Description
Description: IGFBP1 native Human is a single, glycosylated, polypeptide chain containing 218 amino acids and having a molecular mass of 25.3kDa. IGFBP1 is purified by proprietary chromatographic techniques.
Introduction: IGFBP1 is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized