Description
MyBioSource is the leading supplier of human serum Alpha-1-Antitrypsin (A1AT) for medical research and diagnostic manufacturing.
Custom preparations, technical support, bulk quantities and aliquoting available.
Human alpha 1 Antitrypsin or Human A1-antitrypsin (A1AT), also known as serum trypsin inhibitor, protects tissue from enzymes from inflammatory cells, especially elastase and is present in human blood. Disorders of the enzyme include human alpha-1 antitrypsin deficiency, a hereditary disorder in which lack of Human alpha-1 Antitrypsin AAT (A1AT) leads to uninhibited tissue breakdown during inflammation.
Studies indicate that this causes pulmonary emphysema and leads to liver cirrhosis in severe cases. Human alpha-1 antitrypsin protects the lungs from the harmful effects of human neutrophil elastase