Universal Type I Interferon 11200-2 from PBL Assay Science

Product Specs
ItemUniversal Type I Interferon
CompanyPBL Assay Science
Price $630.00Supplier Page View Company Product Page
Catalog Number11200-2
Purity>95%
SpeciesHuman
Size1 x 106 Units
FormatPBS + 0.1% BSA
Molecule NameIFN-Alpha A/D hybrid
Source/Expression SystemE.coli
ActivityActivity: 1.0 x 10⁸ u/mg
Gene NameNotch
TypeProtein
Molecular Weight19.4 kDa

Additional Product Information

Protein/Peptide:
IFN, Universal Type I (IFN Alpha A/D (BglII))

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PBL Assay Science

131 Ethel Road West. Suite 6

Piscataway, New Jersey

United States

Phone: 1-877-725-8881
1-732-777-9123
1-732-777-9141

Company Profile

Website: www.pblassaysci.com

(1) Development of immortalized Callithrix jacchus kidney cell lines supporting infection with a panel of virusesPLoS OneMarch 2, 2026Sabine Gärtner, Pamela Stomberg, Stefan Pöhlmann, Michael Winklercells/well. The next day, the cells were either left untreated, treated with pan-IFN (PBL Assay Science 11200–2, Piscataway, NJ, USA) at 100 U/mL, or infected with VSV ncp* at MOI 0.1 [46]. Human pan-IFN is a recombinant

(2) Essentiality and dynamic expression of the human tRNA pool during viral infectionMolecular Systems BiologyJanuary 20, 2026Noa Aharon-Hefetz, Michal Schwartz, Einav Aharon, Noam Stern-Ginossar, Orna Dahan, Yitzhak Pilpel,Biological Industries,01-052-1A RPMI,Thermo Fisher,11875093 Fetal bovine serum (FBS),Life Technologies,26-140-095 Interferon α (IFNα),PBL,11200-2 Interferon β (IFNβ),Peprotech,300-02BC-20 ruxolitinib,InvivoGen,941678-49-5 jetPEI transfection reagent,Polyplus,101-10N Hexadimethrine

(3) Single-cell atlas of hepatitis C virus inoculated tree shrew liver reveals immune activation, metabolic reprogramming, and persistent inflammationeBioMedicineJanuary 1, 2026Dandan Yu, Wei-Bo Kang, Yu-Hua Ma, Long-Bao Lv, Shihua Zhang, Lei Tang, Sheng Liu, Jin Zhong, Yong-Gang Yao(AAV8.TBG.mCherry.WPRE.SV40pA and AAV8.CAG.mCherry.WPRE.SV40pA, PackGene Biotech), or universal type I IFN (11200-2, PBL Assay Science). Five animals received 1 × 109 PFU of VSV-GFP and were euthanised at 3 or 7 days

(4) Alternative polyadenylation upon CPSF6 knock-out enhances HIV-1 infection in primary T cellsPLoS PathogDecember 12, 2025Daphne Cornish, Kathryn A. Jackson-Jones, Ted Ling-Hu, Lacy M. Simons, William J. Cisneros, Edmund Osei Kuffour, Natalie Stegman, Francesca Agnes, Yujin Lee, Ved P. Sharma, et al.infection were treated with 100 U/mL (Donors P, Q, and AN) universal type I interferon (PBL Assay Science, #11200–2), IFNα (PBL Assay Science, #11100–1), IFNβ (PeproTech, #300–02BC), or IFNγ (PeproTech, #300–02) or a

(5) Impact of N 6 -methyladenosine (m 6 A) machinery on HIV-1 replication in primary CD4+ T cellsbioRxivNovember 11, 2025Kathryn A. Jackson-Jones, Lacy M. Simons, Siyu Huang, Thea L. Joseph, Aubrey M. Sawyer, Li Wu, Judd F. Hultquist(IFN)-stimulated” cells were stimulated with 1000 U/mL universal type I interferon (IFN) (PBL Assay Science, #11200–2) for 24 hours, post activation with CD3 and CD28 antibodies. RNA extraction and reverse transcription

