Description
Purified Complement C1 protein isolated from human plasma
C1 is the first complement component in the cascade referred to as the classical pathway of complement. C1 binds to and is activated by antibodies bound to antigens (immune complexes) yielding a protease that initiates the cascade. C1 is actually a non-covalent complex of three different proteins (C1q, C1r and C1s) bound together in a calcium-dependent complex