Recombinant Human Alpha-synuclein protein (Tag Free) ab51189 from Abcam

Product Specs
ItemRecombinant Human Alpha-synuclein protein (Tag Free)
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab51189
ApplicationsSDS-PAGE, WB
Size1 mg, 100 µg
Format> 95% by SDS-PAGE
Concentration1 mg/ml
NCBI Gene AliasesNACP, PARK1, PARK4, PD1
Gene NameSNCA
Source/Expression SystemEscherichia coli
ActivityInactive
SpeciesHuman
Research AreaNeuroscience
NCBI Full Gene Namesynuclein alpha
TypeProteins
Molecule NameSNCA

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Malvidin-3-O-Glucoside Mitigates α-Syn and MPTP Co-Induced Oxidative Stress and Apoptosis in Human Microglial HMC3 CellsInternational Journal of Molecular SciencesNovember 27, 2024Rachit Sood, Sanjay, Sung-Ung Kang, Na Young Yoon, Hae-Jeung LeeECH-associated protein 1 (Keap1, ab227828) antibody and recombinant human alpha-synuclein protein (ab51189) were provided by Abcam (Cambridge, UK). M3G (CFN92049) was provided by ChemFaces (Wuhan, China). MPTP hydrochloride

(2) Mechanistic Insight into Intestinal α-Synuclein Aggregation in Parkinson’s Disease Using a Laser-Printed Electrochemical SensorACS Chemical NeuroscienceJuly 17, 2024Julia M. Balsamo, Keren Zhou, Vinay Kammarchedu, Aida Ebrahimi, Elizabeth N. Bessacid (Sigma), 500 μM caffeic acid (TCI America), and 20 μM recombinant human α-syn monomer (Abcam, ab51189) were prepared. Materials were equilibrated to anaerobic conditions before use. Samples were allowed

(3) Mutations in α-synuclein, TDP-43 and tau prolong protein half-life through diminished degradation by lysosomal proteasesMolecular neurodegenerationMay 2, 2023Sampognaro PJ, Arya S, Knudsen GM, Gunderson EL, Sandoval-Perez A, Hodul M, Bowles K, Craik CS, Jacobson MP, Kao AW.cleavage assays For in vitro cleavage assays, 1 µg of recombinant full-length human α-syn (Abcam #ab51189), TDP-43 (R&D #AP-190) or 4N2R tau (rPeptide #T-1001–1) was incubated with or without 1 µM of each protease.

(4) Development of a 36-Channel Instrument for Assaying Biomarkers of Ultralow Concentrations Utilizing Immunomagnetic ReductionACS Measurement Science AuOctober 19, 2022Hsin-Hsien Chen, Ming-Hung Hsu, Kun-Hung Lee, Shieh-Yueh Yang(Aβ1–40: A1075, Sigma; Aβ1–42: A9810, Sigma; T-Tau: T7951, Sigma; p-Tau181: AG-PT1-LTK0, MagQu; α-Syn: ab51189, Abcam; p-α-Syn129: ab188826, Abcam; NfL: ab224840, Abcam; TDP-43: AP-190, R&D) into PBS solution. By

(5) Plasma and Serum Alpha-Synuclein as a Biomarker of Diagnosis in Patients With Parkinson's DiseaseFrontiers in neurologyJanuary 1, 2019Chang CW, Yang SY, Yang CC, Chang CW, Wu YR.the immunocomplex and to establish a standard curve using liquid form of recombinant human α-synuclein protein (ab51189, Abcam, UK) spiked in phosphate buffered saline between αsynuclein level with and reduction in the alternative-current MATERIALS

(6) Novel animal model defines genetic contributions for neuron-to-neuron transfer of α-synucleinScientific ReportsDecember 1, 2017Trevor Tyson, Megan Senchuk, Jason F. Cooper, Sonia George, Jeremy M. Van Raamsdonk, Patrik Brundinβ-mercaptoethanol). Standards were a serial dilution of recombinant human alpha-synuclein protein (ab51189, Abcam). Samples were heated at 95 °C for 5 min then electrophoresed on 4–20% Tris–tricine SDS–polyacrylamide

(7) Autoimmune antibody decline in Parkinson’s disease and Multiple System Atrophy; a step towards immunotherapeutic strategiesMolecular NeurodegenerationJune 7, 2017Tomasz Brudek, Kristian Winge, Jonas Folke, Søren Christensen, Karina Fog, Bente Pakkenberg, Lars Østergaard PedersenFC Microplate Reader,MA,USA. In vitro phosphorylation of human α-synuclein Alpha-synuclein (Abcam #ab51189) was phosphorylated using PLK 2 (Invitrogen Cat# PV4204) at a concentration of 1.44 mg/ml (100 μM).

(8) Development of an ultra-high sensitive immunoassay with plasma biomarker for differentiating Parkinson disease dementia from Parkinson disease using antibody functionalized magnetic nanoparticlesJournal of nanobiotechnologyJune 8, 2016Yang SY, Chiu MJ, Lin CH, Horng HE, Yang CC, Chieh JJ, Chen HH, Liu BH.establish the relationship between the IMR signal and the concentration of α-synuclein, α-synuclein (ab51189, Abcam) spiked in PBS solutions is prepared. For each measurement of the IMR signal, 80-μl reagent is

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Recombinant Human Alpha-synuclein protein (Tag Free) from Abcam

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Recombinant Human Alpha-synuclein protein (Tag Free) from Abcam

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