Human Interferon Beta 1b, E.coli 11420-1 from PBL Assay Science

Product Specs
ItemHuman Interferon Beta 1b, E.coli
CompanyPBL Assay Science
Price $230.00Supplier Page View Company Product Page
Catalog Number11420-1
Purity>95%
SpeciesHuman
Source/Expression SystemE.coli
Molecule NameIFN-Beta
ActivityActivity: 2.0 x 10⁷ u/mg
Format153 mMNaCl + 1.3%
Size1 x 105 Units
Gene NameNotch
TypeProtein
Molecular Weight20,027 Da
NCBI Full Gene Nameinterferon beta 1
NCBI Gene AliasesIFB, IFF, IFN-beta, IFNB

Additional Product Information

Protein/Peptide:
IFN Beta 1b

Protein/Peptide Species:
Human

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PBL Assay Science

131 Ethel Road West. Suite 6

Piscataway, New Jersey

United States

Phone: 1-877-725-8881
1-732-777-9123
1-732-777-9141

Company Profile

Website: www.pblassaysci.com

(1) Increased prevalence of autoantibodies neutralizing IFNλ2/3 in young individuals with cystic fibrosisJournal of Human ImmunityMarch 2, 2026Kevin Groen, Chau Tran, Roger Kuratli, Marie E. Egan, Johannes Trück, Emanuela M. Bruscia, Marc Emmenegger, Benjamin G. HaleIFNλ2 (8417-IL; R&D Systems), IFNλ3 (5259-IL; R&D Systems), IFNα2 (NBP2-34971, Novusbio), and IFNβ (11420-1; PBL Assay Science). IgG subclasses were determined using subclass-specific secondary antibodies. Detection

(2) Cellular targets and lysine selectivity of the HERC5 ISG15 ligaseiScienceFebruary 16, 2024Zhao X, Perez JM, Faull PA, Chan C, Munting FW, Canadeo LA, Cenik C, Huibregtse JM.1073190 Lipofectamine™ RNAiMAX Reagent,Invitrogen,CAT# 13778-150 Human Interferon-β-1b,PBL Assay Science,CAT# 11420-1 Polyethylenimine (PEI),Polysciences,CAT# 24765 Glutathione,Thermo Scientific,CAT# 120000050 Urea,Fisher,CAT#

(3) Restriction factor screening identifies RABGAP1L-mediated disruption of endocytosis as a host antiviral defenseCell reportsMarch 22, 2022Fernbach S, Spieler EE, Busnadiego I, Karakus U, Lkharrazi A, Stertz S, Hale BG.Human IFN-alpha 2 Protein,Novusbio,Cat#NBP2-34971 Recombinant Human IFN Beta 1b,Pbl assay science,Cat#11420-1 Recombinant Human IFN-gamma Protein,Novusbio,Cat#NBP2-34992 Recombinant Human IL-29/IFN-lambda 1 Protein,Novusbio,Cat#NBP2-34996 Dimethyl sulfoxide (DMSO

(4) ISG15 deficiency restricts HIV-1 infectionPLoS pathogensMarch 1, 2022Jurczyszak D, Manganaro L, Buta S, Gruber C, Martin-Fernandez M, Taft J, Patel RS, Cipolla M, Alshammary H, Mulder LCF, et al.above for 3 days and then either stimulated or not with 1000 U/mL of IFNβ1b (PBL Assay Science, cat. 11420–1) for 24h. Cells were lysed in TRIzol Reagent (Invitrogen) and RNA was extracted per the manufacturer’s

(5) TRIM69 Inhibits Vesicular Stomatitis Indiana VirusJournal of virologyOctober 15, 2019Rihn SJ, Aziz MA, Stewart DG, Hughes J, Turnbull ML, Varela M, Sugrue E, Herd CS, Stanifer M, Sinkins SP, et al.S1378-SEL; Stratech), 50 nM bortezomib (2204; Cell Signaling Technology), or 1,000 units of IFN-β (11420-1; PBL Assay Science) immediately before infection (or in the case of IFN-β, 24 h before infection, except

(6) A molecular switch from STAT2-IRF9 to ISGF3 underlies interferon-induced gene transcriptionNature communicationsJuly 2, 2019Platanitis E, Demiroz D, Schneller A, Fischer K, Capelle C, Hartl M, Gossenreiter T, Müller M, Novatchkova M, Decker T.with 250 U/ml of IFN-β (PBL Assay Science; Catalog # 12400-1 (murine) or PBL Assay Science; Catalog # 11420-1 (human)) or with 10 ng/ml IFN-γ (eBioscience; Catalog # 14-8311-63). Seven milliliters of Qiazol Lysis

(7) A repetitive acidic region contributes to the extremely rapid degradation of the cell-context essential protein TRIM52Scientific reportsMay 27, 2019Hacker K, Benke S, Agerer B, Scinicariello S, Budroni V, Versteeg GA.thapsigargin (Sigma, T9033); 10 ng/ml human IL-1β (R&D systems, 201-LB-025); 50 IU/ml human IFNβ (PBL, 11420-1); 10 ng/ml IFNγ (PBL, -11500-2). Western blot analysis and densitometry analysis Cells were lysed

(8) IRF1 Maintains Optimal Constitutive Expression of Antiviral Genes and Regulates the Early Antiviral ResponseFrontiers in immunologyJanuary 1, 2019Panda D, Gjinaj E, Bachu M, Squire E, Novatt H, Ozato K, Rabin RL.stock was determined by plaque assay. Human IFNβ1b was purchased from PBL assay science (catalog # 11420-1). Human IFNλ1 (1598-IL) was purchased from R&D Systems (Minneapolis, MN). Ruxolitinib (catalog # S1378),

(9) Global functional profiling of human ubiquitome identifies E3 ubiquitin ligase DCST1 as a novel negative regulator of Type-I interferon signalingScientific reportsOctober 26, 2016Nair S, Bist P, Dikshit N, Krishnan MN.

(10) IFNB1/interferon-β-induced autophagy in MCF-7 breast cancer cells counteracts its proapoptotic functionAutophagyMarch 7, 2013Malene Ambjørn, Patrick Ejlerskov, Yawei Liu, Michael Lees, Marja Jäättelä, Shohreh Issazadeh-Navikasdone by adding 10 x solutions of control medium (0.1% BSA in PBS), human IFNB1 (PBL InterferonSource, 11420-1), mouse IFNB1 (Sigma, I-9032), rapamycin (Sigma, R0395) or carbobenzoxy-valyl-alanyl-aspartyl-[O-methyl]-fluoromethylketone

(11) Simian immunodeficiency virus SIVagm from African green monkeys does not antagonize endogenous levels of African green monkey tetherin/BST-2Journal of virologyNovember 1, 2009Efrem S Lim, Michael Emerman

(12) The Interferon Response Inhibits HIV Particle Production by Induction of TRIM22PLoS PathogensFebruary 29, 2008Stephen D. Barr, James R. Smiley, Frederic D. BushmanHOS-CD4/CXCR4 cells in log-phase growth 24 hours after human interferon beta (PBL Biomedical Laboratories Cat. #11420-1) treatment using a Qiagen RNeasy Kit. Labeling of RNA was done using standard techniques as described

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Human Interferon Beta 1b, E.coli from PBL Assay Science

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Human Interferon Beta 1b, E.coli from PBL Assay Science

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