Human Interferon Alpha A (Alpha 2a), carrier-free 11101-2 from PBL Assay Science

Product Specs
ItemHuman Interferon Alpha A (Alpha 2a), carrier-free
CompanyPBL Assay Science
Price $340.00Supplier Page View Company Product Page
Catalog Number11101-2
Purity>95%
SpeciesHuman
Source/Expression SystemE.coli
ActivityActivity: 8.7 x 10⁸ u/mg
FormatPBS
Molecule NameIFN-Alpha 2a (IFN-Alpha A)
Size20 µg
Gene Nameinterferon, alpha 2
TypeProtein
Molecular Weight19.2 kDa
NCBI Full Gene Nameinterferon alpha 2
NCBI Gene AliasesIFN-alpha-2, IFN-alphaA, IFNA, IFNA2B, leIF A

Specifications/Features

Protein Specific Information:
, carrier-free

Additional Product Information

Protein/Peptide:
IFN Alpha A (Alpha 2a)

Protein/Peptide Species:
Human

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PBL Assay Science

131 Ethel Road West. Suite 6

Piscataway, New Jersey

United States

Phone: 1-877-725-8881
1-732-777-9123
1-732-777-9141

Company Profile

Website: www.pblassaysci.com

(1) A scalable proteogenomic framework for dissecting phospho-signaling pathways in primary immune cellsbioRxivOctober 14, 2025Christian M. Beusch, Carolyn Morningstar, Marc Semaan, Christopher M. Monaco, Sarah Welbourn, Hailey Swaldi, Jae-Kyun Ko, Devin Kenney, Alexander Sousa, Holt Sakai, et al.volume of 2 mL. Cells were stimulated with 100 IU/mL IFN-β, 1 nM IFN-α2a (PBL assay Science; Cat. #11101–2), 1 nM IFN-γ (PBL assay Science; Cat. #11500–1), 100 ng/mL lipopolysaccharide (LPS) (InvivoGen; Cat.

(2) Contrasting interferon-mediated antiviral responses in human lung adenocarcinoma cellsJournal of VirologyJune 17, 2025Matthew Esparza, Sara S. El Zahed, Umut Karakus, Hanspeter Niederstrasser, Boning Gao, Kimberly Batten, Jerry W. Shay, Bruce Posner, Fred R. Hirsch, Luc Girard, et al.DNA visualization. Cytokines used in this study include human IFN-α 2a (Alpha A, PBL Assay Science, 11101-2) and human IFN-λ 1 (PBL Assay Science, 11826-1). Primary antibodies used for western blot include anti-phospho-STAT1 (Tyr701

(3) A genome-wide arrayed CRISPR screen identifies PLSCR1 as an intrinsic barrier to SARS-CoV-2 entry that recent virus variants have evolved to resistPLoS biologySeptember 1, 2024Le Pen J, Paniccia G, Kinast V, Moncada-Velez M, Ashbrook AW, Bauer M, Hoffmann HH, Pinharanda A, Ricardo-Lax I, Stenzel AF, et al.day, the media was aspirated and replaced with 2 mL of DMEM with or without 0.5 nM IFN-α2a (PBL, cat. 11101-2), and the cells were incubated at 37°C. After 24 hours, the cells were harvested in 500 μL TRIzol. N

(4) An RNA-based system to study hepatitis B virus replication and evaluate antiviralsScience advancesApril 14, 2023Yu Y, Schneider WM, Kass MA, Michailidis E, Acevedo A, Pamplona Mosimann AL, Bordignon J, Koenig A, Livingston CM, van Gijzel H, et al.Infectious Diseases, NIH. Interferons Human IFN-α2a was purchased from PBL Assay Science (catalog no. 11101-2), and human IFN-λ3 was purchased from R&D Systems (catalog no. 5259-IL-025). Antisense oligos BPV

(5) The main protease of SARS-CoV-2 cleaves histone deacetylases and DCP1A, attenuating the immune defense of the interferon-stimulated genesThe Journal of biological chemistryMarch 1, 2023Song L, Wang D, Abbas G, Li M, Cui M, Wang J, Lin Z, Zhang XE.(Life Technologies) according to the manufacturer’s instructions. Cells were treated with IFN-α2a (catalog no. 11101–2; PBL Assay Science) at 1000 units/ml, MG132 (MCE) at 20 μM, Z-VAD-FMK (APE x BIO) at 20 μM, and NH4Cl