(6) Convergent evolution in nucleocapsid facilitated SARS-CoV-2 adaptation for human infectionJournal of VirologyJuly 22, 2025Kumari G. Lokugamage, Yiyang Zhou, R. Elias Alvarado, Jessica A. Plante, Yani Ahearn, Jennifer Chen, Leah Estes, William Meyers, Jakob Nilsson, Andrew L. Routh, et al.pretreatment experiments, Vero E6 cells were treated with 1,000 U of recombinant IFNɑ (PBL Assay Science #11200-2) for 18 hours in growth media. Cells were then infected at an MOI of 0.01 as described in the previous

(7) A Type I IFN-Inducing Oncolytic Virus Improves NK Cell-Mediated Killing of Tumor Cells In Vitro Through Multiple MechanismsVirusesJune 25, 2025Elisabeth M. Shiffer, Jeremiah L. Oyer, Alicja J. Copik, Griffith D. Parkscytokine assays, NK cells were treated with 1000 Units/mL of universal interferon type 1 (IFN-1, catalog #11200-2, PBL Assay Science, Piscataway, NJ, USA), unless otherwise noted, and incubated for 18 h. As described

(8) Transcriptional repressor Capicua is a gatekeeper of cell-intrinsic interferon responsesCell Host & MicrobeApril 9, 2025Senthamizharasi Manivasagam, Julianna Han, Athmane Teghanemt, Henry Keen, Boopathi Sownthirarajan, Boyang Cheng, Abhiraj Singh, Abigail Lewis, Olivia A. Vogel, Gayathri Loganathan, et al.AF10015 GM-CSF,Peprotech,Cat# 315-030-100UG IL-4,Peprotech,Cat# 214-14-100UG Universal Type I IFN,PBL assay science,Cat# 11200-2 Protease inhibitor cocktail,Roche,Cat# 11836170001 Tamoxifen,Sigma,Cat# T5648 4-Hydroxytamoxifen,Sigma,Cat#

(9) The CLIC/GEEC pathway regulates particle uptake and formation of the virus-containing compartment (VCC) in HIV-1-infected macrophagesPLoS PathogMarch 11, 2025Kathleen Candor, Lingmei Ding, Sai Balchand, Jason E. Hammonds, Paul Spearmaninternalization were stimulated with 2000 U/ml of universal Type I IFN (PBL Assay Science Cat. No. 11200-2) to upregulate Siglec-1 expression. MDMs for infection experiments were not stimulated with IFN. Reagents,

(10) An essential role for TASL in mouse autoimmune pathogenesis and Toll-like receptor signalingNature communicationsJanuary 24, 2025Lau L, Cariaga TA, Chang AB, Lane JH, Purtha WE, Rapaport AS, Hu R, Konno H, Bulloch DN, Rardin MJ, et al.sensitivity IFN-α ELISA kit (PBL;42115). Plasmacytoid dendritic cells were stimulated with 500U/ml (PBL; 11200-2) Western blots and antibodies Cells were lysed in 1x RIPA buffer (SIGMA; 20-188) supplemented with

(11) Bystander monocytic cells drive infection-independent NLRP3 inflammasome response to SARS-CoV-2mBioOctober 16, 2024Hsieh LL, Looney M, Figueroa A, Massaccesi G, Stavrakis G, Anaya EU, D'Alessio FR, Ordonez AA, Pekosz AS, DeFilippis VR, et al.both IL-18 and IL-1β, or recombinant universal type 1 interferon (1,000 U/mL, PBL Assay Science, cat# 11200-2) all diluted in basolateral media for 4 h at 37°C. The cells were then infected from the apical side

(12) SARS-CoV-2-related bat viruses evade human intrinsic immunity but lack efficient transmission capacityNature microbiologyAugust 1, 2024Peña-Hernández MA, Alfajaro MM, Filler RB, Moriyama M, Keeler EL, Ranglin ZE, Kong Y, Mao T, Menasche BL, Mankowski MC, et al.measured 48 hours after infection. IFN pre-treatments in cell culture and mice. Universal IFNα (#11200–2), human IFNγ (#11500–2) and human IFNλ-IL29 (#11725–1) were purchased from PBL Biosciences. Vero-ACE2/TMPRSS2

