Recombinant Bovine TNF-alpha Protein 2279-BT-025 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Bovine TNF-alpha Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $388.00Supplier Page View Company Product Page
Catalog Number2279-BT-025
SpeciesBovine
Source/Expression SystemE. coli-derived Recombinant Bovine TNF-alpha Protein
Size25 ug
NCBI Gene AliasesTNF-alpha, TNF-a, TNFa
ApplicationsBioactivity
Conjugate/TagUnconjugated
NCBI Full Gene Nametumor necrosis factor
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution
Molecular Weight17.6 kDa
Purity>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
FormatLyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein
Molecule NameTNF-alpha

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Senescent response in inner annulus fibrosus cells in response to TNFα, H2O2, and TNFα-induced nucleus pulposus senescent secretomePloS oneJanuary 1, 2024Montgomery-Song A, Ashraf S, Santerre P, Kandel R.

(2) Adseverin, an actin-binding protein, modulates hypertrophic chondrocyte differentiation and osteoarthritis progressionScience advancesAugust 4, 2023Chan B, Glogauer M, Wang Y, Wrana J, Chan K, Beier F, Bali S, Hinz B, Parreno J, Ashraf S, et al.

(3) Conserved regulatory logic at accessible and inaccessible chromatin during the acute inflammatory response in mammalsNature communicationsJanuary 25, 2021Alizada A, Khyzha N, Wang L, Antounians L, Chen X, Khor M, Liang M, Rathnakumar K, Weirauch MT, Medina-Rivera A, et al.RP2031-20), and BAECs (#1165 and #1190) were treated with 10-ng/mL recombinant bovine TNFα (R&D Systems, cat# 2279-BT-025) for 45 min in basal Endothelial Cell Growth Media MV2 (PromoCell) without supplements. The unstimulated

(4) Chondroprotective effects of 4-methylumbelliferone and hyaluronan synthase-2 overexpression involve changes in chondrocyte energy metabolismThe Journal of biological chemistryNovember 22, 2019Terabe K, Ohashi Y, Tsuchiya S, Ishizuka S, Knudson CB, Knudson W.

(5) The Mechanism of Diabetic Retinopathy Pathogenesis Unifying Key Lipid Regulators, Sirtuin 1 and Liver X ReceptorEBioMedicineAugust 1, 2017Hammer SS, Beli E, Kady N, Wang Q, Wood K, Lydic TA, Malek G, Saban DR, Wang XX, Hazra S, et al.

(6) High-Throughput Screening of Vascular Endothelium-Destructive or Protective Microenvironments: Cooperative Actions of Extracellular Matrix Composition, Stiffness, and StructureAdvanced healthcare materialsJune 1, 2017Ding Y, Floren M, Tan W.

(7) Isolation of luteal endothelial cells and functional interactions with T lymphocytesReproductionMay 1, 2017S S Walusimbi, L M Wetzel, D H Townson, J L Pateionomycin calcium salt (Sigma); EGM-2 (EBM-2 plus SingleQuot kit of growth factors; Lonza); rbTNF (2279-BT-025; R&D Systems) and rbIL1B (RBOIL1BI; Pierce). Antibodies used for the isolation of T lymphocytes and

(8) G protein-coupled receptor 34 in ovarian granulosa cells of cattle: changes during follicular development and potential functional implicationsDomestic animal endocrinologyApril 1, 2017Spicer LJ, Schütz LF, Williams JA, Schreiber NB, Evans JR, Totty ML, Gilliam JN.

(9) Possible Roles of CC- and CXC-Chemokines in Regulating Bovine Endometrial Function during Early PregnancyInternational journal of molecular sciencesMarch 31, 2017Sakumoto R, Hayashi KG, Fujii S, Kanahara H, Hosoe M, Furusawa T, Kizaki K.

(10) DAMPs Synergize with Cytokines or Fibronectin Fragment on Inducing Chondrolysis but Lose Effect When Acting AloneMediators of inflammationJanuary 1, 2017Ding L, Buckwalter JA, Martin JA.

(11) Interferon regulatory factor 3 is a key regulation factor for inducing the expression of SAMHD1 in antiviral innate immunityScientific reportsJuly 14, 2016Yang S, Zhan Y, Zhou Y, Jiang Y, Zheng X, Yu L, Tong W, Gao F, Li L, Huang Q, et al.

(12) Effect of mesenchymal precursor cells on the systemic inflammatory response and endothelial dysfunction in an ovine model of collagen-induced arthritisPloS oneJanuary 1, 2015Dooley LM, Abdalmula A, Washington EA, Kaufman C, Tudor EM, Ghosh P, Itescu S, Kimpton WG, Bailey SR.

(13) Expression of S100A6 in cardiac myocytes limits apoptosis induced by tumor necrosis factor-alphaThe Journal of biological chemistryOctober 31, 2008Tsoporis JN, Izhar S, Parker TG.

(14) Enhanced 15-HPETE production during oxidant stress induces apoptosis of endothelial cellsProstaglandins & other lipid mediatorsMay 1, 2005Sordillo LM, Weaver JA, Cao YZ, Corl C, Sylte MJ, Mullarky IK.

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Recombinant Bovine TNF-alpha Protein from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Bovine TNF-alpha Protein from R&D Systems, a Bio-Techne Brand

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