(6) Intraperitoneal monocytes plus interferons as a novel cellular immunotherapy for ovarian cancer: mechanistic characterization and results from a phase I clinical trialClinical Cancer ResearchJanuary 17, 2023Daniel S. Green, Franklin Ning, Anna Duemler, Timothy G. Myers, Kathryn Trewhitt, Irene Ekwede, Ann McCoy, Nicole Houston, Jung-min Lee, Stanley Lipkowitz, et al.that had been covalently coupled to 2.5ug recombinant human IFNα (PBL Biomedical Laboratories; catalog 11101–2) or IFNγ (R&D Systems; catalog 285-IF-100/CF). Beads were washed then incubated with 1 ug/mL PE-labeled

(7) Intraperitoneal monocytes plus interferons as a novel cellular immunotherapy for ovarian cancer: mechanistic characterization and results from a phase I clinical trialClin Cancer ResJanuary 17, 2023Daniel S. Green, Franklin Ning, Anna Duemler, Timothy G Myers, Kathryn Trewhitt, Irene Ekwede, Ann McCoy, Nicole Houston, Jung-min Lee, Stanley Lipkowitz, et al.that had been covalently coupled to 2.5ug recombinant human IFNα (PBL Biomedical Laboratories; catalog 11101–2) or IFNγ (R&D Systems; catalog 285-IF-100/CF). Beads were washed then incubated with 1 ug/mL PE-labeled

(8) Association between anti-interferon-alpha autoantibodies and COVID-19 in systemic lupus erythematosusmedRxivAugust 19, 2022Sarthak Gupta, Shuichiro Nakabo, Jun Chu, Sarfaraz Hasni, Mariana J. Kaplanovernight at 4°C with 50μL of 2μg/mL recombinant human IFNα (rhIFNα) (PBL assay science, Inc catalog # 11101–2). Plates were then washed, blocked, washed again and incubated with 1:50 dilution of plasma samples

(9) SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cellsCell reportsMarch 8, 2022Hammer Q, Dunst J, Christ W, Picarazzi F, Wendorff M, Momayyezi P, Huhn O, Netskar HK, Maleki KT, García M, et al.Human IL-15 Recombinant Protein,ThermoFisher,PHC9151 Recombinant Human IFN-Alpha2a,PBL Assay Science,11101-2 ,, Critical commercial assays,Critical commercial assays,Critical commercial assays ,, BD Cytofix/Cytoperm™,BD

(10) Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CL^pro substrate degradomeCell reportsOctober 26, 2021Pablos I, Machado Y, de Jesus HCR, Mohamud Y, Kappelhoff R, Lindskog C, Vlok M, Bell PA, Butler GS, Grin PM, et al.(Cytiva),Sigma,Cat#GE17-5247-01 HPG-ALD 100K polymer,UBC Flintbox,www.bit.ly/3iHPs8P IFN-α2a (carrier free),PBL Assay Science,Cat#11101-2 IFN-β1a (carrier free),PBL Assay Science,Cat#11410-2 Imperial protein stain,Thermo Fisher Scientific,Cat#24617 "importin

(11) Schlafen 11 expression in human acute leukemia cells with gain-of-function mutations in the interferon-JAK signaling pathwayiScienceOctober 22, 2021Murai Y, Jo U, Murai J, Fukuda S, Takebe N, Pommier Y.,Thermo Fisher Scientific,Cat# PHC4031 Human interferon-alpha a protein (alpha 2a),PBL assay science,Cat# 11101-2 Cerdulatinib,MedChemExpress,Cat# HY-15999 Ruxolitinib,MedChemExpress,Cat# HY-50856 Tofacitinib,MedChemExpress,Cat#

