon, lung and pancreatic tissue
DNA repair
November 1, 2019
McPherson LA, Troccoli CI, Ji D, Bowles AE, Gardiner ML, Mohsen MG, Nagathihalli NS, Nguyen DM, Robbins DJ, Merchant NB,
et al
.
allow the endogenous
MTH1
to cleave the ARGO probe and then placed on ice. Recombinant
MTH1
(
Abcam
ab99390
) was used to generate a standard curve and a reaction containing all reagents except lysate or recombinant
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Recombinant Human MTH1 protein (His tag N-Terminus) from Abcam
Supplier Page
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