Description
Custom preparations, technical support, bulk quantities and aliquoting available.
Human Brain Natriuretic Peptide BNP-32 also known as B-type natriuretic peptide or GC-B has a Peptide Sequence: H-Ser-Pro-Lys-Met-Val-Gin-Gly-Ser-Gly-Cys-Phe-Gly-Arg-Lys-Met-Asp-Arg-lle-Ser-Ser-Ser-Ser-Gly-Leu-Gly-Cys-Lys-Val-Leu-Arg-Arg-His-OH (disulfide bond).
Brain Natriuretic Peptide (BNP-32) is a 32-amino-acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of myocytes (heart muscles cells) in the ventricles. At the time of release, a co-secreted 76 amino acid n-terminal fragment (NT-proBNP) is also released with B-type natriuretic peptide. B-type natriuretic peptide BNP binds to and activates NPRA in a similar fashion to atrial natriuretic peptide but with 10-fold lower affinity. The biological half-life of BNP however, is twice as long as that of ANP. Both ANP and BNP have limited ability to bind and activate NPRB