(12) Comment on 'AIRE-deficient patients harbor unique high-affinity disease-ameliorating autoantibodies'eLifeJune 27, 2019Nils Landegren et al.555397 2 uL/test Recombinant protein Recombinant human interferon-alpha 2 PBL Assay Science Cat # 11101–2 Concentration: 10 ng/mL Recombinant protein Recombinant human interferon-alpha Peprotech Cat# 300–02J Concentration: 10

(13) Comment on 'AIRE-deficient patients harbor unique high-affinity disease-ameliorating autoantibodies'ElifeJune 27, 2019Nils Landegren, Lindsey B Rosen, Eva Freyhult, Daniel Eriksson, Tove Fall, Gustav Smith, Elise M N Ferre, Petter Brodin, Donald Sharon, Michael Snyder, et al.555397 2 uL/test Recombinant protein Recombinant human interferon-alpha 2 PBL Assay Science Cat # 11101–2 Concentration: 10 ng/mL Recombinant protein Recombinant human interferon-alpha Peprotech Cat# 300–02J Concentration: 10

(14) Porcine Deltacoronavirus nsp5 Antagonizes Type I Interferon Signaling by Cleaving STAT2Journal of VirologyMay 15, 2017Xinyu Zhu et al.and pRL-TK. Twenty-four hours after transfection, the cells were stimulated with IFN-␣ (catalog no. 11101-2; PBL Assay Science) for 12 h at a ﬁnal concentration of 1,000 U/ml. The lysed cells were prepared, and

(15) Biallelic JAK1 mutations in immunodeficient patient with mycobacterial infectionNature CommunicationsDecember 23, 2016Davide Eletto et al.U4C-FRT cells or patient fibroblasts along with appropriate control cells upon stimulation with IFN-α (11101–2, PBL) or IFN-γ (IF002, Millipore), in full growth medium at 37 °C. Then, the cells were trypsinized,

(16) IQGAP2 is a novel interferon-alpha antiviral effector gene acting non-conventionally through the NF-κB pathwayJournal of HepatologyNovember 1, 2016Cynthia Brisac et al.after an adsorption period of 4 hours with fresh medium. Human IFN-α2a, from PBL Interferon source (11101-2 and 11100-1), were used at a final concentration of 100 IU/ml in Huh7.5.1 and Huh7.5.1/pNFκB-GFP cells

(17) Broad-spectrum antibodies against self-antigens and cytokines in RAG deficiencyThe Journal of clinical investigationNovember 2, 2015Walter JE, Rosen LB, Csomos K, Rosenberg JM, Mathew D, Keszei M, Ujhazi B, Chen K, Lee YN, Tirosh I, et al.MC10065-01) were covalently coupled to 2.5 μg recombinant human IFN-α (PBL Biomedical Laboratories; catalog 11101-2); IFN-β (PeproTech; catalog 300-02BC); IFN-γ (R&D Systems; catalog 285-IF-100/ CF); IFN-λ1 (eBioscience;

(18) Porcine bocavirus NP1 negatively regulates interferon signaling pathway by targeting the DNA-binding domain of IRF9VirologyNovember 1, 2015Zhang R, Fang L, Wang D, Cai K, Zhang H, Xie L, Li Y, Chen H, Xiao S.24 h after the initial co-transfection, the cells were further stimulated with IFN-α ( Catalog no. 11101-2, PBL assay science) or IFN-β (Catalog no. 300-02BC, Peprotech) for 6 h. Luciferase activity was determined

(19) Interferon Beta and Interferon Alpha 2a Differentially Protect Head and Neck Cancer Cells from Vesicular Stomatitis Virus-Induced OncolysisJournal of VirologyAugust 1, 2015Marlena M. Westcott, Jingfang Liu, Karishma Rajani, Ralph D'Agostino, Douglas S. Lyles, Mercedes Porosnicu

(20) Dissecting the role of COPI complexes in influenza virus infectionJournal of virologyMarch 1, 2013Sun E, He J, Zhuang X.

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Human Interferon Alpha A (Alpha 2a), carrier-free from PBL Assay Science

Description

Specifications/Features

Additional Product Information

PBL Assay Science

Citations (21)

Reviews

Human Interferon Alpha A (Alpha 2a), carrier-free from PBL Assay Science

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