(13) The lipopeptide Pam3CSK4 inhibits Rift Valley fever virus infection and protects from encephalitisPLOS PathogensJune 27, 2024Trevor Griesman, Cynthia M. McMillen, Seble Getenet Negatu, Jesse J. Hulahan, Kanupriya Whig, Lenka Dohnalová, Mark Dittmar, Christoph A. Thaiss, Kellie A. Jurado, David C. Schultz, et al.1% P/S and 1% GlutaMAX. Drugs and treatments Universal IFNα was purchased from Fisher scientific (112002), while rat IFNα and rat IFNβ were purchased from PBL Assay Science (13100–1, 13400–1) and rat IFNγ

(14) Development of rhesus macaque astrocyte cell lines supporting infection with a panel of virusesPLOS ONEMay 14, 2024Stefanie Reiter, Ting Sun, Sabine Gärtner, Stefan Pöhlmann, Michael Winklerreported to induce high levels of IFN [23]. For IFN treatment, universal type I IFN-α (pan-Interferon; 11200–2, PBL Assay Science, Piscataway), a chimeric interferon constructed from human IFN alpha A and alpha

(15) Zika virus infection triggers caspase cleavage of STAT1Microbiology spectrumJanuary 11, 2024Shu J, Ma X, Zou J, Yuan Z, Yi Z.(M7449; Sigma) was used at a final concentration of 10 µM. IFN-α was purchased from PBL Assay Science (11200-2). Virus ZIKV MR766 (C7) was generated by electroporation of in vitro-transcribed viral RNAs into Vero cells

(16) A novel highly selective allosteric inhibitor of tyrosine kinase 2 (TYK2) can block inflammation- and autoimmune-related pathwaysCell communication and signaling : CCSOctober 16, 2023Chen CX, Zhang W, Qu S, Xia F, Zhu Y, Chen B.HEK-Blue™ IFN-α/β cells (Invivogen; NKB-IFNAB) were stimulated with human IFNα (200 U/mL; catalog number: 11200–2; PBL Assay Science; Piscataway, NJ, USA) for 6 h. Stimulation of HEK-Blue IFN-α/β cells with human IFNα

(17) SARS-CoV-2 Uses Nonstructural Protein 16 To Evade Restriction by IFIT1 and IFIT3Journal of VirologyFebruary 28, 2023Craig Schindewolf, Kumari Lokugamage, Michelle N. Vu, Bryan A. Johnson, Dionna Scharton, Jessica A. Plante, Birte Kalveram, Patricia A. Crocquet-Valdes, Stephanea Sotcheff, Elizabeth Jaworski, et al.cells were treated for 16 to 20 h prior to infection with Universal Type I IFN (PBL Assay Science No. 11200-2), diluted in Dulbecco’s phosphate-buffered saline, without calcium chloride and magnesium (DPBS, Gibco

(18) Development of immortalized rhesus macaque kidney cells supporting infection with a panel of virusesPloS oneJanuary 1, 2023Reiter S, Gärtner S, Decker K, Pöhlmann S, Winkler M.cells were incubated for 24 h with medium containing 100 U/mL universal type I IFN-α (pan-Interferon; 11200–2, PBL Assay Science, Piscataway), a chimeric interferon constructed from human IFN alpha A and alpha

(19) ISG15 Is a Novel Regulator of Lipid Metabolism during Vaccinia Virus InfectionMicrobiology SpectrumDecember 21, 2022Manuel Albert, Jesús Vázquez, Juan M. Falcón-Pérez, María A. Balboa, Marc Liesa, Jesús Balsinde, Susana Guerravolume of 1× DMEM containing 10% FBS and 500 U/mL of universal type I interferon (PBL Assay Science, 11200-2) at 37°C and 5% CO2 in a humidified incubator. Immunoblotting. Cells were homogenized in lysis buffer

(20) SARS-CoV-2 Uses Nonstructural Protein 16 to Evade Restriction by IFIT1 and IFIT3bioRxivSeptember 29, 2022Craig Schindewolf, Kumari Lokugamage, Michelle N. Vu, Bryan A. Johnson, Dionna Scharton, Jessica A. Plante, Birte Kalveram, Patricia A. Crocquet-Valdes, Stephanea Sotcheff, Elizabeth Jaworski, et al.pre-treatment, cells were treated 16 – 20 hours prior to infection with Universal Type I IFN (PBL Assay Science #11200–2), diluted in Dulbecco’s phosphate-buffered saline, without calcium chloride and magnesium (DPBS, Gibco

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Universal Type I Interferon from PBL Assay Science

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Universal Type I Interferon from PBL Assay Science

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