Recombinant Human NKp44 Fc Chimera Protein, CF 2249-NK-050 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human NKp44 Fc Chimera Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $454.00Supplier Page View Company Product Page
Catalog Number2249-NK-050
Size50 ug
ApplicationsBioactivity
FormatLyophilized from a 0.2 µm filtered solution in PBS
Purity>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 61-67 kDa, reducing conditions
Theoretical: 45 kDa (monomer)
Conjugate/TagUnconjugated
SpeciesHuman
Molecule NameNKp44/NCR2
Source/Expression SystemNS0-derived Recombinant Human NKp44 Fc Chimera Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Full Gene Namenatural cytotoxicity triggering receptor 2
NCBI Gene AliasesCD336, LY95, NK-p44, NKP44, dJ149M18.1

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(1) NKp44-based chimeric antigen receptor effectively redirects primary T cells against synovial sarcomaTranslational oncologyNovember 1, 2022Murayama Y, Kasahara Y, Kubo N, Shin C, Imamura M, Oike N, Ariizumi T, Saitoh A, Baba M, Miyazaki T, et al.

(4) Impaired NK-mediated regulation of T-cell activity in multiple sclerosis is reconstituted by IL-2 receptor modulationProceedings of the National Academy of Sciences of the United States of AmericaMay 24, 2016Gross CC, Schulte-Mecklenbeck A, Rünzi A, Kuhlmann T, Posevitz-Fejfár A, Schwab N, Schneider-Hohendorf T, Herich S, Held K, Konjević M, et al.

(6) The regulatory effect of UL-16 binding protein-3 expression on the cytotoxicity of NK cells in cancer patientsScientific reportsAugust 20, 2014Mou X, Zhou Y, Jiang P, Zhou T, Jiang Q, Xu C, Liu H, Zheng T, Yuan G, Zhang Y, et al.

(7) A polysaccharide virulence factor of a human fungal pathogen induces neutrophil apoptosis via NK cellsJournal of immunology (Baltimore, Md. : 1950)June 1, 2014Robinet P, Baychelier F, Fontaine T, Picard C, Debré P, Vieillard V, Latgé JP, Elbim C.

(8) Human cytomegalovirus infection elicits new decidual natural killer cell effector functionsPLoS pathogensJanuary 1, 2013Siewiera J, El Costa H, Tabiasco J, Berrebi A, Cartron G, Le Bouteiller P, Jabrane-Ferrat N.

(10) Tyrosine kinase pathways modulate tumor susceptibility to natural killer cellsThe Journal of clinical investigationJuly 1, 2012Bellucci R, Nguyen HN, Martin A, Heinrichs S, Schinzel AC, Hahn WC, Ritz J.

(11) Engagement of Siglec-7 receptor induces a pro-inflammatory response selectively in monocytesPloS oneJanuary 1, 2012Varchetta S, Brunetta E, Roberto A, Mikulak J, Hudspeth KL, Mondelli MU, Mavilio D.

(12) Direct binding of human NK cell natural cytotoxicity receptor NKp44 to the surfaces of mycobacteria and other bacteriaInfection and immunityApril 1, 2008Esin S, Batoni G, Counoupas C, Stringaro A, Brancatisano FL, Colone M, Maisetta G, Florio W, Arancia G, Campa M.

(13) Bortezomib down-regulates the cell-surface expression of HLA class I and enhances natural killer cell-mediated lysis of myelomaBloodFebruary 1, 2008Shi J, Tricot GJ, Garg TK, Malaviarachchi PA, Szmania SM, Kellum RE, Storrie B, Mulder A, Shaughnessy JD Jr, Barlogie B, et al.

Recombinant Human NKp44 Fc Chimera Protein, CF from R&D Systems, a Bio-Techne Brand