Fig 1: Effects of WZS08 on plasma glucose and lipid parameters. Serum was collected at the end of experiment in the fast state. Panel A, glucose; Panel B, serum insulin; Panel C, HOMA-IR; Panel D, serum TG (D); Panel E, serum cholesterol; Panel F, serum LDL (F); Panel G, serum HDL. HOMA-IR was obtained by formula: HOMA-IR = Insulin (mUI/L) × serum glucose (mmol/L)/22.4. Mean ± SEM, n = 20 (animals). There are significant differences between the two groups with different alphabets (p < 0.05).
Fig 2: mRNA and protein levels and of lipogenesis and lipid metabolism related gene. Panel A, Acs2, Ldlr, Hsd11b1, Plin2, and Plin3. Mean ± SEM, n = 13 (randomly selected samples). Panel B, Western blot for 11ß-HSD1 and ACS2 and the protein level of 11ß-HSD1 and ACS2 relative to ACTB. Mean ± SEM, n = 3 (randomly selected samples). There are significant differences between the two groups with different alphabets (p < 0.05).
Supplier Page from Abcam for HSD11B1 peptide